435032 research outputs found
Sort by
Correction to ‘Impact of surgery and complications on GI recovery after SBO: Insights from the SnapSBO cohort’
No full textLee MJ, Kaplan LJ, Mohseni S, Cimino M, Kurihara H, Martinez-Casas I, et al. Impact of surgery and complications on GI recovery after SBO: Insights from the SnapSBO cohort. Colorectal Dis. 2026; 28:e70411. https://doi.org/10.1111/codi.70411In the above article, Figure 2 was published incorrectly.[Figure presented]The originally published figure did not accurately reflect the impact of surgical complications on nausea, well-being and overall function, and showed an incorrect direction of effect of surgical intervention on nausea.The correct version of Figure 2 is provided below.[Figure presented]We apologize for this error.<p/
How school phone policies influence adolescent phone use and wellbeing (SMART Schools):a qualitative comparative case study
Full text linkRestrictive school phone policies are expected to positively influence adolescent in-school phone use and improve pupil wellbeing. However, there is a lack of research that explains how school phone policies impact on phone use and wellbeing. This qualitative comparative case study aimed to provide such explanatory data. Data were collected from 40 focus group interviews in 7 case study secondary schools in England (4 with permissive phone policies; 3 with restrictive phone policies), with 177 pupil, parent and school staff participants. Data were analysed using thematic analysis. Data show that both restrictive and permissive phone polices have positive and negative impacts on pupil wellbeing. School policies influenced aspects of wellbeing related to health, connectedness, learning, agency and resilience, and the development of safe and supportive environments. Impacts of policies on wellbeing were further shaped by contextual factors. This study presents a conceptual model to inform future research, policy, and practice concerning the ways in which phones—and school phone policies—may shape adolescent wellbeing. The findings underscore that interventions targeting phone use should be integrated within broader, holistic approaches to supporting adolescent wellbeing that operate across both school and out-of-school environments.<br/
Distribution characteristics and ecotoxicological risks of typical organic flame retardants and plasticisers in the Amazon River basin around Manaus, Brazil
Full text linkCurrent understanding of potential anthropogenic/environmental drivers and ecotoxicological risks of emerging contaminants in the Amazon Basin, particularly organic flame retardants and plasticisers, is limited. We collected sediment samples from Amazonian Rivers near Manaus city/Amazonas State, Brazil, and measured concentrations of 39 organic flame retardants and plasticisers, namely: polybrominated diphenyl ethers (PBDEs), novel brominated flame retardants (NBFRs), dechlorane plus (DP), hexabromocyclododecane (HBCDD), organophosphate esters (OPEs), and polychlorinated biphenyls (PCBs). Concentrations of Σ9PBDEs, Σ9NBFRs, Σ2DPs, Σ3HBCDDs, Σ7OPEs, and Σ9PCBs ranged between <0.26 and 5.1, 2.0 – 18, <0.075 – 290, <0.0014 – 0.29, 2.2 – 15, and 0.18 – 3.0 ng/g dw in sediments, respectively. Distribution of legacy BFRs (PBDEs and HBCDD), DPs, and OPEs in sediments was primarily driven by domestic sources; distribution of NBFRs was mainly driven by industrial sources; while distribution of PCBs was primarily modulated by organic matter. We also measured PBDEs in paired surface water samples collected from the Amazon basin near Manaus, with concentrations of Σ9PBDEs ranging between 0.18 and 3.4 ng/L. In contrast to sediments, PBDE concentrations in water were primarily controlled by short-term aggregation and sedimentation enhanced by organic matter. Comparisons of our observations with PNEC (predicted no-effect concentration) values imply high ecotoxicological risks presented by DP, bis(2-ethyl hexyl) tetrabromophthalate (BEH-TEBP), PCB-11, and tris(1-chloro-2-propyl) phosphate (TCIPP) in sediments, and low to medium risks by other pollutants. This is especially striking for DP for which the maximum RQ (Risk Quotient) value was 24.7 at sampling point 1, possibly due to the impact of domestic waste disposal and intensive boat traffic
A Modified Methyl Transferase Cofactor to Selectively Silence Gene Expression in <i>Escherichia coli</i>
Full text linkArtificial control of gene expression in bacteria offers interesting prospects for influencing bacterial pathogenicity and antibiotic resistance. We show that the methyl‐transferase cofactor, AdoHcy azide, can silence gene expression in modified plasmids in some strains of Escherichia coli, where ampicillin and kanamycin resistance as well as eGFP genes were selectively and independently disabled. The disabling of transcription is likely due to steric inhibition during transcription initiation, which is supported by Sanger and nanopore sequencing results. Both sequencing methods showed that 3–6 nucleotides were absent from around the modification site. Postgrowth, extracted AmpR/eGFP plasmid shows evidence of restriction, with sections of the plasmid, including the modification site, missing for the AdoHcy azide modified plasmids. Notably, the AdoHcy azide modification on the DNA appears to be resistant against demethylation in the BL21 strain of E. coli
Family members' experiences of end-of-life care in the home:a systematic review and qualitative content analysis
Full text linkBackground: In recent years, healthcare policy and reform in England has advocated for community care services that enable people to live well and die well at home.Aim: This article is a systematic review that sought to determine the characteristics of a positive experience of home-based, end-of-life care, as perceived by family members.Methods: A combined strategy of electronic and hand searching yielded 11 qualitative studies of European, Australasian and North American origin. The findings were analysed using directed content analysis. Four of the six national Ambitions for Palliative and End-of-Life Care in England were used as the coding framework.Findings: Nine categories were developed from the data to provide a concise, synthesised summary of existing research. Continuity of care, needs-based care and caring and capable staff were dominant category findings. In contrast, accounts of care and support after death were sparse.Implications for practice: Investment in the community nursing workforce and services is essential for the delivery of high quality end-of-life care. It is important to recognise, involve and resource family carers, ensuring continuity and coordination of care and needs-based support before and after death.Conclusions: Further contemporary and contextual research is required to understand and inform the current and future provision of pre- and post-death patient and family care in the home.</p
Branch Orientation:A Potential Indicator of Stem Rehydration and Water Stress
Full text linkSpring rehydration in snow‐covered temperate forests marks a key ecohydrological transition, influencing forest productivity and water balance. Tree water deficit is a key ecohydrological indicator about above ground water status and response to subsurface water availability. But simple measures of rehydration and water deficit are few and the relationship between stem rehydration and simple indicators like structural movement linked to branch orientation remains poorly understood. We investigated the coordination between stem rehydration, tree water deficit and branch movement in Abies balsamea using high‐resolution dendrometer data and time‐lapse imagery from early March to mid‐May in Ontario, Canada. In this video and data, we showed that upward branch movement consistently aligned with stem radius expansion during snowmelt and after rainfall events, while downward branch posture corresponded with dry periods and increased tree water deficit. Freeze–thaw events caused abrupt stem shrinkage but had limited influence on branch position. These findings suggest that branch posture reflects stem water status, potentially offering a visual and qualitative indicator of subsurface water availability to trees. While this is not a substitute for physiological measurements, branch movement could support field‐based monitoring of rehydration dynamics and further new opportunities to tree water relation studies. As climate change alters snowmelt timing and moisture regimes, integrating structural and physiological indicators may enhance our understanding of plant–water interactions in cold‐region ecosystems
Mapping the Situation of Unaccompanied and Separated Children in Greece:A Scoping Review
No full textBiogeophysical Impact of Land-Use Scenarios on Holocene Surface Temperatures
Full text linkReconstructions and simulations disagree on whether the Holocene exhibited a long-term cooling or warming signal. Anthropogenic land-use could be an important forcing regionally, but available population-based estimates differ widely. We examine transient Holocene climate model simulations forced with three population-based disturbed-land reconstructions and compare this with a fourth scenario derived entirely from fossil pollen records. The direct biophysical temperature effects are broadly similar across the scenarios but the pollen-based product suggests an earlier onset of disturbance, particularly in China and accounting for its limited spatial coverage, falls closer to the upper limit of the existing uncertainty range. Impacts in many areas begin during the mid-Holocene but emergence of a signal varies spatially with earliest impacts over Europe, China and the North Atlantic. Significant uncertainties remain, and these could be tackled by improving the representation of land-use effects in climate models or by merging different information sources related to Holocene land-use
Quality over Quantity:Organic Compounds Altering the Antarctic Sea Spray Aerosol Concentrations
Full text linkThe Antarctic coastal zones are among the most biologically productive areas on Earth. The effect of marine microbiota on the emissions of sea spray particles, a critical factor for global climate and clouds, remains an open and actively researched question. Here, by means of in situ ship-borne bubble-bursting SSA production experiments at multiple locations around the Antarctic Peninsula, we show a 2-fold variability in the 10–500 nm size-resolved SSA number concentrations. We observed that the organic chemical composition of seawater (SW) and surface microlayers (SML) clearly impacts SSA number concentrations. SW and SML samples with saccharides, proteins, and N-osmolytes were less efficient at emitting SSA compared with waters rich in biotic material originating from lipids, such as fatty acids and polyols. We found that the dissolved organic carbon (DOC) fraction containing lipid degradation products and polyols indicates higher SSA production. Our results indicate that low concentration organic components, rather than the most abundant classes of biomolecules, influence the ability to be aerosolized, with strong chemical selectivity affecting SSA production
Green extraction of antioxidants from Brewer's spent grain using Ohmic-accelerated steam distillation with NaCl electrolytes
Full text linkThis study proposed an Ohmic-Accelerated Steam Distillation (OASD) process and systematically evaluated the effects of electric-field strength (0-40 V/cm) and NaCl concentration (0-0.10 M). The key findings demonstrate that the combined electric field and ionic enhancement significantly accelerated mass transfer and markedly improved the recovery of major bioactive compounds. An optimal synergy was found at 15 V/cm with 0.01 M NaCl, which yielded extraction efficiencies of 41% for antioxidants and 30% for phenolics while substantially reducing extraction time from > 5.5h (without electric field and/or NaCl) to 50-60 min. Scanning electron microscopy and confocal laser scanning microscopy revealed increased cell-wall permeability with moderate structural disruption, consistent with enhanced mass transfer. Under these conditions, HPLC quantified recoveries of key bioactives-caffeic acid 48%, ferulic acid 69%, vanillic acid 67%, and tannins 75%. CLSM fluorescence analysis revealed a significant decrease in antioxidant-related regions (from 7899 to 1252 px2), further confirming enhanced extraction efficiency. Compared to conventional thermal extraction approaches, the optimized OASD method significantly improved bioactive recovery while preserving cellular integrity and reducing thermal degradation. This approach offers strong potential for applications in functional foods and health-related products, contributing to by-product valorization and the advancement of the circular economy in the food industry
Data sources:
Access Repository Dashboard
Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇