Res Medica (E-Journal)
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Book Review
Get PDFCLINICAL CHEMISTRY IN PRACTICAL MEDICINE By C. P. Stewart and D. M. Dunlop.Fifth edition, 1958. E. & S. Livingstone Ltd., 27s 6d. To the casual observer, this new edition would seem to differ from its predecessors only in a somewhat more logical order, an additional 22 pages and an increase in price. Closer examination reveals, however, that a far more extensive revision has been undertaken,and that as many sections, notably the gastric and renal tests, have been reduced,the amount of new material included is greater than the additional pages might suggest. Large increases are to be found in those sections devoted to water andelectrolyte balance, to the steroid hormones, and to the metabolic abnormalities, while the accounts of such subjects as electrophoretic fractionation, the histamine stimulation of gastric function and the intravenous glucose tolerance curves are much expanded
The Treatment of Cancer
Get PDFBased on a Dissertation read before the Royal Medical Society on Friday, 16th January 1959.AN overall view of the adequacy of the treatment of cancer at the moment presents a very dismal picture. To be satisfactory this treatment must mean cure, but until the cause or causes of cancer are known this will seldom be achieved. The possible means of treatment available are:-Surgery, Radiotherapy. Chemotherapy, Serotherapy and Psychobiological methods. Prophylactic measures designed to prevent a person from getting cancer are, of course, of great importance also
Debility and/or Loss of Weight the Diagnostic Approach
Get PDFThese last few decades have given us greatly increased precision of diagnosis and therapeutic power, and we, no longer merit Matthew Arnold\u27s rebuke. These revolutionary changes have been produced as a result of a great spirit of free enquiry, a search for facts and their explanation. Such a search is dependent initially on the development of a working hypothesis, and this is just what a tentative diagnosis is. From this point our search is for facts uncoloured by accepted authority, popular opinion or personal prejudice.In medicine Galen of Pergamum was the "Master" for many centuries, and from 200 A.D. the dead hand of Galen\u27s authority lay upon medicine for over 1300 years. The mighty Leonardo da Vinci first questioned Galen\u27s views and in England in 1620 Francis Bacon in his "Novum Organum" urged men to abandon their four idols-accepted authority, popular opinion, legal bias and personal prejudice. Yet, despite Leonardo da Vinci and Bacon and even the revolutionary work of Harvey in 1628, it was not until the time of Lister (186o) that medicine ceased to be a traditional empirical art bound to the words of the Master and accepted authority.There are for us three kinds of facts, viz. symptoms, signs and the results of investigations, and upon these we base our diagnosis. It is because of the difficulty in setting down an accurate account of the first of these that medicine will be for ever an art
Some Aspects of Abdominal Pain
Get PDFBased on a Talk given to the Society on 7th February, 1964.Pain is one of the many facets of our education where we learn the basic facts and theories in the early years of our medical course only to forget much of our learning by the time we are qualified and in practice. In the clinical years we tend too often to learn sites and types of pain by memory, each type associated with one certain disease: all too rarely do we stop and ask ourselves the question “Why? “ and attempt to reconsider the basic theories in the light of the present evidence. It is a healthy attitude to challenge current teaching now and then in order to see how well it matches up to current practice and current evidence
Res Medica, Spring 1965, Volume IV, Number 4
Get PDFTABLE OF CONTENTSTHE HISTORY AND EVOLUTION OF PLASTIC SURGERY: A.B. Wallace, M.Sc, F.R.C.S.Ed.SYSTEMIC LUPUS ERYTHEMATOSUS: R. McD. FoxMUSCLE SPINDLES: A.J. Strong, B.AJ. B. BAIKIE—DOCTOR AND EXPLORER: J.B. King, M.D., F.R.C.P.Ed.RES MEDICA LOOKING TOWARDS POST-GRADUATE EDUCATION FROM OUR LIBRARYREHABILITATION SERVICES FOR THE INJURED: R.R.S. HowardASPECTS OF HOMEOPATHY: I.J. McKe
Res Medica, Winter 1965-66, Volume V, Number 1
Get PDFTABLE OF CONTENTSSELF POISONING - A STUDY IN EDINBURGH: Neil KesselON THE MODE IN WHISLT EXTERNAL APPLICATIONS ACT ON INTERNAL PARTS: Joseph Lister WAYSIDE HOUSES OF ILL-REPUTE —DIVERTICULAR DISEASE OF THE COLON: T. W. BalfourANAESTHESIA IN PATIENTS WITH CARDIAC OR RESPIRATORY DISEASE: J. D. Robertson. M.D., F.R.C.P., F.R.C.S.E., F.F.A.R.C.S., D.A.PRE-ECLAMPTIC TOXAEMIA OF PREGNANCY: R. C. Heading, B.Sc.THE SOCIETYRES MEDICABOOK REVIEW
Headache
Get PDFFrom a dissertation read before the Society on February 4th, 1966.Headache is a symptom which may be a feature of a wide range of conditions, arising not only with pathology in the head but also in cardio-vascular, renal, metabolic, orthopaedic and psychiatric conditions. It is extremely common, and usually transitory. Yet it may be a symptom of great significance in clinical practice. The underlying mechanisms are largely unknown. The explanations of the cause of headaches have a long history, and it is on the aetiology of headache that this discussion will centre.Headache can be a dramatic symptom and presumably has been ever since primitive man drank a fermented juice to excess and had his first hangover, or woke up with his first postconcussional headache to find that his wife had been kidnapped
The Structure and Function of Immunoglobulins in Man
Get PDFThe cells of the blood, and their supporting fluid are among the most extensively studied biological systems. It is with the fluid portion of the blood that this article is concerned and with a small group of proteins in particular, the immunoglobulins. These show a peculiar and unique behaviour in the presence of other substances called antigens. This behaviour may take the form of combination forming an insoluble precipitate (precipitin reaction), or rendering it more easily phagocytosed by the microphages or macrophages (opsonisation). Other reactions between antibody globulin and antigen are complement fixation in which the four components of complement take part, immune adherence between antigen and adsorbed antibody, and sensitivity reactions such as passive cutaneous anaphylaxis and the Prausnitz-Kustner reaction. However, the central feature of immune reactions is that antibody by definition can only be identified by its reaction with antigen. Identifiable antibody forms only a small part of the total globulin fraction of serum. The remaining globulin may be physically indistinguishable from antibody, but lacks its demonstrably specific activity; this has resulted in the term “Immunoglobulin” being substituted for “antibody” in this article whenever this sense is intended. The greatest barrier to the understanding of the nature of immunoglobulins is the classification used to describe them
The Hip – from Cradle to Grave
Get PDFFrom a dissertation read before the Society on Friday, 26th November, 1965From birth to old age the hip joint provides a fascinating spectrum of disease processes; this provides a useful starting point for a study of the interaction of development of structure with development of function and the pathological variants of this interaction. Because of limitations of space only a few disease processes will be chosen and much of the review will be devoted to normal structure and function
Research Topic: A Study Of Fibrinolysis
Get PDFAccording to present concepts, the enzyme responsible for the dissolution of fibrin both intra - and extra - vascularly is generated by the action of an “activator” upon the enzyme precursor plasminogen. Plasminogen is a B-globulin, of molecular weight of the order of 143,000, and a normal constituent of human plasma. It is known to possess a high affinity for both fibrin and fibrinogen, a property fundamental to the Sherry hypothesis of the physiological function of plasminogen where any fibrin clot is visualised as having an intrinsic plasminogen content sufficient to ensure its lysis when activated. The activation is achieved by activator either trapped within the clot at the moment of polymerisation, or diffusing subsequently into the clot from the surrounding liquid phase