Res Medica (E-Journal)
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Some Aspects of Pyelonephritis
In a short article it is only possible to outline the important advances in our knowledge of the serious and often fatal disease—pyelonephritis. This pathological entity has been well recognised since the nineteenth century but interest in its clinical aspects has only been aroused since the end of the second world war. Prior to this little attention was paid to pyelonephritis by clinical workers until the classical paper of Longcope (1937). The disease is very protean in its presentation which makes a clear definition of the term pyelonephritis difficult.Acute or chronic pyelonephritis may arise in normal kidneys by infection with microorganisms or in kidneys structurally altered by prior disease processes or congenital malformations
The Status of Antibiotics
From a dissertation read before the Royal Medical Society on Friday, 1st November, 1963.Many attribute the earliest recognition of an antibiotic effect to Sir Alexander Fleming. However, in 1877, 50 years before Fleming’s discovery, Pasteur and Joubert described the phenomenon of bacterial antagonism; the process whereby the growth of certain species is inhibited in the presence of others. In the particular case of the anthrax bacillus they found that growth was inhibited in cultures contaminated with ‘common bacteria’ (those types now known as the Enterobacteriaciae). Shortly afterwards the term “antibiosis” was introduced for such antagonism
Muscle Spindles
Based on a Dissertation presented to the Society on 6th November, 1964The action of our muscles is controlled with a remarkable delicacy, and components of the nervous system at every level contribute to this. On the afferent side, the stretch receptors of muscle spindles are the most peripheral elements and have been known to histologists and physiologists for more than a century, Hassall must receive the credit for the discovery of muscle spindles in 1851, but the first systematic description was Weissmann’s in 1861. Each spindle consists of a parallel bundle of striated muscle fibres—intrafusal fibres. The bundle is 7 to 12 mm. long, and is surrounded by what Sherrington later called the lymph space, because he was able to inject it with dye via the lymph vessels: this space is enclosed by a thin fibrous capsule. The intrafusal fibres vary in their length and diameter, and are attached to one another at their ends; the ends of the longest fibres are attached to extrafusal endomysium. The spindle is supplied with nerves of various diameters terminating in different types of ending on the intrafusal fibres
On the Mode in which External Applications Act on Internal Parts
From a dissertation by Joseph ListerLister joined the Royal Medical Society in 1854 and delivered this dissertation to the Society on 21st December 1855. In this dissertation he propounds the idea that there is "sympathy" between external and internal parts such that treatment of internal disease can be adequately treated by applications to the skin such as leeching, cautery and blistering. He illustrates conditions which may be treated by external applications, and attempts to describe the physiological basis of the treatment
Res Medica, Spring 1967, Volume V, Number 3
EDITORIALNEUROLOGICAL EXAMINATION: JB Stanton, F.R.C.P.E., F.R.C.P., D.P.M. CIRCULATORY STABILITY: N.C.H. Stott, B.S.c., M.B.Ch.B. CHANGING CONCEPTS OF THE AETIOLOGY OF DIABETES MELLITUSDIAGNOSTIC PROBLEMPOLYCYTHAEMIA: A. W. DELLIPIANI, M.B., M.R.C.P.E. THE CONTRIBUTORSRESEARCH TOPIC: N.BAKERELECTRON MICROSCOPY IN GLOMERULONEPHRITIS: M. K. McDONALD, M.B., Ch.B., F.R.C.P.(Ed.)THE STRUCTURE AND FUNCTION OF IMMUNOGLOBULINS: J. A. HABESHAW, B.Sc., M.B., Ch.B. THE SOCIETYBOOK REVIEW
Some Aspects of Circulatory Stability
Based on a dissertation read before the Society on 11th February, 1966.The secrets of the circulatory system taxed the imaginations and resources of workers in every field of medicine long before even William Harvey produced his classical treatise in 1628 . Now , in 1966, the basic anatomy of the circulatory system is widely accepted but the relative importance of various homeostatic mechanisms in the patho-physiology of this system is still the subject of constant debate; this is no mere ‘academic exercise’, for the disorders of the circulatory system are becoming major problems throughout the world and they merit careful consideration. Nevertheless this dissertation is not a review. I attempt to outline a few aspects of the subject which are of particular interest, and so well accepted and established concepts are included along with some more recent work
Res Medica, Volume 1, Number 1, 1957
TABLE OF CONTENTSEDITORIAL TO BE OR NOT TO BE — A DOCTOR: Sir Stanley Davidson, B.A., M.D., P.R.C.P.E., F.R.C.P.( LOND.), Q.H.P. BENJAMIN FRANKLIN: Forrester Cockburn MODERN CONCEPTS OF BREAST CARCINOMA: Sir Arthur Porritt , K.C.M.G., C.B.E.,M.A., M.ch., F.R.C.S. NORTH AMERICAN KALEIDOSCOPE: Alastair G. MacGregor , B.SC., M.D., F.R.F.P.S.G.,M.R.C.P.E., M.R.C.P. BRONCHOGENIC CARCINOMA: James A. GrayOPERA OCCULTA: Collected from the Society’s archives: C. Vaughan Ruckle
The Royal Medical Society To-day
We have often heard that our University, with its paucity of halls of residence and common rooms used for the right purpose, is fast developing the atmosphere of a huge and impersonal technical college. The undergraduate, his brain dulled by the heavy aroma of haddock, emerges each morning from his “digs”. He returns in the early evening to decipher a sheaf of laboriously scribbled notes that might even be headed by the “good morning, ladies and gentlemen” with which his lecturer aroused him from complete coma into the semi-conscious state in which the rest of his day is spent. He has contributed nothing to, and has gained nothing from his day at the “University.
Full issue Res Medica, Autumn 1958, Volume 1, Number 3
TABLE OF CONTENTSEDITORIALSYLLABUS FOR 222nd SESSIONCANCER RESEARCH: ITS HISTORY AND PROSPECTS: Professor Alexander Haddow, M.D., D.Sc.,F.R.S.THE SOCIETY’S LIBRARY: J. J. C. CormackBIOLOGICAL RESERVES: Sir James Learmonth, K.C.V.O., C.B.E., F.R.S.Ed., F.R.C.S.Ed. and Eng., M.D.THE CAUSATION AND SPREAD OF EPIDEMIC INFLUENZA: William Ian Shedden, B.Sc.(Hons.)SOME ASPECTS OF POLIOMYELITIS: Allan Milne,M.B., Ch.B.BOOK REVIEWOPERA OCCULTA: Henry C. Drysdale
The Diagnosis of Chest Disease
This is not an article on the latest means available for the diagnosis of chest diseases, but simply a consideration of history taking and of signs and symptoms. Medicine is without meaning unless we think in terms of patients. It is by developing our powers of observation and interpretation while we are in contact with our patients that we learn medicine, rather than from books and articles.Hippocrates is our great master of the art of inspection-he stands for the fundamental importance of seeing clearly. To-day if we read his reports of 2,400 years ago we can often make an almost instantaneous diagnosis. Descriptions which cannot be bettered are the squeaking of leather for a pleural friction rub, or the boiling inside the chest of pulmonary oedema. In the time of Hippocrates as much as now thoroughness in examination produces more correct diagnoses than sudden flashes of brilliance