Res Medica (E-Journal)
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    Book Reviews

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    Clinical Examination Edited by John Macleod. E. & S. Livingstone Ltd. 1964. First edition. Pp. 513. Price 35s.Techniques in Chemical Pathology, by G. A. Cheyne. 397 pages. Price 42/-. Published by Blackwell Scientific Publications, Oxford.The Principles and Practice of Medicine Edited by Sir Stanley Davidson. E. & S. Livingstone Ltd. 1964. Seventh Edition. Pp. 1260. Price 37s. 6d.Tropical Disease Supplement to Tile Principles and Practice of Medicine. By Sir Alexander Biggam and Frederick J. Wright. E. & S. Livingstone Ltd. 1964.Lecture Notes on Psychological Medicine By T. Ferguson Rodger and 1. M. Ingram, G. C. Timbury, R. M. Mowbray. E. & S. Livingstone Ltd., 1964. Second edition. Pp. 108. Price 7s. 6d.Janus in the Doorway  by Douglas Guthrie. Pitman Medical Publishing Co. Ltd. Price 50/-.The Biochemical Approach to Life by F. R. Jevons. Pages 182. Price 28/-. Published by George Allen & Unwin Ltd. (London), 1964.A Synopsis of Cardiology  by D. Weitznian. John Wright & Sons Ltd., Bristol. 1964. 30/-.A Short History of Chalmers Hospital by W. N. Boog Watson. E. & S. Livingstone Ltd., 1964. 2/ 6

    Self poisoning – A study in Edinburgh

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    Years ago the problem of self-poisoning was not recognised. People poisoned themselves, of course, but few survived.The picture today is different. In Edinburgh more than a thousand adults are admitted to hospital each year after such an act. The great majority of those who poison themselves survive, and this fact goes far towards explaining why the practice has spread.Poisoning used to be regarded as fatal. Instances of someone taking poisons deliberately to harm himself, but with the intent ion of surviving, are hard to find. Juliet did so, but Romeo had so little thought that she might not be dead that he killed himself in despair. He knew, as everyone knew, that if you took poison you died. This is not so today.The growth of pharmaceutical products has brought about the change. The growth of self poisoning has come about in the train of a rapid rise in number of highly dangerous preparations employed therapeutically, together with a great contemporaneous increase in prescribing. The way has thus been opened for self -poisoning to flourish, since few who practise it have their minds set on dying

    Book Reviews

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    EXPLORATION MEDICINE. O. G. Edholm. A. L. Bacharade, Editors. John Wright & Sons, 46/-. P.410.RADIOLOGY FOR GENERAL PRACTITIONERS AND MEDICAL STUDENTS. David Sutton. E. & S. Livingstone. 12s. 6d.THE ART OF GENERAL PRACTICE David Morell. E. & S. Livingstone

    The Field of Allergy

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    A review based on a dissertation read before the Society on 10th December, 1965.This article concentrates on (i) the immunological basis, (ii) pathophysiological mechanisms, and (iii) control (theoretical and practical) of the immediate-type allergy.Antigen-antibody reactions constitute an important group of defences, facilitating phagocytosis and blocking the toxic effects of parasitic poisons. The reaction confers ‘immunity’. The combination of antigen and antibody is, however, not always beneficial. Pathological reactions as severe or more severe than the affect of the antigen alone arc sometimes noticed. Hypersensitivity or allergic reactions form major examples of such conditions. Allergy or hypersensitivity may be defined as a state in which the animal reacts in an excessive way to the introduction of an antigen or a hapten even though the antigen or hapten may be innocuous. Not all instances of hypersensitivity enjoy the identification of the exciting antigens, the mediating antibodies and the mechanisms of tissue damage

    Res Medica; Abortive Legislation?

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    For the back-street abortionist business is booming. It is commonly estimated that some 100,000 criminal abortions are performed annually in England and Wales alone. Maternal deaths from these are, according to Goodhart (1964) of the order of 35 per year in England and Wales, giving a surprisingly low maternal mortality of 0.35 per 1,000 which equals maternal mortality from all other causes. Serious maternal morbidity, however, defies estimate but must be alarmingly high. Even in hospital, the operation carries serious risk of complication, which is obviously greatly increased in a tenement kitchen. Cervical in competence, causing repeated miscarriage, serious infection, especially pelvic peritonitis, and severe anaemia from haemorrhage are but some of the scars which a woman may carry for many years, as a result of such treatment. The scar of the psychological trauma may well be carried for life

    Sex Chromosome Abnormalities in the Male

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    This article does not set out to give a comprehensive review of sex chromosome abnormalities in Man, nor even in phenotypic males. Its purpose is more to outline a few general principles and show how they apply to one group of individuals with one class of abnormality, namely males with abnormalities of number of either the X chromosome, or the Y chromosome or of both

    Changing Concepts of the Cause of Diabetes Mellitus

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    Probably the first allusion to diabetes is contained in the papyrus Ebers, dated at about 1500 B .C . and the symptomatology of the disorder was described by Aretaeus in the 1st century A.D. Prior to the late 17th century the causation of diabetes was variously ascribed to excessive food, alcohol, sex or grief or to maladies of the stomach, arteries, blood, nervous and other systems. However, in 1683 the Swiss Brunner recorded that pancreatectomised dogs displayed great thirst and polyuria before dying in coma, and in 1788 Cawley reported destruction of the pancreatic tissue in a patient dying of diabetes. These observations were largely disregarded until further evidence of a possible relationship between diabetes and the pancreas was provided by the classical experiments of von Mering and Minkowski in 1890. Twenty years earlier Langerhans, when aged 20, had described the islets to which his name was given in 1893 by Laguesse who was the first to suggest that they might produce an internal secretion. Schafer in 1895 considered that this secretion might profoundly modify the carbohydrate metabolism of the tissues and the name “ insuline” was proposed by de Meyer in 1909

    Diagnostic Problem

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    S u b je c t:C.S., married, female, aged 33. Housewife.Past History:1. Usual childhood illnesses.2. Pneumonia on three occasions between the ages of 3 and 5 years.3. Rheumatic fever, aged 9 years.4. Tonsillectomy, aged 10 years.5. Appendicectomy, aged 16 years.6. The patient had two normal pregnancies, aged 23 and 24 years.7. Perforation of duodenal ulcer, aged 25 years. — Gastroenterostomy.8. Gradually progressive exertional dyspnoea began, aged 27.9. Two miscarriages, aged 28, followed by tubal ligation on the grounds of rheumatic heart disease.10. Mitral valvulotomy successfully carried out, aged 29, with relief of symptoms.11. Recurrence of classical acute rheumatism, aged 30

    The Contributors

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    Professor John Gillingham, head of the Department of Surgical Neurology, Royal infirmary of Edinburgh and Western General Hospital, is a world authority on stereotaxic techniques in Parkinsonism. In conjunction with the Department of Medical Physics he is also introducing automatic patient monitoring for the detailed study of head and spinal injuries. Dr Edward Frenc

    Opera Occulta

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    With a mixture of pride and humility I began to turn the pages of the great leather-backed volumes which enclose the early Dissertations of the Royal Medical Society. It was something to be done with care, for the pages are brittle and cachetic. The regular, flowing, almost copper-plate writing is only s lightly faded and is eminently legible. We, who can achieve immaculate script only through the medium of machinery, might pause and consider the scholarship of our predecessors who wrote Greek, Latin or English with artists’ hands

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