Res Medica (E-Journal)
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RMS Council 266th Session
Senior President: David Cavanagh1st Junior President: Joanne Sells2nd Junior President: Paul Jenkins3rd Junior President: Thomas Rus
Book Review: Davidson’s Principles and Practice of Medicine, 19th edition
The first edition of Davidson’s appeared in 1952; an almost pocket-sized volume which promised to concentrate on common disorders and everyday problems illustrated by an account of the applied anatomy and physiology of the relevant system. The textbook has come a long way since then, but remains true to its original ideals
Palliative Care Experiences in the Pretoria Sungardens Hospice, South Africa
The Pretoria Sungardens Hospice, South Africa was the beautiful location of my summer project. Saunders and Sykes (1993) define a Hospice as “a centre that would specialize in pain and symptom control in the terminal stages of disease but also provide an environment that would allow people to adjust emotionally and spiritually to their approaching death” . The Sungardens Hospice seems to fill these criteria perfectly
Two Diplomas Awarded to George Joseph Bell now in the Possession of the Royal Medical Society
The two earliest diplomas in the possession of the Royal Medical Society were both awarded to George Joseph Bell, BA Oxford. One of these diplomas was his Extraordinary Membership Diploma that was awarded to him on 5 April 1839. Very few of these Diplomas appear to have survived, and the critical introductory part of his Diploma is inscribed as follows:Ingenuus ornatissimusque Vir Georgius Jos. Bell dum socius nobis per tres annos interfuit, plurima eademque pulcherrima, hand minus ingenii f elicis, quam diligentiae insignis, animique ad optimum quodque parati, exempla in medium protulit. In quorum fidem has literas, meritis tantum concessus, manibus nostris sigilloque munitas, discedenti lubentissime donatus.2 Edinburgi 5 Aprilis 1839.
The Scottish Contribution to the Development of Obstetrics
Among the many things in which the Scots nation can take pride our contribution to medical science has been of a very high order. This perhaps reached its acme in the 18th and 19th centuries when Scotland in general and Edinburgh in particular represented the magnet for medical trainees from across the globe. The catalogue of Scottish contributions to developments in medicine is enormous but perhaps in no branch of medicine is it greater than in obstetrics. It could be reasonably claimed that in compiling a list of those obstetricians from the British Isles who have made the most telling contributions to the advancement of this clinical discipline the first half dozen names would probably be Scots. This short article will highlight some of the famous obstetricians who have helped to bring the art and science of obstetrics out of the mists of obscurity to the highly developed clinical science of today
Modern Epidemic
All I have to say comes from prospective studies of ischaemic heart disease made in America and in this country since World War II. In Framingham, as in the other surveys, all those who already had signs of ischaemic heart disease were put aside, and the great majority who showed no evidence of it were followed up over the years. More men than women developed the disease during middle age. In this age group, there are three main manifestations of ischaemic heart disease - sudden death, classical myocardial infarction, and angina pectoris. When the total picture in Framingham was divided up according to these different modes of presentation, they found that in those who develop angina pectoris without classical infarction there is some excess of males in the thirties; near equality in the forties; in their fifties more women were affected than men. Many of these people of course do not come for medical care, they have these symptoms but ignore them
The Investigation of a patient believed to have a blood disorder
One of the difficulties of writing an article on this subject is that of finding a suitable title, since one is not dealing with a system of the body in the usual sense of the term, but, instead, with a number of conditions which arerelated only in that an abnormality exists either in the formed elements or the clotting mechanism of the blood. Accordingly there is a great variation in the spectrum of possible physical abnormalities and, indeed, there may be a serious blood disorder with neither symptoms nor signs.For this reason it is necessary to approach the subject in a manner somewhat different to that employed by other writers in the current series of articles, and to stress particularly the importance of both the history and the laboratory investigations
The Rectal Examination
A quotation attributed to one of England’s leading rectal surgeons, fondly known as the “Rear Admiral”, states: “If you do not put your finger in, you will put your foot in it” ; implying that a routine “ physical” is not complete without a competent rectal examination, and failure to acknowledge this fact may lead you and your patient into serious trouble.Words such as distasteful, repugnant, inaesthetic, are often chosen to describe the “rectal” . Such adjectives in this context stem from a false modesty and the complicated rituals of excretion which afflict a modern urban civilization. The result is that many people consider a per rectum (P.R.) examination to be an affront to the person or at least “not quite nice”. Negative attitudes of this kind cannot be tolerated within the profession who must accept a P.R. as the routine final act of the complete physical examination
Growth Hormone and the Lipolysis of Exercise
From a dissertation read before the Society on January 22nd. 1969.Growth hormone (GH) is secreted by the acidophil cells of the anterior pituitary. It is a protein, partially α-helix in structure, of molecular weight 29,000 in man (1 ). In addition to its effect in promoting growth several metabolic effects follow its administration, one of which, the mobilisation of free fatty acid (FFA) from adipose tissue, will be discussed in some detail.The radio-immunoassay methods for estimating GH (2, 3) which are the most sensitive and accurate now available, depend on the fact that radio-iodinated GH of high specific activity (4) competes with standard or test GH in plasma for binding sites on a γ-globulin in antiserum prepared in rabbits. The competition results in ‘bound’ and ‘free’ 131I-GH which are separable electrophoretically and counted for radio-activity. Inhibition curves relating bound: free ratios to standards are drawn and test samples assayed against them.There is good evidence that the assay is specific (5). Reactive material is elevated in acromegaly and is absent after hypophysectomy: jugular vein plasma contains more than inferior vena cava plasma: cross-reaction occurs between plasma samples only from species whose pituitaries contain cross-reactive material: acromegalic plasma acts just as a plasma dilution of pituitary extract