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species correlates with rain and host structure in a central Mexican tropical dry forest
No full textEffects of element complexes containing Fe, Zn and Mn on artificial morel’s biological characteristics and soil bacterial community structures
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Tamoxifen use and acute pancreatitis: A population-based cohort study
No full textSeveral case reports have indicated that tamoxifen induced acute pancreatitis (AP); but no pharmacoepidemiological data support the claim. Therefore, we investigated whether tamoxifen use is correlated with the risk of AP in patients with breast cancer.This population-based cohort study used the Taiwan National Health Insurance Research Database. A cohort of 22 005 patients aged ≥20 years with breast cancer from January 1, 2000 to December 31, 2009 was identified and the date of cancer diagnosis was set as the index date. The end point was developing AP during the follow-up. Hazard ratios (HRs) and 95% confidence intervals (CIs) were evaluated to determine the correlation between the risk of AP and tamoxifen use. Because the drug use varied over time, it was measured as a time-dependent covariate in the Cox proportional hazard model. The same approaches were applied in PS-matched cohorts.After adjustment for covariates and medication use including fluorouracil and doxorubicin, the risk of AP was not significant between tamoxifen users and tamoxifen nonusers (adjusted HR = 0.94, 95% CI = 0.74–1.19) in the non-matching cohorts. The results revealed no dose–response trend between tamoxifen use and the risk of AP (adjusted HR = 0.98, 95% CI = 0.96–1.00). The comorbidities DM and gallstones were associated with a significantly increased risk of AP. Similar trends were observed in PS-matched cohorts.No significant correlation was observed between tamoxifen use and the risk of AP in patients with breast cancer
Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer’s Mouse Model
No full textA large population-based association study between HLA and KIR genotypes and measles vaccine antibody responses
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Argon does not affect cerebral circulation or metabolism in male humans
No full text), glucose (AJVDG), and lactate (AJVDL) in anesthetized patients., AJVDG and AJVDL were calculated as the differences in contents between arterial and jugular-venous blood of oxygen, glucose, and lactate. Statistical analysis was done by t-tests and ANOVA., AJVDG, and AJVDL.Short-term inhalation of 70% Ar does not affect global cerebral circulation or metabolism in male humans under general anaesthesia