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Rural development and community participation within joint planning areas : Al-Yaserreyeh case study
No full textPolycentricity as a spatial model for regional development : the case of Ramallah governorate
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Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain
No full textJournal of Lipid Research, Volume 55, 2014Ceramide (Cer) is involved in the regulation of
several cellular processes by mechanisms that depend on
Cer-induced changes on membrane biophysical properties.
Accumulating evidence shows that Cers with different N -
acyl chain composition differentially impact cell physiology,
which may in part be due to specific alterations in membrane
biophysical properties. We now address how the
sphingolipid (SL) N-acyl chain affects membrane properties
in cultured human embryonic kidney cells by over expressing
different Cer synthases (CerSs). Our results show an increase
in the order of cellular membranes in CerS2-transfected
cells caused by the enrichment in very long acyl chain SLs.
Formation of Cer upon treatment of cells with bacterial
sphingomyelinase promoted sequential changes in the properties
of the membranes: after an initial increase in the
order of the fluid plasma membrane, reorganization into
domains with gel-like properties whose characteristics are
dependent on the acyl chain structure of the Cer was observed.
Moreover, the extent of alterations of membrane
properties correlates with the amount of Cer formed.
These data reinforce the significance of Cer-induced changes
on membrane biophysical properties as a likely molecular
mechanism by which different acyl chain Cers exert their
specific biological actions.—Pinto, S. N., E. L. Laviad, J.
Stiban, S. L. Kelly, A. H. Merrill, Jr., M. Prieto, A. H. Futerman,
and L. C. Silva. Changes in membrane biophysical properties
induced by sphingomyelinase depend on the sphingolipid
N-acyl chain. J. Lipid Res. 2014. 55: 53–6
المقاومة الشعبية بعد الإنتفاضة الثانية
No full textTabar,Linda:تقدم هذه الدراسة قراءة نقدية للتجارب المختلفة للمقاومة الشعبية محللة افتقارها إلى الرؤية السياسية الشاملة التي تضع الفعل الذي يقوم به الناشطون في إطار مقاومة المشروع الكولونيالي الإسرائيلي، كما تحلل آليات المقاطعة وأثر "الربيع العربي" في الحراك الشبابي في فلسطي
No full textVarious formulations of pseudo second-order rate equations have been widely used in elucidating the rate
constants of a wide variety of sorption systems. In this paper, it is shown that a new formulation can be
obtained by making use of the mass balance equation of a single stage batch-type system. Two linear forms
of the equation were then used to analyze different sets of kinetic data. It is shown that the adequacy of
kinetic models should not be linked solely to linear correlation coefficient
