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Whole Image Synthesis Using a Deep Encoder-Decoder Network
The synthesis of medical images is an intensity transformation of a given modality in a way that represents an acquisition with a different modality (in the context of MRI this represents the synthesis of images originating from different MR sequences). Most methods follow a patch-based approach, which is computationally inefficient during synthesis and requires some sort of ‘fusion’ to synthesize a whole image from patch-level results. In this paper, we present a whole image synthesis approach that relies on deep neural networks. Our architecture resembles those of encoder-decoder networks, which aims to synthesize a source MRI modality to an other target MRI modality. The proposed method is computationally fast, it doesn’t require extensive amounts of memory, and produces comparable results to recent patch-based approaches
Model-based evaluation of scientific impact indicators
Using bibliometric data artificially generated through a model of citation dynamics calibrated on empirical data, we compare several indicators for the scientific impact of individual researchers. The use of such a controlled setup has the advantage of avoiding the biases present in real databases, and it allows us to assess which aspects of the model dynamics and which traits of individual researchers a particular indicator actually reflects. We find that the simple average citation count of the authored papers performs well in capturing the intrinsic scientific ability of researchers, regardless of the length of their career. On the other hand, when productivity complements ability in the evaluation process, the notorious h and g indices reveal their potential, yet their normalized variants do not always yield a fair comparison between researchers at different career stages. Notably, the use of logarithmic units for citation counts allows us to build simple indicators with performance equal to that of h and g. Our analysis may provide useful hints for a proper use of bibliometric indicators. Additionally, our framework can be extended by including other aspects of the scientific production process and citation dynamics, with the potential to become a standard tool for the assessment of impact metrics
Entangling Credit and Funding Shocks in Interbank Markets
Credit and liquidity shocks represent main channels of financial contagion for interbank lending markets. On one hand, banks face potential losses whenever their counterparties are under distress and thus unable to fulfill their obligations. On the other hand, solvency constraints may force banks to recover lost fundings by selling their illiquid assets, resulting in effective losses in the presence of fire sales—that is, when funding shortcomings are widespread over the market. Because of the complex structure of the network of interbank exposures, these losses reverberate among banks and eventually get amplified, with potentially catastrophic consequences for the whole financial system. Inspired by the recently proposed Debt Rank, in this work we define a systemic risk metric that estimates the potential amplification of losses in interbank markets accounting for both credit and liquidity contagion channels: the Debt-Solvency Rank. We implement this framework on a dataset of 183 European banks that were publicly traded between 2004 and 2013, showing indeed that liquidity spillovers substantially increase systemic risk, and thus cannot be neglected in stress-test scenarios. We also provide additional evidence that the interbank market was extremely fragile up to the global financial crisis, becoming slightly more robust only afterwards
Topology simulation and contact mechanics of bifractal rough surfaces*
A numerical method to generate bifractal surfaces due to a modification of the slope of the power spectral density function in the low- or high-frequency range is proposed. The method has been applied to simulate real surfaces of Ginkgo Biloba leaf scanned at two different magnifications by matching the corresponding experimental power spectral densities. Slight differences have been found in the statistical distributions of the asperity heights and curvatures for the lowest magnification that had marginal influence on the frictionless normal contact response of the surface. For highest magnification, however, the statistics of the simulated numerical surface were quite different from those of the real one, leading also to a significant difference in the normal contact results
A Quadratic Programming Algorithm Based on Nonnegative Least Squares with Applications to Embedded Model Predictive Control
This paper proposes an active set method based on nonnegative least squares (NNLS) to solve strictly convex quadratic programming (QP) problems, such as those that arise in Model Predictive Control (MPC). The main idea is to rephrase the QP problem as a Least Distance Problem (LDP) that is solved via a NNLS reformulation. While the method is rather general for solving strictly convex QP’s subject to linear inequality constraints, it is particularly useful for embedded MPC because (i) is very fast, compared to other existing state-of-theart QP algorithms, (ii) is very simple to code, requiring only basic arithmetic operations for computing LDLT decompositions recursively to solve linear systems of equations, (iii) contrary to iterative methods, provides the solution or recognizes infeasibility in a finite number of steps
Comparative Regional Integration: Governance and Legal Models
Comparative Regional Integration: Governance and Legal Models is a groundbreaking comparative study on regional or supranational integration through international and regional organizations. It provides the first comprehensive and empirically based analysis of governance systems by drawing on an original sample of 87 regional and international organizations. The authors explain how and why different organizations select specific governance processes and institutional choices, and outline which legal instruments – regulatory, organizational or procedural – are adopted to achieve integration. They reveal how different objectives influence institutional design and the integration model, for example a free trade area could insist on supremacy and refrain from adopting instruments for indirect rule, while a political union would rather engage with all available techniques. This ambitious work merges different backgrounds and disciplines to provide researchers and practitioners with a unique toolbox of institutional processes and legal mechanisms, and a classification of different models of regional and international integration
Supervised Learning of Functional Maps for Infarct Classification
Our submission to the STACOM Challenge at MICCAI 2015 is based on the supervised learning of functional map representation between End Systole (ES) and End Diastole (ED) phases of Left Ventricle (LV), for classifying infarcted LV from the healthy ones. The Laplace-Beltrami eigen-spectrum of the LV surfaces at ES and ED, represented by their triangular meshes, are used to compute the functional maps. Multi-scale distortions induced by the mapping, are further calculated by singular value decomposition of the functional map. During training, the information of whether an LV surface is healthy or diseased is known, and this information is used to train an SVM classifier for the singular values at multiple scales corresponding to the distorted areas augmented with surface area difference of epicardium and endocardium meshes. At testing similar augmented features are calculated and fed to the SVM model for classification. Promising results are obtained on both cross validation of training data as well as on testing data, which encourages us in believing that this algorithm will perform favourably in comparison to state of the art methods
Automatic Classification of Leading Interactions in a String Quartet
The aim of the present work is to analyze automatically the leading interactions between the musicians of a string quartet, using machine learning techniques applied to nonverbal features of the musicians behavior, which are detected through the help of a motion capture system. We represent these interactions by a graph of influence of the musicians, which displays the relations is following and is not following with weighted directed arcs. The goal of the machine learning problem investigated is to assign weights to these arcs in an optimal way. Since only a subset of the available training examples are labeled, a semisupervised support vector machine is used, which is based on a linear kernel to limit its model complexity. Specific potential applications within the field of human-computer interaction are also discussed, such as e-learning, networked music performance, and social active listening
A synergy-based hand control is encoded in human motor cortical areas
How the human brain controls hand movements to carry out different tasks is still debated. The concept of synergy has been proposed to indicate functional modules that may simplify the control of hand postures by simultaneously recruiting sets of muscles and joints. However, whether and to what extent synergic hand postures are encoded as such at a cortical level remains unknown. Here, we combined kinematic, electromyography, and brain activity measures obtained by functional magnetic resonance imaging while subjects performed a variety of movements towards virtual objects. Hand postural information, encoded through kinematic synergies, were represented in cortical areas devoted to hand motor control and successfully discriminated individual grasping movements, significantly outperforming alternative somatotopic or muscle-based models. Importantly, hand postural synergies were predicted by neural activation patterns within primary motor cortex. These findings support a novel cortical organization for hand movement control and open potential applications for brain-computer interfaces and neuroprostheses