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    Haemoperitoneum Due to Spontaneous Rupture of a Liver Metastasis

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    Spontaneous rupture of a liver metastasis is a life-threatening complication of metastatic liver disease. Although metastatic liver lesions are much more common than primary tumours, spontaneous rupture of a liver metastasis is rare. Therapeutic decisions must take into account the extent of metastatic liver disease and the patient’s performance status. Transarterial embolization may be considered in cases of ongoing haemorrhage despite initial conservative measures. We describe a case of haemoperitoneum due to spontaneous rupture of a liver metastasis in a 72-year-old patient with carcinoma of unknown origin who responded well to conservative management

    Adding Herbal Products to Direct-Acting Oral Anticoagulants Can Be Fatal

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    Direct-acting oral anticoagulants (DOACs) are used to prevent and treat systemic and cerebral embolisms in patients with non-valvular atrial fibrillation (NV-AF). The use of DOACs with herbal products without consulting healthcare professionals increases the possibility of drug–herb interactions and their adverse effects. An 80-year-old man on dabigatran with a known history of NV-AF presented with a 1-day history of haematemesis and black stool which began 3 days after he had started taking a boiled mixture of ginger and cinnamon. The patient was hypotensive and treated as a case of gastrointestinal bleeding and haemorrhagic shock. Despite continuous aggressive resuscitation measures including administration of a reversal agent for dabigatran, we were unable to control bleeding and the patient died within 24 hours. The interaction of ginger and cinnamon with dabigatran led to fatal bleeding

    Mandibular Osteonecrosis Associated with Antacid Therapy (Esomeprazole)

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    Introduction: Osteonecrosis of the jaw has been consistently reported in the literature associated to the high-dose intravenous bisphosphonate therapy. However, osteonecrosis can also occur in patients who have other risk factors. Case description: An unusual case of ONJ in a patient being treated with esomeprazole is reported. Discussion: The probable association between proton pump inhibitor intake and osteonecrosis of the jaw should alert clinicians. Collaborations between medical and dental doctor and an early diagnosis might prevent or reduce the morbidity resulting from advanced destructive lesions of the jaw bone

    Catastrophic Gastrointestinal Bleeding: Always Consider Meckel’s Diverticulum

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    Meckel’s diverticulum, a congenital malformation of the gastrointestinal tract, is asymptomatic in the majority of patients but can be associated with some complications. Gastrointestinal bleeding is one such complication and is more common in children than in adults. Despite the variety of examinations available, diagnosis can be difficult, especially in older patients, because the sensitivity of examinations decreases with patient age. Here we present the case of a young man with gastrointestinal bleeding in whom a diagnosis of Meckel’s diverticulum was made intra-operatively

    IAEA activities in support of accelerator-based research and applications

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    Accelerator applications is one of the thematic areas, where the IAEA Physics Section supports IAEA Member States in strengthening their capabilities to adopt and benefit from the use of accelerators. A number of activities are being implemented by the IAEA Physics Section focusing on accelerator-based applications in multiple disciplines, facilitation of access to accelerator facilities, organization of meetings, coordination of joint research projects and capacity building in accelerator-based technologies and techniques. This communication reports on the currently implemented activities together with those planned for the near future

    Gamma energy evaluation for creation of 111mCd, 113mIn, and 115mIn isotopes

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    NASA Glenn Research Center is investigating nuclear reactions in deuterated materials exposed to bremsstrahlung photons with kinetic energies from 1-3 MeV. Recent experiments used a continuous beam Dynamitron electron accelerator with a braking target. Electron beam energy loss verification was desired and experiments using cadmium and indium were completed which are known to transition to excited metastable states after exposure to bremsstrahlung photons. The gamma spin-up of 111Cd, 113In, and 115In are with photon beam energies of 1017 keV, 1024 keV, and 941 keV respectively. Recent tests corroborated published gamma energies using a beam energy loss of 62 to 74 keV

    Low-energy Coulomb excitation of 94Zr

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    Recent state-of-the-art Monte Carlo shell-model calculations predict shape coexistence in Zr isotopes. In this context, the 94Zr nucleus is particularly interesting since some experimental investigations have already suggested the possible coexistence of spherical and oblate shapes, however, no definitive conclusion on its deformation has been reported to date. As such, a dedicated experiment to study collectivity and configuration coexistence in 94Zr by means of a low-energy Coulomb excitation was performed. This study was performed at the INFN Legnaro National Laboratory with the GALILEO-SPIDER setup, which, in this instance, was further augmented with 6 Lanthanum Bromide scintillators (LaBr3:Ce) in order to to maximize the γ-ray detection efficiency

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    The g − 2 experiment

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    This paper briefly describes the main features of the muon g − 2 experiment E989 at Fermilab. The experiment aims to measure the muon anomaly with a 140 ppb accuracy, improving by a factor 4 last measurement done at BNL (E821), and potentially revealing new physics beyond the Standard Model

    The Critical Science Plan for DKIST

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    The 4-meter Daniel K. Inouye Solar Telescope is nearing completion on Haleakala, Maui, with first light expected in 2020. In preparation for early science, the National Solar Observatory is reaching out to the solar community in order to define the critical science goals for the first two years of DKIST operations. The overall aim of this “Critical Science Plan” is to be ready, by start of operations, to execute a set of observations that take full advantage of the DKIST capabilities to address critical compelling science

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