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Il recupero del genius loci del sito archeologico di Ghoufi (Aurès, Wilaya de Batna, Algeria)
Get PDFGhoufi is located in the Aurès Valley, near the ‘Oued El Abiod’. Its location, next to the panoramic road RN31, is referred to as ‘Balcon de Ghoufi’ because - from above - you can perceive the depth of the canyon (500/1200 m) and the beauty of the place, scattered with Berber villages (vernacular semitrogloditic architecture), terracing, water collection systems, palm groves, orchards and gardens. The Aurès Valley - a thoroughfare since ancient times, a caravan route between the desert and the Mediterranean Sea - has been the subject of archaeological explorations by Pierre Morizot since 1957-1962, which established the chronology of the settlements. This valuable work has been supplemented by ongoing research. This territory still retains the morphological and hydrographic peculiarities that justify the Berber settlement choice despite the fact that unfortunately the places have been abandoned following a recent flood. From 2016 activities of survey and research, directed by the University Badji Mokhtar of Annaba and the Polytechnic of Milan resumed at Ghoufi. These activities are aimed in particular at surveying archaeological and architectural artefacts, conservation interventions to address deterioration and instability and valorisation projects. Since 2017 the research has been funded by the MAECI. The project begun with the collection of documentation and knowledge of the Ghoufi site in a GIS environment. It prefigured a preliminary scenario for its conservation and reuse, following an approach of archaeological sustainability respectful of the characteristics of the site, the territory and the Country
The shape of colour. The cave of San Michele on Monte Tancia (Italy)
Get PDFStarting from the indications derived from the cartographic representation, the goal of the research project described in this paper was to experiment with different tests on the frescoed surfaces of rock-cut architecture for the visualization of the real shape of the subject. For the first time a 3D survey was carried out by the authors in the cave of San Michele on Monte Tancia to test different techniques of processing the numerical models in order to achieve the plane representation of random surfaces, including those with the frescoed plaster. This activity is part of a broader research program related to the investigation of rupestrian architecture, addressing problems of data representation
Skeletal Myopathy as the Initial Manifestation of Light Chain Multiple Myeloma
Get PDFMonoclonal gammopathies due to plasma cell dyscrasias can cause various rare neuromuscular disorders. The peripheral nervous system is most commonly affected, while muscle diseases associated with monoclonal gammopathies are rare. Skeletal myopathy, as a manifestation in the context of multiple myeloma, is extremely uncommon and is usually the result of immunoglobulin light chain (AL) amyloidosis deposits in the muscles. Here we present an atypical case of a patient with generalized myopathy as the presenting manifestation of light chain multiple myeloma. Interestingly, muscle involvement in our case was not the consequence of AL amyloidosis deposits but rather due to non-amyloid light chain deposition disease associated with light chain multiple myeloma
An Unusual Association: Takayasu’s Arteritis and Tubulointerstitial Nephritis and Uveitis Syndrome
Get PDFThe coexistence of two immune-mediated diseases in the same patient is unusual. Takayasu’s arteritis (TA), which is a chronic granulomatous vasculitis, was discovered in a 47-year-old woman followed for tubulointerstitial nephritis and uveitis syndrome (TINU syndrome). We present the first case of this association
Spontaneous Splenic Rupture in an Ill Returned Traveller
Get PDFSpontaneous splenic rupture is a known, but rare and possibly fatal, complication of different infectious diseases. We present a case of a 38-year-old male patient who presented with fever, icterus and spontaneous splenic rupture after a visit to Vietnam and discuss the differential diagnosis of splenic rupture in ill returned travellers
Sinonasal Chondrosarcoma, an Unusual Location
Get PDFIntroduction: Chondrosarcoma is a tumour with a cartilaginous matrix frequently encountered in long bones and the pelvis with rare sinonasal location.Patient and methods: We report the case of a 25-year-old patient who was referred to us for an extension work-up for sinonasal chondrosarcoma confirmed by anatomopathological examination.Results: Facial magnetic resonance imaging (MRI) confirmed by a CT scan showed an osteolytic tumour process of the hard palate and walls of the left maxillary sinus that was locally advanced.Conclusion: The sinonasal location of a chondrosarcoma is rare. Characterized by cross-sectional imaging, confirmation was provided by histological assessment
Obiezione di coscienza, cooperazione al male e vaccini anti-Covid
Get PDFL’articolo prende in esame il problema dell’obiezione di coscienza in ambito sanitario dal punto di vista di un particolare argomento morale centrato sulla “complicità” o, in termini teologici, sulla “cooperazione materiale al male”. Il testo prende spunto da un recente controversia che riguarda lo sviluppo di vaccini anti-Covid19 a partire da terreni di coltura formati grazie a cellule ricavate da feti abortiti. Secondo alcuni, queste cellule sono “macchiate”
dal male originario dell’aborto e, pertanto, chiunque ne utilizzasse i prodotti si renderebbe materialmente complice di quel male. L’articolo mette quindi in luce l’ampio uso che nell’ultimo decennio si è fatto di questo argomento morale centrato sulla complicità per tentare di estendere il
ricorso all’obiezione di coscienza in ambito sanitario e non solo. Infine, l’articolo si conclude sottolineando la necessità di raggiungere “compromessi di alto profilo" come unica via possibile per consentire la pacifica convivenza di stili di vita morale differenti all’interno di una forma di
Stato ispirata ai principii del pluralismo morale e della laicità
Anosmia and Dysgeusia in the Absence of Other Respiratory Diseases: Should COVID-19 Infection Be Considered?
Get PDFWe describe two elderly patients evaluated at emergency departments for anosmia/dysgeusia in the absence of any other respiratory symptoms prior to or upon admission. In the current epidemiological context, clinical and biological work-up led to a diagnosis of COVID-19 infection. Unfortunately, one of the patients died during hospitalization, but the other recovered and was discharged
Co-infection with Influenza A and COVID-19
Get PDFCOVID-19, also called severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2), originated in Wuhan, China. It has caused significant morbidity and mortality worldwide and has been declared a global pandemic by the WHO. Influenza occurs mainly during the winter, with the burden of disease determined by several factors, including the effectiveness of the vaccine that season, the characteristics of the circulating viruses, and how long the season lasts. We describe the case of a 66-year-old woman who was diagnosed with influenza A and COVID-19 co-infection
Tocilizumab in Severe COVID-19 Pneumonia and Concomitant Cytokine Release Syndrome
Get PDFYounger patients with COVID-19 may experience an exaggerated immune response to SARS-CoV-2 infection and develop cytokine release syndrome (CRS), which may be life threatening. There is no proven antiviral therapy for COVID-19 so far, but profound immunosuppression has recently been suggested as a treatment for COVID-19-associated CRS. We present a case of life-threatening CRS caused by COVID-19 infection with a favourable response to immunosuppressive therapy with tocilizumab (TCZ). The rapid clinical and biochemical improvement following TCZ administration suggests that treatment with immunotherapy can be life-saving in selected patients with COVID-19-induced CRS