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Cladosporium herbarum Hot-Tub Lung Hypersensitivity Pneumonitis in a Greenhouse Worker
Get PDFHypersensitivity pneumonitis is understood to be a delayed allergic reaction to the repeated exposure of a usually innocent inhaled agent, causing inflammatory damage to the pulmonary parenchyma, alveoli and terminal bronchioles. With ongoing exposure, it can cause respiratory compromise and pulmonary fibrosis. Recognizing the heterogeneity of the causative agents and the low incidence of the disease, we considered it important to report the case of a greenhouse worker who developed aCladosporium sp. related hot-tub lung hypersensitivity pneumonitis. We believe it to be the first reported case of a greenhouse occupational hypersensitivity pneumonitis due to Cladosporium sp
Composizione specifica del megabenthos non commerciale della comapagna MEDITS 2018 - GSA 16 (Sicilia meridionale)
Get PDFLa presente Relazione Tecnica ha lo scopo di fornire informazioni sulla composizione specifica delle comunità megabentoniche campionate durante la campagna di pesca a strascico sperimentale MEDITS, effettuata nella GSA 16 nell’estate del 201
Inhaled Tranexamic Acid for Non-Massive Haemoptysis in a Rivaroxaban-Receiving Patient Not Responding to the Oral Fo
Get PDFHaemoptysis is the expectoration of blood originating from the respiratory tract and occurs secondary to infection, malignancy, bronchiectasis or vascular disease. Its severity varies from minimal blood-streaked sputum to life-threatening haemorrhage. Therefore, prompt evaluation of the cause of the haemoptysis and its severity, and timely management are crucial. Although there is still no effective therapy for haemoptysis apart from treating the cause, inhaled tranexamic acid (TXA) might have a potential role in controlling non-massive haemoptysis. Here, we present a case of non-massive haemoptysis in a COPD patient with bronchiectasis on rivaroxaban for atrial fibrillation who responded to inhaled TXA following a failed trial of the oral formulation
Unusual Location of a Recurrent Epidermoid Cyst
Get PDFIntroduction: Epidermoid cysts of the temporal bone are rare, benign and slow-growing lesions. Patient and Methods: We report the case of a 69-year-old female patient followed up for a symptomatic intradiploic epidermoid cyst of the temporal scale and left mastoid region, which had been operated on but recurred.Results: MRI demonstrated a well-limited lesion seen as a hyposignal on T1-weighted images, hypersignal on T2-weighted images, on FLAIR and on diffusion-weighted images not enhanced by gadolinium. The tumour was compressive, and bone lysis was seen on CT.Conclusion: Epidermoid cysts of the temporal bone are rare, benign lesions whose diagnosis is based on fluid signals seen on MRI but absent on FLAIR sequences
First Test of an Automated Detection Platform to Identify Risk of Decompensation in Elderly Patients
Get PDFIntroduction: We tested the MyPrediTM e-platform which is dedicated to the automated, intelligent detection of situations posing a risk of decompensation in geriatric patients.Objective: The goal was to validate the technological choices, to consolidate the system and to test the robustness of the MyPrediTM e-platform through daily use. Results: The telemedicine solution took 3,552 measurements for a hospitalized patient during her stay, with an average of 237 measurements per day, and issued 32 alerts, with an average of 2 alerts per day. The main risk was heart failure which generated the most alerts (n=13). The platform had 100% sensitivity for all geriatric risks, and had very satisfactory positive and negative predictive values.Conclusion: The present experiment validates the technological choices, the tools and the solutions developed
Simultaneous Presentation of Parvovirus B19 Infection and Systemic Lupus Erythematosus in a Patient: Description and Review of the Literature
Get PDFWe present the case of a 25-year-old woman without medical history, presenting with acute respiratory failure needing mechanical ventilation. Aetiologic screening showed PVB19 primary infection and concomitant SLE flare-up. We discuss the causative interactions between PVB19 and SLE in the pathogenesis of the disease. Difficulty diagnosing inaugural SLE flare-up concomitant with PVB19 infection can lead to delayed diagnosis and treatment. Inversely, overtreating a SLE-mimicking PVB19 infection with immunosuppressive agents can be highly detrimental
Bariatric Surgery can Lower the Efficacy of DOACs
Get PDFA 39-year-old woman who was taking the contraceptive pill was admitted with right leg deep venous thrombosis (DVT). She was started on apixaban tablets, but after 8 days developed proximal progression of the DVT and pulmonary embolism. Her medical history later showed a history of sleeve gastrectomy. The patient responded to a vitamin K antagonist after heparin. The failure of the antithrombotic drug shed light on the efficacy and changed pharmacodynamics of direct oral anticoagulants (DOACs) after bariatric surgery in the absence of commercially available blood monitoring tests
Variegate Porphyria Triggered by Acute Hepatitis A Infection
Get PDFBackground: Variegate porphyria (VP) is a rare disorder of haem biosynthesis. We report a novel association with hepatitis A infection.Patient and methods: A 31-year-old man was diagnosed with acute hepatitis A infection. During recovery, he presented with abdominal pain and a photoaggravated blistering skin eruption.Results: Urine porphyrin precursors were markedly raised with high coproporphyrin III isomer levels. Faecal protoporphyrin levels were markedly increased and a maximum plasma fluorescence emission at 629 nm was noted. Discussion: Acute hepatitis A infection, and the associated metabolic stress exerted on the haem biosynthetic pathway, induced overt presentation of latent VP
Recent developments in fast timing ASICs for particle physics and medical imaging
Get PDFThis paper will cover recent developments and trends in ASICs designed by Weeroc and its affiliated laboratory, OMEGA (IN2P3/CNRS/Ecole Polytechnique), for medical imaging and particle physics applications. Two categories of ASIC will be reviewed: ASICs for medical imaging (e.g., TOF-PET) which have been designed for obtaining the lowest CTR (sub 100 ps RMS) and ASICs in particles physics which are driven by readout of fast silicon sensors in the HL-LHC upgrade program
Charged particle identification using time of flight with FAZIA
Get PDFThis contribution reports on the time of flight implementation in the FAZIA Si-Si-CsI(Tl) telescopes, focusing on the basic ideas of the method and on some results from recent experiments at LNS