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    La filosofia della scienza ai tempi della pandemia Covid-19

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    Il testo del comitato etico della Fondazione Veronesi si interroga su questioni fondamentali e urgenti, soprattutto considerato che, a quasi due anni dall'inizio della pandemia Covid-19, non possiamo dire esserne ancora fuori. Il testo presenta dinamiche e problemi della scienza, nella realtà molto complessi, in modo estremamente accessibile e informativo. Le dinamiche della scienza, in questo caso delle scienze della salute, presentano molte complessità anche dal punto di vista dell'analisi filosofica. Esiste un intricato intreccio di questioni metodologiche, epistemologiche e ontologiche, normative. Queste dimensioni operano sia al li- vello della produzione scientifica sia al livello della decisione e implementazione delle politiche sanitari

    Recensioni: La malattia da 10 centesimi. Storia della polio e di come ha cambiato la nostra società

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    Non c'è legame tanto fedele come quello fra l'umanità e la malattia. «In ogni atto medico ci sono sempre due parti coinvolte, il medico e il paziente, o, in un senso più ampio, il corpo sanitario e la società» scriveva ottant'anni fa Henry E. Sigerist, all'epoca direttore del Johns Hopkins Institute of Medical History. «La storia della medicina diventa così storia sociale». “La malattia da 10 centesimi” di Agnese Collino non tradisce questa traccia. Il volume è una storia della poliomielite «e di come ha cambiato la nostra società». Agnese Col- lino, biologa molecolare e divulgatrice scientifica, racconta una malattia che ha segnato una parte importante della scienza e la società durante il secolo scorso e che oggi si colloca ancora in una posizione di passaggio, fra generazioni che ne ricordano la minaccia e altre per cui è probabilmente poco più concreta della peste manzoniana (a meno che abbiano letto Philip Roth a scuola). E lo fa in un momento storico particolare, quello della pandemia di Covid-19, il brusco risveglio del mondo industrializzato che sembrava avere rimosso le malattie infettive dal suo orizzonte

    Spina e rosa: il volgarizzamento italiano del Compendium theologicae veritatis di Ugo Ripelin di Strasburgo OP

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    Hugo Ripelin of Strasburg’s Compendium theologicae veritatis was an extremely popular work of theological instruction in the Late Middle Ages. An Italian version of its third and fifth book, dealing with the vices and the virtues, is headed Spina e Rosa. This vernacular treatise had also remarkable success, especially during the 15th century. The paper presents its manuscript tradition, which amounts to 20 copies. Whereas most of them are of Northern Italian origin, the oldest ms. and some other testimonies as well, come from Central- Southern Italy, leaving open the question about the origin of the text. Yet, the content and provenience of the mss. confirm that Spina e Rosa, written during the 14th century, belongs entirely to the contemporary culture of religious volgarizzamenti as established by the Tuscan Dominicans. Furthermore, it can be shown that this vernacular version of the Compendium was widespread among Franciscan and Augustine Friars

    Mesoporous silica particles functionalized with newly extracted fish oil (Omeg@Silica) inhibit lung cancer cell growth

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    Aim: To assess whether Omeg@Silica microparticles - fish oil from anchovy fillet leftovers (AnchoisOil) encapsulated within mesoporous silica particles - are effective in promoting antitumor effects in lung cancer cells. Methods: Three human non-small-cell lung cancer cell lines (A549, Colo 699 and SK-MES-1) were used. Cells were treated with AnchoisOil dispersed in ethanol or encapsulated in silica and further formulated in aqueous ethanol. Cell cycle, reactive oxygen species, mitochondrial stress and long-term proliferation were assessed. Results & conclusion: Omeg@Silica microparticles were more effective than fish oil in increasing reactive oxygen species and mitochondrial damage, and in altering the cell cycle and reducing cell proliferation, in lung cancer cells. These in vitro antitumor effects of Omeg@Silica support its investigation in lung cancer therapy

    Understanding the effect of trampling in a spatial perspective: a case study from a long-lived-in dwelling space of the Bronze Age settlement of Coppa Nevigata (South-Eastern Italy)

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    Long-lived-in dwelling spaces provide a huge number of valuable data by which to figure out human activities and patterns of space use by prehistoric communities. However, cultural dynamics can intervene during deposit formation processes and transform depositional sets of rubbish involving artefacts and ecofacts. Notably, trampling resulting from human activities represents the most intrusive agent that affects spaces continuously used over a certain timespan. Therefore, comprehending the effect of trampling represents a key-step to assess the distribution of items in the archaeological record and to establish a solid base on which to build valid models of the use of space. This paper proposes a methodological approach to figure out the diverse effects of trampling. The methodology has been tailored on a specific case study, a long-lived-in dwelling area of the Bronze Age settlement of Coppa Nevigata (South-Eastern Italy), dated to the 12th cent. BC. Here, cycles of use and of the discarding of pottery produced a massive number of shards, whose primary deposition has been probably subjected to alteration by trampling. On this premise, the impasto pottery record has been considered as viable proxy to investigate the effects of this cultural agent on the archaeological record. The analysis proceeds by three main steps: a data entry process structured to optimize the recording of shards dimension, fragmentation rate analysis of shards and spatial analysis of well-preserved vessels. This integrated approach allowed an assessment of the reliability of distribution and conservation of the archaeological record in the studied spaces, providing crucial information to better understand use of space patterns through a second analytical step: spatial analysis of artefacts and ecofacts. An aim of this paper is to provide an analytical process replicable for further Late Prehistoric contexts

    La statua ritrovata. Identificazione, analisi e proposta di ricostruzione virtuale di una scultura conservata presso il Museo Egizio di Torino

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    This article illustrates a case study from an ongoing research project on the statues and sculptural fragments from Tebtynis, discovered by Carlo Anti during the 1930-1936 excavation campaigns, in the temple dedicated to the god Soknebtynis. Specifically, it examines a non-royal statue which one of the authors has recently identified as Turin, Museo Egizio S. 19400+S. 19400/1. The authors combine a study of relevant archival records currently kept in Padua and Venice, Italy, with the virtual reconstruction of the fragment of the head and the stylistic analysis of the statue in order to shed light on the sculpture and retrace its post-excavation histor

    IT applications to archaeology and the OA diamond journals’ challenge. Enhancing access and reuse of textual and visual resources

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    Open Science best practices and policies have been increasingly promoted and adopted in Europe and worldwide to extend public availability of research data and publications, according to FAIR principles. In this context, the so-called ‘Diamond Open Access’ model is particularly relevant since it entails provision of scientific content entirely free of charge, both for authors and readers. The journal Archeologia e Calcolatori adopted this model at a very early stage, when - in 2005 - it started publishing online full-text PDFs and metadata of its articles according to recognised standards, as an Open Archives Initiative data provider. This paper addresses the evolution of ‘Archeologia e Calcolatori’ in the context of scientific publishing in the disciplinary domain of IT applications to archaeology. It focuses on the updates of its OAI-PMH repository, which led to the journal’s inclusion in OpenAIRE as a data provider, and on mapping its current position in the OA Diamond landscape. The paper also illustrates recent implementations of Archeologia e Calcolatori’s website to provide full access to visual and interactive resources, such as images and 3D models, related to its publications, and to relevant metadata, structured according to OpenAIRE’s most recent guidelines. The combined, contextual provision of full texts, visual and interactive resources, and structured metadata – including full annotations and relations turns out to be a pioneering publishingservice in the domain of IT applications to archaeology

    Searching for ancient sonic experience in present-day landscapes

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    Research on ancient sensory experience has questioned ocular-centric research as the primary form of knowledge production in archaeological investigations. With enough information about the material composition of an ancient building, the acoustic properties of the interior spaces can be modeled for greater understanding of the daily experience of past users. Acoustics can reveal what people heard in the past, an experiential starting point to begin asking how someone heard in the past. Thus, acoustic study of place offers the potential to deepen understanding of the emplaced past experience as well as limitations to what conclusions can be drawn directly from gathered data. One area that remains underdeveloped is the research of sounded experience in ancient outdoor settings. This paper presents ongoing acoustic research at the ancient Greek sanctuary to Zeus on Mount Lykaion, applying psychoacoustic analysis to comprehensive recording efforts. Moments of sonic connectivity and isolation in this mountainous site align with past building outlines and prominent landscape features, suggesting that the sanctuary landscape likely played a key role in ritual experiences. The sonic dynamics of the landscape can still be experienced and measured today. The paper details the current approach to data collection and analysis on the mountain and includes some of the challenges afforded by applying acoustic study in the ancient built landscape

    Virtual Archaeology and the study of necropolises as a system: methodology and practice in the case study of Numana (AN), Italy, in Baldoni V. (ed.), From Pottery to Context. Archaeology and Virtual Modelling

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    The paper briefly introduces methodologies and practices of Virtual Archaeology applied to the pre-Roman funerary contexts of Numana (Ancona). Starting from the traditional approach and the concept of necropolis as a system, we will focus on the methodological issues and potentialities related to the use of digital models for the archaeological analysis of grave goods and their contexts

    Quick digitization techniques: the case study of Numana necropolis, in Baldoni V. (ed.), From Pottery to Context. Archaeology and Virtual Modelling

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    The general digital reconstruction of the necropolis in Numana was carried on following a methodology targeted to a quick survey at different scales: from the single ceramic or artifact to the whole archaeological landscape. Fostering the application of common computer graphics techniques, an easily replicable process was set up, in order to produce 3D models mainly adopted for archaeological analysis and collection of data that could have been acquired in different times, with different approaches

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