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Azygos Continuation of the Inferior Vena Cava:Potential for Misdiagnosis as Lung Neoplasm
Background:
The azygos venous system is an accessory venous pathway supplying an important collateral circulation between the superior and inferior vena cava (IVC).
Case summary:
We report a case of complicated community-acquired pneumonia with interruption of the IVC with azygos continuation that
was misdiagnosed as lung neoplasm.
Discussion:
The aim of this case report is to emphasize the importance of recognizing an enlarged azygos vein at the confluence with the superior vena cava and in the retrocrural space to avoid misdiagnosis as a right-sided para-tracheal mass. The angiographic features and clinical importance of this condition are discussed
Il Centro CISAS "Centro Internazionale di Studi Avanzati su Ambiente, Ecosistema e Salute Umana
Il progetto CISAS, "Centro internazionale di studi avanzati su ambiente ed impatti su ecosistema e salute umana", finanziato con fondi del Fondo integrativo speciale per la ricerca (FISR) 2014 - 2015, articolo 2, comma 1, lettera b) Decreto legislativo 5 giugno 1998, n. 204, Delibera CIPE n. 105/2015 del 23 dicembre 2015, nell'ambito delle attività del Work Package 1 “Coordinamento, gestione e comunicazione”, ha previsto la creazione del Centro internazionale di studi avanzati su ambiente ed impatti su ecosistema e salute umana attraverso l'individuazione di spazi fisici dedicati alle attività avanzate di ricerca nell’ambito scientifico di riferimento del CNR
Introduction: an overview of how virtual reconstructions and sound simulations can improve our knowledge on ancient musical instruments and sound heritage
Introduction to the section "From digitalisation and virtual reconstruction of ancient musical instruments to sound heritage simulation and preservation
From minerals to artefacts: the role and challenges of 3D modelling
Over the past decade, we have witnessed an increase in the use of technology, through the creation of virtual itineraries and exhibitions, as a tool to guarantee and increase the usability of museums and more generally of artistic and historical works. In fact, it often happens that many works of art and artefacts of archaeological and cultural importance are not accessible to the public, either because they are kept in museum deposits or because they are difficult to access. In a context such as the current one, however, with an ongoing pandemic that forces most of the population to remain at home, the virtualization of museums, and historical and cultural heritage, becomes the main tool for exploring and enhancing culture. Among the various methodologies used for the creation of three-dimensional models, photogrammetry stands out for ease of use and low cost. This article analyses the use of photogrammetry in 3D modelling, focusing on pros and cons as a rapid, low-cost tool, which makes artworks virtually accessible to the public via museum websites and social network forums
Architectural and sculptural decoration of Roman central Adriatic Italy: an archaeological and archaeometric approach to region-wide marble trade
During the Late Republic and Early Empire, central Adriatic Italy was one of the most urbanised regions in the Roman world and most cities were extensively equipped with monumental buildings, often lavishly decorated with imported marbles and sculptures. This contribution presents the results of an archaeological and archaeometric study of the architectural and sculptural marbles used in this central Adriatic area. The determination of the geographical origin of white and polychrome marbles was carried out through macroscopic examination and laboratory investigations (optical petrography, X-ray diffraction, oxygen and carbon stable isotopes). The analyses revealed the presence of a wide range of lithotypes from Italy, Greece (mainland and Aegean islands), Asia Minor, North Africa and Egypt, including varieties of white marble from Carrara, Proconnesos, Pentelikon, Thasos, Paros and Dokimeion
Pulmonary Involvement Responsive to Enzyme Replacement Therapy in an Elderly Patient with Gaucher Disease
Type 1 Gaucher disease (GD) is a rare autosomal recessive lysosomal storage disorder caused by deficient activity of beta-glucocerebrosidase, leading to accumulation of its substrate (glucosylceramide) in macrophages of the reticuloendothelial system, which are then referred to as Gaucher cells. The most frequent symptoms are asthenia, spleen and liver enlargement, bone abnormalities and cytopenia due to bone marrow infiltration. Lung involvement in GD is a rare finding, and it is unclear whether it may regress under enzyme replacement therapy (ERT) or substrate reduction therapy (SRT). Here we report a case of type 1 GD recently diagnosed in an elderly patient complicated by infiltrative lung disease, which responded to ERT
Flavour non-universal Pati-Salam unification and neutrino masses
The B anomalies, by their distinctive flavour structure i.e. U(2)5, bring a new piece to the long-standing flavour puzzle. The three-site flavour nonuniversal Pati-Salam (PS) model, which unifies quarks and leptons, provides through
the ratios of vacuum expectation values (VEV) acquired at different scales, a combined explanation of the charged and neutral current B anomalies as well as of the mass hierarchies of the Standard Model (SM). The mixings, in new, flavour non-universal, gauge interactions, as well as in the Yukawa couplings, are obtained through suppressed nearest-neighbour interactions. In this three-site model context,
the inverse seesaw mechanism is realised, with the minimal addition of three fermion singlets S(i) L and where U(1)F fermion number is broken dynamically via new singlet
scalars Φi, yielding an anarchic light neutrino mass matrix in consistency with data, despite the U(2)5 flavour symmetry observed in the Yukawa matrices. A prediction of this model is Pontecorvo-Maki-Nakagawa-Sakata (PMNS) unitarity violation with a 33 entry close to experimental bounds. The full model finds a natural 5D interpretation with three (almost equidistant) defects in a warped extra dimension, where the exponential hierarchies in VEV ratios of the 4D Lagrangian arise from O(1) differences in the 5D field bulk masse
Study of K0S production via high-pT dihadron correlations in -pp collisions with ALICE
Complementary to jet reconstruction, two-particle correlations in Δη and Δϕ can be used to study jets, in particular, their particle composition. While in Pb–Pb
collisions, this is done to characterize the quark-gluon plasma, pp and p–Pb collisions serve as a reference and are of interest on their own for their input into the understanding of particle production mechanisms. Recent ALICE results on the production of strange particles in small systems (pp and p-Pb collisions) reveal the possibility of having similar strange hadron production mechanisms in all collision systems. We study the production mechanism of strange K0S meson in jets via two-particle correlations between the K0S and charged primary hadrons (h) in -pp collisions at √s = 13 TeV collected with the ALICE experiment at the LHC. In this paper, the per-trigger yields of K0S and charged hadrons will be presented
on both the near-side and away-side of the h-K0S and K0S- h correlation functions. These yields will be shown depending on the transverse momenta of the trigger and associated particles, as well as on the event multiplicity. Moreover, the ratios of these yields to the yields extracted from the h-h correlation function will be shown. In addition, a comparison to different MC generators will be presented, which will allow us to better understand strangeness production in jets
Measurement of the conformational switching of azobenzenes from the macro- to attomolar scale in self-assembled 2D and 3D nanostructures
It is important, but challenging, to measure the (photo)induced switching of molecules in different chemical environments, from solution through thin layers to solid bulk crystals. We compare the cis–trans conformational switching of commercial azobenzene molecules in different liquid and solid environments: polar solutions, liquid polymers, 2D nanostructures and 3D crystals. We achieve this goal by using complementary techniques: optical absorption spectroscopy, femtosecond transient absorption spectroscopy, Kelvin probe force microscopy and reflectance spectroscopy, supported by density functional theory calculations. We could observe the same molecule showing fast switching in a few picoseconds, when studied as an isolated molecule in water, or slow switching in tens of minutes, when assembled in 3D crystals. It is worth noting that we could also observe switching for small ensembles of molecules (a few attomoles), representing an intermediate case between single molecules and bulk structures. This was achieved using Kelvin probe force microscopy to monitor the change of surface potential of nanometric thin 2D islands containing ca. 106 molecules each, self-assembled on a substrate. This approach is not limited to azobenzenes, but can be used to observe molecular switching in isolated ensembles of molecules or other nano-objects and to study synergistic molecular processes at the nanoscale
TMek: A lab-on-chip diagnostic test for the malaria disease
The search for new rapid diagnostic tests is a priority in the fight against malaria, one of the most common life-threatening infectious diseases. In this paper, we present an easy to operate lab-on-chip platform that allows a panplasmodic, rapid and quantitative illness detection. This innovative system, named TMek, is based on the paramagnetic behavior of infected cells with respect to other blood components, thus allowing for a magnetophoretic separation in a high magnetic field gradient. The capability of our test to perform this selective detection has been tested by means of capture experiments on treated bovine red blood cells and suspensions of synthetic hemozoin crystals. Preliminary tests on patients with malaria were successfully done at the Sacco Hospital in Milano and the possibility to perform a follow up of the treatment has emerged. A study on the discrimination of the infection stages has been done on cultured red blood cells at Istituto Superiore di Sanit´a in Roma. In April 2019, a preclinical validation has been carried out at Hˆopital Saint Luc of Mbalmayo, in Cameroon, on 75 suspected malaria patients. Even though the number of samples was limited, this preliminary study indicates the on-field operability of TMek as a rapid diagnostic test for malaria