Universitas Ahmad Dahlan

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    10023 research outputs found

    LAPORAN PRAKTEK MAGANG Pembuatan Website E-Office Dengan Framework Laravel PT. Pesat Aghni Solusi

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    Perkembangan teknologi informasi dan komunikasi (TIK) yang semakin pesat telah membawa perubahan besar dalam berbagai aspek kehidupan, termasuk dalam bidang administrasi dan manajemen. Salah satu perubahan yang terjadi adalah dengan munculnya sistem e-office. Sistem e-office merupakan sistem administrasi dan manajemen yang berbasis teknologi informasi dan komunikasi (Herdiana & Marsofiyati, 2019). Sistem ini memungkinkan pengguna untuk melakukan berbagai aktivitas administrasi dan manajemen secara digital, mulai dari surat menyurat, pengelolaan dokumen, hingga pengelolaan keuangan (Narsen & Sugiarto, 2022). PT. Pesat Aghni Solusi adalah sebuah perusahaan IT yang bergerak di bidang pengembangan perangkat lunak. Perusahaan ini memiliki kebutuhan untuk mengembangkan sistem e-office untuk meningkatkan efisiensi dan efektivitas administrasi dan manajemen perusahaan. Pembuatan website e-office dengan framework Laravel merupakan salah satu solusi yang ditawarkan oleh PT. Pesat Aghni Solusi. Framework Laravel merupakan salah satu framework PHP yang populer dan banyak digunakan oleh pengembang web. Framework ini menawarkan berbagai fitur dan manfaat yang dapat memudahkan pengembang dalam membangun website e-office

    The Citrus sinensis peel extract’s increase HDL and reduce LDL levels in cigarette smoke-induced Rats

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    SK Mengajar dan Presensi Intructional Tech in Education

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    SK Mengajar dan Presensi Intructional Tech in Educatio

    ANALISIS PENGEMBANGAN GAME QUIZ FALSIA

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    IMPLEMENTASI WEB PROFILE PRM DAN MASJID NGERSTIHARJO SELATAN (USER INTERFACE DESIGN)

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    Program Penguatan kapasitas Ormawa Himpunan Mahasiswa Teknologi Pangan Website Rumah Bandeng

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    FRONT END DEVELOPER DALAM PEMBUATAN WEBSITE PENGGAJIAN KARYAWAN PT. PRIMA KARYA MANDIRI

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    DATA KARYA ILMIAH BERDASARKAN TOPIK KAJIAN MULAI TAHUN 2018-2023

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    Hasil cek similarity"The apoptosis induction of Zingiber oficinale ethanolic extract-treated HeLa (Human Cervical Cancer) cells and active compound profiling using gas chromatography/MASS spectrometry"

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    Cervical cancer accounts for the highest percentage of cancer-related deaths in Indonesia, accounting for nearly 60% of all cancer cases. Therefore, research into the anticancer mechanisms needs to be conducted. The ethanolic extract of Zingiber officinale (EEZO) contains zingiberene, a chemical known for its anticancer activity. Understanding the mechanism underlying the apoptosis-inducing effects is crucial. This study aimed to elucidate the apoptotic pathway and analyze the gas chromatography/mass spectrometry (GC/MS) profile of EEZO cells. The research commenced with the maceration of Zingiber officinale rhizomes using 75% ethanol to obtain EEZO. Apoptosis assays were conducted on both a negative control group and an EEZO-treated group of HeLa cells (cervical cancer cells). The apoptotic mechanism was evaluated using forward scattered light-side scattered light (FSC-SSC), fluorescein isothiocyanate (FTIC), and phycoerythrin (PE) flow cytometry. Apoptotic results were analyzed by comparing the control and EEZO samples, which revealed the number of viable cells, apoptotic cells, and cells in the sub-G1 phase. The major constituent of EEZO, which is expected to be a potent apoptosis inducer, was detected using GC/MS. The FSC-SSC results indicated a lower number of viable cells in the EEZO-exposed group than in the control group. FTIC results demonstrated that EEZO significantly increased apoptotic cell death, increasing from 68 to 1537 cells. PE flow cytometry revealed an elevated sub-G1 cell population, indicating the induction of apoptosis by EEZO. GC/MS analysis revealed five dominant components in EEZO, which had the potential to induce apoptosis: L-borneol, zingiberene, farnesol, beta-sesquiphellandrene, and alpha-curcumene. In conclusion, EEZO, with its dominant compound, zingeberene, induced apoptosis in HeLa cells, indicating anticancer potential

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