InterNano Nanomanufacturing Repository
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    1523 research outputs found

    Ligand-Decorated Nanogels: Fast One-Pot Synthesis and Cellular Targeting

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    Advanced Manufacturing Partnership: Where Does Nanomanufacturing Fit, and Where Should Investments Be Made?

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    The announcement of the Advanced Manufacturing Partnership (AMP) by the White House last June, followed by regional workshops to identify technology approaches for U.S. government investment to create high-quality manufacturing jobs and enhance the global competitiveness, demonstrates the Obama administration's commitment to revitalizing manufacturing in the US. The government/academic/industry AMP collaboration convened the workshops to exchange ideas between the AMP steering committee and stakeholders including entrepreneurs, manufacturing leaders, public officials, educators, students and the general public on how best to make it in America. Topics for discussion included technology development, education, workforce development, and shared infrastructure and facilities. The AMP steering committee heard from private sector leaders representing a wide range of manufacturing sectors and global corporations, as well as from federal and state policymakers. In evaluating the Advanced Manufacturing Partnership and the intended impact towards a sustainable and growing manufacturing base in the U.S., several aspects of the dialogue provide encouragement while quantifying the magnitude of the challenges faced. For example, workforce training at the high school and junior college levels includes new curricula and strategies, yet still faces the challenge of reinvigorating the perception of manufacturing careers for future generations. Many states have already established and begun execution of roadmaps and efforts in this area. Also included: Integrated Nanowire Logic Circuitry on Deformable Nonplanar Substrates, NanoBusiness Interview: Jason Hartlove, CEO, Nanosys, and Lead-Free Nanowire Piezoelectric Nanogenerator: Potential for Ubiquitous Powe

    Nanotechnology and Regulatory Science in FDA

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    Pixelligent

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    N3ASIC Based Nanowire Volatile RAM

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    Metalized DNA Electrodes for Improved Hole Collection Efficiency in Polymer Heterojunction Solar Cells

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    Deoxyribonucleic acids (DNA) provide exciting opportunities as templates in self assembled architectures and functionality in terms of optical and electronic properties. In this study, we investigate the effects of DNA and metalized DNA sequences in polymer fullerene bulk-heterojunction (BHJ) solar cells. These effects are characterized via optical, quantum efficiency and current-voltage measurements. We demonstrate that by placing on the hole collection side of the active layer, DNA and Pt-DNA sequences lead to an increase in the power conversion efficiency (POE) by %16 and %30, respectively. Then, we examine the metallization process with SEM and AFM images and optimized the metallic cluster formation on DNA by changing the duration of steps in the process. Furthermore, we studied the electrical charge characteristics of our DNA layer by using capacitance voltage (C-V) measurements to explain the increase in hole collection. The shift in the C-V measurements showed that spray coated DNA formed a negatively charged layer which can increase the hole collection on the cathode side

    Poly(lactic acid)-poly(ethylene oxide) Block Copolymers: New Directions in Self-Assembly and Biomedical Applications

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    In this review, we focus on recent developments in biomaterials of poly(lactic acid)-poly(ethylene oxide)-poly(lactic acid) (PLA-PEO-PLA) triblock copolymers. This system has been widely explored for a number of applications in controlled and sustained release of drugs and in tissue engineering devices. New insights into self-assembly of these materials have resulted in new PLA-PEOPLA solutions and gels with novel structural, mechanical, and drug release properties. Recent innovations include hydrogels with nanoscale crystalline domains, solutions and gels based on PLA stereocomplexes, and nanoparticle-copolymer assemblies. We first briefly review synthetic approaches to these materials. We then describe characterization of the solution properties, formation of micelles, drug release characteristics, and investigation of the sol-gel transition. The properties of PLA-PEO-PLA hydrogels are then discussed, including the effect of crystalline domains on the gel microstructure and efforts to tune the elastic modulus and degredation properties of gels through the addition of chemical crosslinks. In the second half of the review, we discuss the wide variety of biomedical applications currently being pursued for PLA-PEO-PLA triblock copolymer systems. Polymer-nanoparticle complexes have been investigated to facilitate the formation of metal nanoclusters used as biosensors, as well as to enhance the elastic modulus of hydrogels. Thin polymer films have also been investigated for use as tissue engineering scaffolds and as drug-eluding coatings for stents and other medical implants. Finally, we discuss future directions for biomedical applications of this system, including new strategies for improving the specificity and cell affinity of PLA-based biomaterials. [ABSTRACT FROM AUTHOR]Copyright of Current Medicinal Chemistry is the property of Bentham Science Publishers Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.

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