InterNano Nanomanufacturing Repository
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1523 research outputs found
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Nanoimprinting on Impregnated Fabric Substrates
No full textThe Carter and Crosby research groups have collaborated to develop new methods to overcome existing challenges in the use of nanoimprinting patterning on flexible substrates in a roll-to-roll configuration. One of the major challenges is the delamination of imprinted materials from flexible substrates, such as PET films.
To overcome delamination, we have recently proposed and demonstrated the use of woven substrates, rather than films, to allow mechanical interlocking to help in preventing unwanted delamination. In our process, we impregnate a woven fabric, with a curable formulation, which can subsequently be imprinted with a nanostructured pattern (top schematic). Our initial results (bottom images) are encouraging, and we are currently determining the material and spatial limits of this approach, as well as the mechanical properties of imprinted samples
Microfluidic Sensors for Resource-limited Areas
No full textAn ideal point-of-care device would incorporate the simplicity and reliability of a lateral flow assay with a microfluidic device. Our system consists of self-priming microfluidics with sealed conjugate pads of reagent delivery and an absorbent pad for additional fluid draw. Using poly (methyl methacrylate) (PMMA) as a substrate, we have developed a single-step surface modification method which allows strong capillary flow within a sealed microchannel. Conjugate pads within the device held trapped complex consisting of the magnetic beads and nucleic-acid-probe-conjugated horseradish peroxidase (HRP). Magnetic beads were released when sample entered the chamber and hybridized with the complex. The complex was immobilized over a magnet while a luminol co-reactant stream containing H2O2 was merged with the channel. A plate reader was able to quantify the chemiluminescence signal. This new format of biosensor will allow for a smaller and more sensitive biosensor, as well as commercial-scale manufacturing and low materials cost
From Technology Push to Market Pull: Commercializing Nanoscience Research via Startups and Spinouts
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Nanoparticle-Based Anticounterfeiting
No full textWe have developed an anti-counterfeiting strategy based on the ionization of ligands from gold nanoparticles. In practice, the particles were inkjet printed onto surfaces, and the "mass barcodes" arising from different ligands was read off using laser desorption mass spectrometry (LDI-MS). This method provides rapid and efficient authentication of materials, with applications in pharmaceuticals, currency, and other areas where counterfeiting is common
