InterNano Nanomanufacturing Repository
Not a member yet
1523 research outputs found
Sort by
Photo--Roll Lithography (PRL) for Continuous and Scalable Patterning with Application in Flexible Electronics
No full textMulti-stimuli responsive macromolecules and their assemblies
No full textIn this review, we outline examples that illustrate the design criteria for achieving macromolecular assemblies that incorporate a combination of two or more chemical, physical or biological stimuli-responsive components. Progress in both fundamental investigation into the phase transformations of these polymers in response to multiple stimuli and their utilization in a variety of practical applications are highlighted. Using these examples, we aim to explain the origin of employed mechanisms of stimuli responsiveness which may serve as a guideline to inspire future design of multi-stimuli responsive materials
Effectively Managing the Risks of Nanomaterials: Present Status and Future Challenges
No full textNanomaterials represent the building blocks of nanotechnology-enabled products and applications encompassing a broad range of substances and structures having features in the 1-100 nanometer range. Nanomaterials are of significant interest as they exhibit enhanced physical, chemical and electronic properties in comparison to their bulk counterparts. They can impact a range of applications including energy, electronics, agriculture, transportation, and healthcare, with the potential for pronounced societal and economic benefit. Yet the significant societal benefits offered by nanomaterials are not without possible drawbacks as the impact of exposure on human health and environment is presently unclear. While it is documented that significant and excessive exposure to certain types of nanomaterials can be hazardous to human health there are no data linking these exposure levels to realistic exposure conditions for responsible product manufacturing or product life-cycle.
Also included: Voltage Controlled Drug Release from Nanoparticles for Hybrid Smart Drug Delivery Systems, The Nano-economy: Time to Reap the Rewards, New Research Consortium to Develop Advanced Materials for Next-Generation Airbus Aircraf
Selective enrichment and sensitive detection of peptide and protein biomarkers in human serum using polymeric reverse micelles and MALDI-MS
No full textReverse-micelle forming amphiphilic homopolymers with carboxylic acid and quaternary amine substituents are used to selectively enrich biomarker peptides and protein fragments from human serum prior to matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis. After depletion of human serum albumin (HSA) and immunoglobulin G (IgG), low abundance peptide biomarkers can be selectively enriched and detected by MALDI-MS at clinically relevant concentrations by using the appropriate homopolymer(s) and extraction pH value(s). Three breast cancer peptide biomarkers, bradykinin, C4a, and ITIH4, were chosen to test this new approach, and detection limits of 0.5 ng mL-1, 0.08 ng mL-1, and 0.2 ng mL-1, respectively, were obtained. In addition, the amphiphilic homopolymers were used to detect prostate specific antigen (PSA) at concentrations as low as 0.5 ng mL-1 by targeting a surrogate peptide fragment of this protein biomarker. Selective enrichment and sensitive MS detection of low abundance peptide/protein biomarkers by these polymeric reverse micelles should be a sensitive and straightforward approach for biomarker screening in human serum
Interagency Public Access Coordination: A Report to Congress on the Coordination of Policies Related to the Dissemination and Long-Term Stewardship of the Results of Federally Funded Scientific Research
No full textAccelerating Progress for Advanced Manufacturing: Enabling Technologies, Barriers, Infrastructure, and Partnership Models for Roll-to-Roll Nanofabrication
No full textFlexible and printed electronics technologies have advanced to the stage where inexpensively printing high performance devices on continuous rolls of polymer-based substrates now promises to revolutionize advanced manufacturing. The recently published report from the NIST-NNN Workshop on Nanofabrication Technologies for Roll-to-Roll Processing, an Academic-Industry Workshop on Technologies for American Manufacturing Competitiveness, identifies and discusses progress and challenges for successful merging of nanofabrication technologies into advanced device manufacturing. The workshop further included discussions of general parameters for a multi-year technology roadmap to guide and accelerate progress in roll-to-roll (R2R) processing of nanoscale devices.
Also included: Chipping Away at Cancer, RTI International Launches Comprehensive Online Nanomaterial Registry, and Greener Nano 2012: Nanoinformatics Tools and Resources Worksho
Multiplexed Imaging of Nanoparticles in Tissues
No full textTo more fully understand the biodistributions and potential toxicity of nanoparticles (NPs) that are released into the environment, it is essential to monitor the spatial distributions of NPs in vivo. To this end CHM scientists have developed an approach based on laser desorption/ionization mass spectrometry (LDI-MS) to image NPs in tissues. Because MS is used as the readout for this imaging approach, multiple NPs can be imaged simultaneously, which facilitates the side-by-side comparison of different NP types. Results indicate that NPs can remain intact in animals and that biodistribution information can be directly obtained
Workshop on Nanotechnology Infrastructure: Final Report
No full textNanotechnology is generating entirely new scientific and technological opportunities that offer revolutionary solutions to major problems of society including energy, health, environment, climate, and economic development. The robust advancement of research and development for Nanotechnology within the United States will require the support of a state‐of‐the‐art physical infrastructure that is widely accessible. For the past decade, the National Nanotechnology Infrastructure Network (NNIN) has served as a major and enabling factor for extremely‐successful development. As the NNIN moves toward the end of its designated program term and as nanotechnology progresses toward the new Nanoscale systems, an important issue is: what capabilities should NSF generate and nurture in order to provide the important and critical needs for continued development of Nanotechnology? Accordingly NSF has supported a workshop of recognized national experts to evaluate the needs of, and appropriate future investments in, a national infrastructure for nanotechnology. The workshop was held in Arlington, VA on April 3‐4, 2012 with 22 participants representing a wide range of stakeholders. The participants examined the opportunities provided by a nanotechnology infrastructure as well as the needs of the scientific and technological communities for realization of these opportunities. On this basis, the workshop participants urge the formation of a new infrastructure network. As envisioned, the infrastructure network will build on the fundamental fabrication tools that have been developed by the electronics industry, including lithographic patterning. However the infrastructure will be distinguished from the current NNIN by incorporating the following major elements, to offer a much broadened scope and user‐base:
(1) Emphasis on utilization of the network nature of the program to provide value to the stakeholders far greater than individual components.
(2) A user‐base that is much broadened beyond electronics and electronic device fabrication to include less traditional communities such as environmental sciences, geosciences, and biosciences.
(3) Availability of new cutting edge fabrication capability to users who require it.
(4) Capabilities to create complex and three dimensional Nanoscale systems through heterogeneous integration.
(5) Capabilities to build Nanoscale systems across multiple dimensional scales through hierarchical design and fabrication.
(6) Major extension of capabilities for fabrication in soft matter including potentially biological interfaces.
(7) New generations of modeling and simulation along with the use of new design tools to maximize overall understanding and fabrication efficiency.
(8) Facilities capable of supporting the translation of discovery into prototypical elements suitable for evaluation of manufacturability and proof of business concept.
(9) Partnerships with industry, government, and other groups to provide specialized capabilities within the network when warranted. The network will also include linkages with other networks and federal infrastructure investments, such as facilities at NIST and DOE.
(10) Coherent unified program of education and outreach built upon the unique nature of the network and funded at a level commensurate with the goals and directions of the program.
(11) Commitment to support and champion environmental responsibility, health, and safety (EHS) by providing direct capabilities (characterization and fabrication/synthesis) as well as establishment of the benchmark for EHS within a university environment.
(12) Incorporation of understanding of societal and ethical implications (SEI) of nanotechnology.
This infrastructure network will cultivate support through strong partnerships and collaborations with other federal agencies with active interests in Nanoscale Science and Engineering as well as with industrial and governmental research facilities
Hybrid Low Resistance Ultracapacitor Electrodes Based on 1-Pyrenebutyric Acid Functionalized Centimeter-Scale Graphene Sheets
No full textUltracapacitors are promising candidates for alternative energy storage applications since they can store and deliver energy at relatively high rates. Here, we present hybrid nanocarbon ultracapacitor electrodes with a low equivalent series resistance (ESR) of 7 ohms. 1-pyrenebutyric acid treated large-area single layer graphene (SLG) sheets covered with shortened multi-walled carbon nanotubes (MWNTs) have been utilized as highly conductive and percolated networks of hybrid carbon nanomaterial composites or thin films as ultracapacitor electrodes. Uniform centimeter scale single layer graphene sheets were produced via low pressure chemical vapor deposition using copper foil substrates and then subsequently modified by 1-pyrenebutyric acid functionalization. Chemically shortened MWNTs ranging in length of 200 similar to 500 nm, were deposited by drop casting on 1-pyrenebutyric acid functionalized SLG films. SLG/MWNT nancomposite hybrid films of different thicknesses were obtained by controlling the density of MWNT suspension. Surface morphology and nanostructure of the hybrid nanocomposites indicated relatively dense and homogeneous weblike networks. Specific capacitance values of the hybrid electrodes were substantially increased by 200% compared to those ultracapacitors fabricated using buckypaper electrodes. Average values of specific capacitance and energy density obtained were 140.64 F/g and 21.54 Wh/kg respectively. SLG/MWNT nanocomposite electrodes are very promising for future ultracapacitor devices with their low ESR value that is 95% lower than that of buckypaper based ultracapacitors