InterNano Nanomanufacturing Repository
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Cost Effective Fabrication of Oriented Magnetic Thin Films With Large In-plane Uniaxial Anisotropy with Enhanced Energy Product by Nanoimprint Lithography
No full textTriennial Review of the National Nanotechnology Initiative Reiterates Need for Information Exchange, Effective Technology Transfer, and Commercialization
No full textThe National Research Council recently released its Triennial Review of the National Nanotechnology Initiative, a required assessment of the National Nanotechnology Initiative (NNI) by the 21st Century Nanotechnology Research and Development Act of 2003. This document makes recommendations to the Nanoscale Science, Engineering, and Technology (NSET) Subcommittee and to the National Nanotechnology Coordination Office (NNCO) “that will improve the NNI's value for basic and applied research and for development of applications in nanotechnology that will provide economic, societal, and national security benefits to the United States”. The assessment of federal research initiatives; NNI stakeholders; metrics, definitions of success, and data; NNI planning, management, and coordination frameworks; and technology transfer and commercialization are discussed
Computational Study of the Role of Elasticity in Liquid Transfer during a Simplified Gravure-like Processes
No full textSolution Processable High Dielectric Constant Nanocomposites Based on ZrO2 Nanoparticles for Flexible Organic Transistors
No full textPredicting the effects of surfactant coverage on drop size distributions of homogenized emulsions
No full textPopulation balance equation (PBE) models have been extensively used to predict drop size distributions of processed oil-in-water emulsions. Our previous work on high pressure homogenization demonstrated that both drop coalescence and breakage must be included to obtain satisfactory distribution predictions at high oil-to-surfactant ratios. While it was capable of predicting drop size distributions over a range of surfactant concentrations, this PBE model was not extensible to other surfactant types without re-estimation of adjustable model parameters. The objective of the present study was to develop a new PBE model that allows satisfactory prediction for emulsion systems with different surfactant types and concentrations given model parameters estimated from drop size distribution data collected for a single surfactant at a single concentration. This extended PBE model was developed from our previous model by adding a surfactant mass balance, including the effects of the free surfactant concentration on the interfacial tension and the surface coverage of drops and by modeling the coalescence frequency to be a function of the surfactant coverage. To demonstrate the approach, model parameters were obtained by nonlinear optimization using measured drop size distributions collected at 50 wt% oil and 1 wt% Pluronic F68 surfactant. These parameters were used to predict drop size distributions at 50 wt% oil and 0.5-2.0 wt% surfactant for Pluronic F68 and three other surfactants from the Pluronic family. We found that the extended PBE model generated substantially improved distribution predictions compared to our previous model, with the degree of improvement dependent of the surfactant used. These results represent an important step towards the use of PBE models for emulsified product design. Published by Elsevier Ltd
Designing electrospun nanofiber mats to promote wound healing - a review
No full textCurrent strategies to treat chronic wounds offer limited relief to the 7.75 million patients who suffer from burns or chronic skin ulcers. Thus, as long as chronic wounds remain a global healthcare problem, the development of alternate treatments remain desperately needed. This review explores the recent strategies employed to tailor electrospun nanofiber mats towards accelerating the wound healing process. Porous nanofiber mats readily produced by the electrospinning process offer a promising solution to the management of wounds. The matrix chemistry, surface functionality, and mat degradation rate all can be fine-tuned to govern the interactions that occur at the materials-biology interface. In this review, first we briefly discuss the wound healing process and then highlight recent advances in drug release, biologics encapsulation, and antibacterial activity that have been demonstrated via electrospinning. While this versatile biomaterial has shown much progress, commercializing nanofiber mats that fully address the needs of an individual patient remains an ambitious challenge
Multiplexed Imaging of Nanoparticles in Tissues Using Laser Desorption/Ionization Mass Spectrometry
No full textImaging of nanomaterials in biological tissues provides vital information for the development of nanotherapeutics and diagnostics. Multiplexed imaging of different nanoparticles (NPs) greatly reduces costs, the need to use multiple animals, and increases the biodistribution information that can enhance diagnostic applications and accelerate the screening of potential therapeutics. Various approaches have been developed for imaging NPs; however, the readout of existing imaging techniques relies on specific properties of the core material or surface ligands, and these techniques are limited because of the relatively small number of NPs that can be simultaneously measured in a single experiment. Here, we demonstrate the use of laser desorption/ionization mass spectrometry (LDI-MS) in an imaging format to investigate surface chemistry dictated intraorgan distribution of NPs. This new LDI-MS imaging method enables multiplexed imaging of NPs with potentially unlimited readouts and without additional labeling of the NPs. It provides the capability to detect and image attomole levels of NPs with almost no interferences from biomolecules. Using this new imaging approach, we find that the intraorgan distributions of same-sized NPs are directly linked to their surface chemistry
Hydrophobization of Inorganic Oxide Surfaces Using Dimethylsilanediol
No full textDimethylsilanediol is a stable crystalline solid that was described in 1953. As the monomer of an important class of commercial products (poly(dimethylsiloxanes)-silicones, PDMS) and as a simple molecule in its own right (the silicon analog of acetone hydrate), it has been neglected by several fields of fundamental and applied research including the hydrophobization of inorganic oxide surfaces. We report that dimethylsilanediol is a useful reagent for the surface modification (hydrophobization) of oxidized silicon and other oxidized metal surfaces and compare the wetting properties of modified solids with those of conventionally modified surfaces. That water is the only byproduct of this modification reaction suggests that this and likely other silanediols are useful surface-modification agents, particularly when substrate corrosion or the competitive adsorption of byproducts is an issue. We note that dimethylsilanediol is volatile with a significant vapor pressure at room temperature. Vapor phase surface modifications are also reported