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Archeologia urbana nel quartiere ebraico medievale di Alghero. Lo scavo di piazza Santa Croce: sequenza stratigrafica e materiali ceramici.
Get PDFThis thesis is based on the results from the examination of ceramics and stratigraphic data obtained through the archaeological dig in Piazza Santa Croce, Alghero, between 1997 and 1998. The stratigraphic sequence was particularly clear and it led to a detailed analysis of the ceramic materials. These items clarified the phases of the Ligurian foundation of the city (mid 13th century) and the Crown of Aragon conquest in the mid 14th century.
The excavation exposed a building from the Jewish quarter of the city, abandoned in the late 15th century due to the Expulsion Edict issued by Ferdinand II the Catholic. This information was gathered from a series of stratifications which can be dated around the early and second half of the 16th century.
The structure was then finally demolished and buried by large land repositories rich in ceramic artifacts dating back to the late sixteenth and seventeenth centuries, from the analysis of which it was possible to obtain numerous commercial information. Santa Croce Church was built at this level and its stages of use have been identified around the 16th and 19th centuries. During this period there were frequent burials under the floor of the church and the exterior churchyard was also partially covered by dirt. The church was demolished at the beginning of the 20th century and the Piazza was created in it's contemporary form
Dose-dependent effect of Resveratrol on human endothelial cell functions
Get PDFPurpose - Resveratrol consumption has been shown to exhibit cardiovascular-preventive and anticancer activities in preclinical studies. The mechanism of Resveratrol effect on human umbilical vein endothelial cell proliferation and apoptosis were not clearly understood. This study was undertaken to study on the dose-dependent effect of Resveratrol on HUVEC function and identify the potential signals involved in this pathway.
Experimental Design and Results - HUVECs were used as described in this study. Treatment of HUVECs with the concentrations of 1 and 100 µM RES showed that low concentrations increase cell growth, and decrease intracellular ROS levels while high concentrations cause the opposite effect significantly. The result of DNA fragmentation experiments may indicate cell death by apoptosis in HUVECs related to the expression of Bax and the decrease of the expression of Bcl-2. Using RES 50 μM, is consistent with the significant increase in DNA fragmentation, a typical marker of apoptosis. And at this concentration, RES makes endothelial cell cycle arrest by reducing Cyclin D1 and ODC, c-myc expression. Resveratrol dose-dependently modulates PKC activity on HUVEC proliferation and apoptosis.
Conclusion - Our data indicated that the RES effect on HUVECs is biphasic. PKC appears to be the potential mediator of the observed Resveratrol effect on HUVEC functions (proliferation, apoptosis), hypothesized this linked to the intracellular ROS levels
Indagine sulle modificazioni post-traduzionali della tubulina e caratterizzazione funzionale dell’ovocita di ovino adulto e prepubere maturato in vitro e vitrificato
Get PDFStudy on tubulin post-translational modifications and functional characterization of ovine oocytes in vitro matured and vitrified.
In the present thesis morphological, ultrastructural and metabolic conditions of adult and prepubertal IVM and vitrified ovine oocytes were explored, In IVM oocytes, by immunofluorescence, several tubulin post-translational modifications (total, tyrosinated, acetylated and detyrosinated, polyglutamylated and Δ2 tubulin) were investigated for the first time. Results revealed a well detectable signal only for total, tyrosinated and acetylated α-tubulin in both sheep and lamb oocytes. As regard tyrosinated and acetylated tubulin, there were no significant differences in their expression in sheep, while in lamb the acetylated level was predominant in comparison with tyrosinated. The different microtubular pattern between adult and prepubertal oocytes, suggest a possible role of microtubules in the acquisition of oocytes competence.
In vitrified adult and prepubertal oocyte we assessed the ability to recover from vitrification-induced damages after warming. Tyrosinated and acetylated α-tubulin levels, mithocondrial pattern, ROS levels and developmental competence were investigated. Results revealed that vitrified/warmed sheep oocytes need an extra time to restore damage due the cryopreservation procedures. On the contrary the vitrified/warmed lamb oocytes showed structural damages in spindle and chromatin, with high rates of parthenogenetic activations, displaying a lack of molecular tools useful for both cytoskeleton reorganization and developmental competence
Il Lessico dell'oggettistica alimentare nel Medioevo latino
No full textLa tesi di dottorato ha per oggetto il lessico degli utensili e del vasellame per la tavola e per la mensa nel Medioevo latino ed è composta da quattro capitoli. Dopo un quadro introduttivo dell'alimentazione e della cucina nel Medioevo, è descritto il metodo di lavoro seguito nella costruzione del repertorio lessicale ed è proposto un bilancio conclusivo relativo al repertorio. Il quarto capitolo ospita il repertorio
La Condizione della donna nella Sardegna giudicale alla luce dei condaghi
Get PDFThis study analyzes the status and role of women in medieval Sardinia between XI and XIII century. Women have been considered in different contexts: within the family and outside the domestic sphere, and about their legal rights and economic conditions. These topics have been studied in relation to different social groups, in territorial and diachronic way, highlighting their features in each of the Sardinian kingdoms (giudicati). The main historical sources are the condaghes, collections of administrative documents of Sardinian monasteries and other ecclesiastical or secular institutions. Every record (scheda) in which women appeared (donation, inheritance, purchase, transaction and litigation) has been classified and analyzed to provide a profile of queens and princesses (donnikellas), to describe the characteristics of free aristocratic and not‑aristocratic women, and to understand the conditions of female servants living under the authority of secular or ecclesiastical owners
Six new <i>Phytophthora</i> species from ITS Clade 7a including two sexually functional heterothallic hybrid species detected in natural ecosystems in Taiwan
No full textDuring a survey of Phytophthora diversity in natural ecosystems in Taiwan six new species were detected. Multigene phylogeny based on the nuclear ITS, ß-tubulin and HSP90 and the mitochondrial cox1 and NADH1 gene sequences demonstrated that they belong to ITS Clade 7a with P. europaea, P. uniformis, P. rubi and P. cambivora being their closest relatives. All six new species differed from each other and from related species by a unique combination of morphological characters, the breeding system, cardinal temperatures and growth rates. Four homothallic species, P. attenuate, P. flexuosa, P. formosa and P. intricata, were isolated from rhizosphere soil of healthy forests of Fagus hayatae, Quercus glandulifera, Q. tarokoensis, Castanopsis carlesii, Chamaecyparis formosensis and Araucaria cunninghamii. Two heterothallic species, P. xheterohybrida and P. xincrassata, were exclusively detected in three forest streams. All P. xincrassata isolates belonged to the A2 mating type while isolates of P. xheterohybrida represented both mating types with oospore abortion rates according to Mendelian ratios (4–33 %). Multiple heterozygous positions in their ITS, ß-tubulin and HSP90 gene sequences indicate that P. xheterohybrida, P. xincrassata and P. cambivora are interspecific hybrids. Consequently, P. cambivora is re-described as P. xcambivora without nomenclatural act. Pathogenicity trials on seedlings of Castanea sativa, Fagus sylvatica and Q. suber indicate that all six new species might pose a potential threat to European forests
Tools for the numerical solution of inverse problems in structural mechanics: review and research perspectives
No full textIn this work, the author gives a review of the state of the art on the computational strategies developed for the analysis of inverse problems. Starting from the definition of the inverse problem, and focusing the intrinsic difficulties in their solution, various computational tools developed for their solution are presented and discussed. This allows an aware choice of the most effective strategies with respect to the problem to be dealt with. Successively, some selected inverse problems are briefly sketched and their numerical solution is thoroughly discussed. This allows to enlighten the main problems to overcome and the attainable accuracy. Finally, new and challenging inverse problems are addressed, discussing thoroughly some current and classical results, in order to outline future perspectives
International congress on cork oak trees and woodlands: conservation, management, products and challenges for the future: book of abstracts
No full textIl congresso affronta le principali tematiche della filiera, dalla biodiversità alla pianificazione forestale, dall’economia alla trasformazione industriale del sughero, con l'intenzione di fare il punto della situazione e svolgere un ruolo di raccordo sia tra ricercatori delle due sponde del Mediterraneo sia tra il mondo della ricerca e quello dell’industria
Local landscape dynamics in a traditional cork-oak agro-forest system (Sardinia)
No full textThe Alta Gallura region contributed to the development of Italian cork industry that since the nineteenth century has driven the improvement of a multi-functional model based on the breeding of beef cattle into the cork oak forests.
The study case is a cork-oak agro-forest farm extended to 212 hectares, with a quantity of livestock close to 0.1 LU ha-1. It were collected data from the farm registry (business records of the last 70 years) and by photo-interpretation of images related to 1955 (GAI), 1977 (CGR), 2006 (Terra Italy) and 2013 (AGEA)
La Ricerca scientifica in una manifestazione tradizionale a cavallo: il caso-studio della Sartiglia di Oristano
Get PDFThe Sartiglia is a traditional horse joust held in Oristano, Italy, since the 16th century during Carnival celebrations. This kind of events are often criticized because of
possible concerns linked to health and welfare of animals. The aim of this thesis is to present two scientific papers, which can potentially provide useful information about
possible critical points and remedial strategies. The first evaluates the physiological response and the health status of horses in response to the different stages of the event.
Blood tests evidence that horses are in optimal health, also before the start of the tournament, and changes of blood parameters are quickly recovered to baseline values.
The second paper reports an investigation about the validation of reference intervals for thermographic values of limbs’ regions. A large distribution of temperatures is
recorded on clinically healthy horses. This can represent a problem for the possible prediction of subclinical disease. However, as the use of thermography in the horse is
still sporadic the survey may be useful as a benchmark study. In addition, we should not underestimate the involvement and cooperation of various institutions and the
possible adaptation of scientific protocols to the strict and ancient stages of a traditional event. The interpretation of the results can lead to a direct benefit linked to animal welfare and the organization of the Sartiglia