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A Short-Cycle Framework Approach to Integrating Psychometric Feedback and Data Analytics to Rapid Cyber Defense
No full textFollowing earlier research in demonstrating the significance of behavioral analysis in cyber defense, the authors developed a framework to incorporating multi-disciplinary datasets along a common timeline to increase incident response feedback for coaching. Currently this framework is being introduced in the state of Colorado, USA as a part of a joint government, industry and academic partnership. Upon project initiation, the feedback cycle had been a minimum of several months from observation to feedback. Presented here is a new framework that can shorten the cycle of psychometric feedback to multiple times in one training day. This Short-Cycle Framework, gathering psychometric and cyber data to provide direct feedback to cyber defense team leaders, was conceived when Regis University’s psychometric evaluators observed a real multi-agency cyber defense response. The authors realized the psychometric data can be used in live cyber defense incidents alongside things like network firewall traffic analysis as the cyber defenders provide relief for organizations under active cyber attack. This work presents the context in which the framework was developed, the characteristics of the framework, and suggestions for further research. The framework implements a specific set of short-term state indicators based on well-known personality trait and state models. The coaching cycle was scripted to shorten the delay between observation and feedback so that it can be more useful in both training and live incident response
A Journey from Patient Care to Jesuit Higher Education: How a Small Group of Healthcare Professionals Navigated the Transition into Academia
No full textIn the fall of 2015, four experienced healthcare clinicians met as strangers at an orientation at a Jesuit institution, Regis University. From the professions of occupational therapy, pharmacy, and physical therapy, we felt comfortable with our clinical practice in patient-centered care and our healthcare work environments. Eager to share our knowledge with our students, we needed guidance to perform the key roles of an educator such as creating a syllabus, writing test items, and advising students. As we began our careers in academia, we felt disoriented and chaotic. We directly sought structure to bridge knowledge gaps, establish a sense of community, and identify essential resources necessary for success in academia. We desired to explore our own interpretation of the Jesuit values before trying to infuse them into our teaching. Through the creation of a small professional learning group that combined emotional support and professional growth, we established a structured approach to learning the roles of a professor and found our identities as academicians. We aim to share our journey and provide recommendations for other healthcare clinicians who are inexperienced with academia in the hopes of easing the transition from clinician to educator at a Jesuit University
Truth, Knowledge & Storytelling: Postcolonial Aspects of Epistemological Problems in the Works of Gabriel García Márquez
Get PDFThe purpose of this thesis is to explore epistemological problems in various works of Gabriel García Márquez. Understanding and questioning who tells the story and who has the right to tell the story is an important question that guides this project. Through understanding important historical events of Colombia like the Banana Massacre and key events within One Hundred Years of Solitude different epistemological issues become apparent.
The question of representation and who tells the story matters because it greatly affects the story that is told. Countries and people who have been stripped or denied a voice often face challenges in gaining one or never do. This means that they are then not represented in any way. García Márquez reclaims the history of Colombia by presenting a story that had previously not been shared and therefore helps to give representation back to his own country
Encountering Eastern Catholicism
Get PDFThe author reflects on their interfaith education in the Religious Studies department at Regis University and their lifelong experience as an American Roman Catholic
Methods to Compare Adverse Events in Twitter to FAERS, Drug Information Databases, and Systematic Reviews: Proof of Concept with Adalimumab
No full textIntroduction: Adverse drug reactions (ADRs) are associated with significant health-related and financial burden, and multiple sources are currently utilized to actively discover them. Social media has been proposed as a potential resource for monitoring ADRs, but drug-specific analytical studies comparing social media with other sources are scarce. Objectives: Our objective was to develop methods to compare ADRs mentioned in social media with those in traditional sources: the US FDA Adverse Event Reporting System (FAERS), drug information databases (DIDs), and systematic reviews. Methods: A total of 10,188 tweets mentioning adalimumab collected between June 2014 and August 2016 were included. ADRs in the corpus were extracted semi-automatically and manually mapped to standardized concepts in the Unified Medical Language System. ADRs were grouped into 16 biologic categories for comparisons. Frequencies, relative frequencies, disproportionality analyses, and rank ordering were used as metrics. Results: There was moderate agreement between ADRs in social media and traditional sources. “Local and injection site reactions” was the top ADR in Twitter, DIDs, and systematic reviews by frequency, ranked frequency, and index ranking. The next highest ADR in Twitter—fatigue—ranked fifth and seventh in FAERS and DIDs. Conclusion: Social media posts often express mild and symptomatic ADRs, but rates are measured differently in scientific sources. ADRs in FAERS are reported as absolute numbers, in DIDs as percentages, and in systematic reviews as percentages, risk ratios, or other metrics, which makes comparisons challenging; however, overlap is substantial. Social media analysis facilitates open-ended investigation of patient perspectives and may reveal concepts (e.g. anxiety) not available in traditional sources
Effectiveness of dry needling of rectus abdominis trigger points for the treatment of primary dysmenorrhoea: A randomised parallel-group trial
No full textObjective To compare the effectiveness of trigger point dry needling (TrP-DN) versus placebo needling, relative to an untreated control group, on pain and quality of life in primary dysmenorrhoea. Methods In this randomised, single blind, parallel-group trial, 56 females with primary dysmenorrhoea were randomly allocated to TrP-DN (n=19), placebo needling (n=18) or no treatment (n=19). Patients in both groups were asked to undertake a stretching exercise of the rectus abdominis daily. The needling group received a single session of TrP-DN to trigger points (TrPs) in the rectus abdominis, and the placebo group received placebo needling. The primary outcome was pain intensity (visual analogue scale). Secondary outcomes were quality of life, use of non-steroidal anti-inflammatory drugs, the number of days with pain, and self-perceived improvement, measured using a Global Rate of Change. Outcomes were assessed at baseline, and 1 and 2 months after the treatment. Results Females receiving TrP-DN exhibited greater decreases (P\u3c0.001) in pain than those receiving placebo (1 month: Δ-19.8 mm, 25.9 to -13.7; 2 months: Δ-26.0 mm, -33.1 to -18.9) or assigned to the untreated control group (1 month: Δ-26.0mm, -32.5 to -19.5; 2 months: Δ-20.1 mm, -26.4 to -13.8). Females in the TrP-DN group also exhibited a greater decrease in the amount of medications (P\u3c0.001). No differences in the number of days with pain or quality of life were found (all P\u3e0.1). Conclusions This trial suggests that a single session of TrP-DN of the rectus abdominis combined with stretching was more effective than placebo needling and stretching alone at reducing pain and the amount of medication used in primary dysmenorrhoea. Trial registration number ACTRN12616000170426
Negation, Structure, Transformation: Alain Badiou and the New Metaphysics
No full textIn this article, I discuss Alain Badiou\u27s 2008 address titled The Three Negations. Though the text was originally presented in a symposium concerning the relationship of law to Badiou\u27s theory of the event, I discuss the way this brief address offers an introduction to the broad sweep of Badiou\u27s metaphysics, outlining his accounts of being, appearing, and transformation. To do so, Badiou calls on the resources of three paradigms of negation: from classical Aristotelian logic, from Brouwer\u27s intuitionist logic, and in paraconsistent logics developed by DaCosta. I explain Badiou\u27s use of negation in the three primary areas of his metaphysics, as well as to diagnose the degrees of transformation that may have occurred in a situation. My analysis of Badiou\u27s use of negation in this text is aided by examples from his broader ontological oeuvre. I also explain the underlying requirement in Badiou\u27s work that formal considerations - mathematical or logical - get their sense by being tethered to readily-identifiable political, aesthetic, scientific, or interpersonal concerns. I conclude by addressing the foundation Badiou\u27s work establishes for pursuing a new metaphysics, and by discussing certain of the liabilities that remain in the wake of his account
Bacterial vaginosis: A review
No full textBacterial vaginosis (BV), a common infection in women, occurs when the balance of normal vaginal flora is disrupted by the replacement of Lactobacillus species (spp.) in the vagina with high concentrations of anaerobic bacteria. Guidelines for treating sexually transmitted diseases, which were updated by the CDC in 2015, recommend oral metronidazole, intravaginal metronidazole gel, or intravaginal clindamycin cream for the treatment of BV. Alternative agents include oral tinidazole, oral clindamycin, and clindamycin ovules. Following publication of the CDC guidelines, secnidazole—a nitroimidazole agent with a long half-life—was approved for treatment of BV. Pharmacists are in a key position to actively work with healthcare providers to select the most appropriate treatment regimen, monitor for adverse effects, and provide counseling and recommendations for preventive measures in patients with BV
Change in symptom clusters in head and neck cancer patients undergoing postoperative radiotherapy: A longitudinal study
No full textPurpose: Research on symptom clusters is a newly emerging field in oncology; however, little evidence regarding symptom clusters in head and neck cancer (HNC) is currently available. To clarify this under-researched area, we investigated symptom clusters among patients with HNC treated with surgery and postoperative radiotherapy. We also examined the pattern of symptom clusters throughout the treatment course. Method: A convenience sample of 100 patients with HNC was recruited in the Ear, Nose, and Throat unit of a medical center in Taiwan. Before undergoing postoperative radiotherapy, patients were asked to complete the MD Anderson Symptom Inventory and a demographic sheet. Patients completed the same inventory questionnaire at week 1, 2, 3, 4, 5, and 6 of radiotherapy. Result: Two symptom clusters were observed, and they were stable throughout the course of radiotherapy. Cluster 1, the HNC-specific cluster, comprised the symptoms of pain, dry mouth, lack of appetite, sleep disturbance, fatigue, drowsiness, distress, and sadness. Cluster 2, the gastrointestinal cluster, included nausea, vomiting, numbness, shortness of breath, and difficulty remembering. Conclusion: This study advanced our knowledge of symptom clusters in patients with HNC. The results are expected to contribute to the development of appropriate assessment and nursing interventions targeting multiple symptoms that may coexist in postoperative radiotherapy