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    Characterization and expression analysis of KIT and MITF-M genes in llamas and their relation to white coat color

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    The llama (Lama glama) is a fiber-producing species that presents a wide range of coat colors, among which white is one of the most important for the textile industry. However, there is little information about the molecular mechanisms that control the white phenotype in this species. In domestic mammals, a white coat is usually produced by mutations in the KIT proto-oncogene receptor tyrosine kinase (KIT) and microphthalmia-associated transcription factor (MITF) genes. In this work we have sequenced and described the coding regions of KIT and MITF-M, the melanocyte-specific isoform, and the two transcriptional variants MITF-M( ) and MITF-M(+). Moreover, we studied the expression of these genes in the skin of white and colored llamas. Although no variants were revealed to be associated with white coat color, significant differences between phenotypes were observed in the expression levels of KIT and MITF-M. Interestingly, white llamas expressed less MITF-M(+) than did colored ones, which is consistent with a consequent reduction in the synthesis of melanin. Even though our results indicate that downregulation of KIT and MITF-M expression is involved in white phenotype production in llamas, the causative gene of white coat color remains unknown

    Introducción al Dossier: Las agendas del diseño en el siglo XXI desde la perspectiva de la sustentabilidad social y ambiental en Argentina y Latinoamérica

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    El presente Dossier temático de la revista Cartografías del Sur busca promover el debate sobre los Objetivos de Desarrollo Sustentable 2030 y el impacto en las agendas del Diseño

    Effect of Abscisic Acid (ABA) Combined with Two Different Beekeeping Nutritional Strategies to Confront Overwintering

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    In temperate climates, beekeeping operations suffer colony losses and colony depopulation of Apis mellifera during overwintering, which are associated with biotic and abiotic stressors that impact bees’ health. In this work, we evaluate the impacts of abscisic acid (ABA) dietary supplementation on honey bee colonies kept in Langstroth hives. The effects of ABA were evaluated in combination with two different beekeeping nutritional strategies to confront overwintering: “honey management” and “syrup management”. Specifically, we evaluated strength parameters of honey bee colonies (adult bee and brood population) and the population dynamics of Nosema (prevalence and intensity) associated with both nutritional systems and ABA supplementation during the whole study (late autumn-winter-early spring). The entire experiment was designed and performed with a local group of beekeepers, “Azahares del sudeste”, who showed interest in answering problems associated with the management of honey bee colonies during the winter. The results indicated that the ABA supplementation had positive effects on the population dynamics of the A. mellifera colonies during overwintering and on the nosemosis at colony level (prevalence) in both nutritional strategies evaluated

    Improving resource productivity at a crop sequence level

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    The challenge to increase agricultural production with a minimum environmental impact requires to reach themaximum effiency in the capture and use of resources such as photosynthetically active radiation (PAR), water,and nitrogen (N). Such requisites are encompassed in the ecological intensifiation (EI) concept. The aims of this work were to evaluate at a crop sequence level: i) crops yields, ii) water and radiation productivity and itscomponents, i.e. resource capture and resource use effiency, and iii) partial factor productivity of applied N(PFPN), partial nutrient balance for N (PNB), N uptake and N utilization effiency of a two-year, three-cropsequence (wheat [Triticum aestivum L.]/soybean [Glycine max (L.) Merr.] double crop – maize [Zea mays L.])carried-out under EI principles in comparison with the same crop sequence under current farmer practices (FP) intwo contrasting locations of the Argentinean Pampas, i.e. Paraná (-31°50′; -60°31′) at the northern Pampas andBalcarce (-37°45′, -58°18′) at the southern Pampas. Experiments were carried-out during four consecutive years,covering two complete cycles of the crop sequence. For the accumulated grain production of the crop sequence, EI management outyielded FP from 13 to 42%, depending on environmental conditions. Maize yield accounted formost of the variation (41–64%) of the accumulated grain yield of crop sequence, whether in EI as in FP. Averagegrain yield diffrences between EI and FP treatments were 274 g m−2 for maize, 69 g m−2 for wheat and -2 g m−2for soybean. Water and radiation productivities of the sequence were higher in EI than in FP (26% for water and17% for radiation; P < 0.0001), mainly because of increases in resource use effiencies. EI reduced partial factorproductivity of applied N, but improved partial nutrient balance for N as compared with FP. These reductions inpartial factor productivity of applied N were less than proportional than the increases in N rate. Moreover, in spiteof the higher N rate in EI respect to FP, N utilization effiency (NutE), i.e. grain per unit N uptake, was higher across all situations in EI. Our results showed that the challenge to obtain high grain yields by increasing N rate in amedium-input system could be achieved even with an increase in NutE. Grain yields improvements, and increasesin radiation and water productivity were reached by applying a set of agronomic practices that included improvedgenetics, crop and fertilizer N management englobed under EI concept

    Analysis and Correction of Digital Elevation Models for Plain Areas

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    Water movement modeling in plain areas requires digital elevation models (DEMs) adequately representing the morphological and geomorphological land patterns including the presence of civil structures that could affect water flow patterns. This has a direct effect on water accumulation and water flow direction. The objectives of this work were to analyze, compare and improve DEMs so surface water movement in plain areas could be predicted. In order to do that, we evaluated the accuracy of a digital elevation data set consisting in 4064 points measured with a differential global positioning system (GPS) in a plain area of central Buenos Aires province. Three DEMs were analyzed: (1) the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), (2) the Shuttle Radar Topography Mission (SRTM) and (3) the Advanced Land Observing Satellite with the Phased Array Type L-Band Synthetic Aperture Radar (ALOS PALSAR). Several topographic attributes (i.e., height, surface area, land slope, delimitation of geomorphological units, civil structures, basin boundaries and streams network) and different interpolation methods were analyzed. The results showed that both the SRTM and the ALOS PALSAR DEMs had a ± 4.4 m root mean square error (RMSE) in contrast to the ASTER DEM which had a ± 9 m RMSE. Our analysis proved that the best DEM representing the study area is the SRTM. The most suitable interpolation methods applied to the SRTM were the inverse distance weighting and the ANUDEM, whereas the spline method displayed the lowest vertical accuracy. With the proposed method we obtained a DEM for the study area with a ± 3.2 m RMSE, a 33% error reduction compared to the raw DE

    SEDICI: Servicio de Difusión de la creación intelectual Universidad Nacional de La Plata

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    Esta presentación está dedicada a difundir el SEDICI. En la misma se muestran los contenidos del repositorio y particularmente las colecciones y recursos destacados de la Facultad de Ciencias Económicas que se encuentran en el repositorio. Se expone cómo localizar diferentes recursos en el SEDICI y especialmente aquéllos de la FCE. Se muestra el circuito de autoarchivo explicando un caso concreto

    Informe científico de investigador: Blasi, Adriana Mónica (2017-2019)

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    En el marco de mi disciplina de especialización, Geología del Cuaternario, Sedimentología y Geoarqueología, las investigaciones realizadas aportan al conocimiento estratigráfico, paleoambiental y paloclimático de la depositación ocurrida en la Pampa Bonaerense durante el lapso Pleistoceno tardío-Holoceno. Los suelos de la región se desarrollan, en su mayoría, a expensas de éstos registros sedimentarios, como así también las ocupaciones humanas más tempranas del territorio. Los estudios comprenden: 1) el conocimiento sedimentológico y estratigráfico del Pleistoceno tardío-Holoceno en las cuencas fluviales y los cambios ambientales y climáticos del área en la cuenca Salto-Arrecifes ; 2) los estudios Geoarqueológicos, realizados con un equipo multidisciplinario, dirigidos por el Dr. G. Politis y Dra. Castiñeira, que abarcan los estudios de formación de sitio-ocupaciones humanas en la margen oriental del río Uruguay, del Delta Superior del Paraná, del sitio Arroyo Seco (partido de Tres Arroyos) y Monte Hermoso 1 y La Olla en la costa Atlántica Bonaerense y 3) los trabajos en una nueva línea de investigación que persiguen la obtención de nuevos conocimientos sobre el desarrollo de matas microbianas en ambientes peritidales fósiles y de las estructuras sedimentarias bio-incucidas asociadas, bases para futuras líneas de investigación en remediación de aguas contaminadas. 4) También se encara la generación de conocimiento sobre la geologia superficial del partido de Adolfo Alsina, con vistas a confeccionar el mapa geomorfológico-ambiental y el estudio de la naturaleza mineralógica y química de los fangos mineromedicinales de la Laguna Epecuén

    Acta nº 1494

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    Incluye los siguientes anexos: - Anexo 3.1.1. Bases Concurso de Becas Doctorales BDOC20 - Anexo 3.5.1. Convocatoria a Subsidios para Asistencia a Reuniones Científicas y Tecnológicas ARCT19-20 - Anexo 3.5.2. Convocatoria a Subsidios para Organización de Reuniones Científicas y Tecnológicas ORCT19-20 - Anexo 3.5.3. Convocatoria a Subsidios para Publicaciones Científicas y Tecnológicas PDCT19-20 - Anexo 4.1. Concurso Público para la selección de Director Regular IMBICE, CIDEPINT, CIOP. Solicitada - Anexo 4.2. Informe de avance del Proyecto Institucional Nueva cadena de valor para el glicerol: Producción de Bio-glicoles , por la Dra. Nora N. Nichio - Anexo 4.3. Programa de Crédito Fiscal 201

    Acta nº 1493 Extraordinaria

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    Incluye el siguiente anexo: - Anexo 2.1 Aprobación del Reglamento Interno del Instituto de Investigación sobre Conocimiento y Políticas Públicas (CPP

    Zirconia-Supported Silver Nanoparticles for the Catalytic Combustion of Pollutants Originating from Mobile Sources

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    This work presents the physicochemical characterization and activity of zirconia-supported silver catalysts for the oxidation of pollutants present in diesel engine exhaust (propane, propene, naphthalene and soot). A series of silver-supported catalysts AgxZ (x = 1, 5 and 10 wt.%, Z = zirconia) were prepared, which were studied by various characterization techniques. The results show that silver is mainly found under the form of small metal nanoparticles (<10 nm) dispersed over the support. The metallic phase coexists with the AgOx oxidic phases. Silver is introduced onto the zirconia, generating Ag–ZrO2 catalysts with high activity for the oxidation of propene and naphthalene. These catalysts also show some activity for soot combustion. Silver species can contribute with zirconia in the catalytic redox cycle, through a synergistic effect, providing sites that facilitate the migration and availability of oxygen, which is favored by the presence of structural defects. This is a novel application of the AgOx–Ag/ZrO2 system in the combustion reaction of propene and naphthalene. The results are highly promising, given that the T50 values found for both model molecules are quite low

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