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Knowledge Measure for Interval-Valued Neutrosophic for Quality Evaluation of Integrating Excellent Traditional Chinese Culture into Ideological and Political Teaching
No full textQ-Neutrosophic Type-2 Soft Set (T2-QNSS) for Tourism Development Potential Analysis of Intangible Cultural Heritage Resources from the Perspective of Cultural and Tourism Integrations
No full textA Neutrosophic Topological Framework for AIGC-Driven Digital Media Content Automated Generation Technology
No full textFermatean Neutrosophic Hypersoft Set and Its Application to Impact Analysis of Green Power Trading in Uncertain Electricity Markets
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A Neutrosophic Approach for Evaluating the Multimedia-Aided College Piano Instruction Evaluation Techniques: Dombi-Based Heronian Mean Operators
No full textMicroneedle-based LC-MS/MS profiling of dermal interstitial fluid reveals early lipid dysregulation contributing to painful neuropathy in prediabetic and type 2 diabetic rats.
No full textPainful diabetic neuropathy (PDN), a complication of type 1 and type 2 diabetes, also occurs in obesity and prediabetes, with dyslipidemia as a modifiable risk factor. The distal-to-proximal neuropathy pattern and length-dependent intraepidermal nerve fiber loss suggest peripheral contributions. We hypothesized that elevated neurotoxic lipid intermediates—diacylglycerols (DAG), free fatty acids (FFA), and acylcarnitines (CARs)—in the dermal interstitial fluid (ISF) drive metabolism-associated hyperalgesia in prediabetic and diabetic rats. Using a microneedle array (MIA) with LC-MS/MS, we profiled ISF and serum lipids from high-fat diet (HFD) and HFD + streptozotocin (STZ) rat models alongside Hargreaves testing. ISF lipid changes appeared earlier (weeks 1–4) than serum dyslipidemia (after 10 weeks) and correlated strongly with serum lipids. Elevated ISF triacylglycerols, DAG, CARs, sphingomyelins, phosphatidylcholine, lysophosphatidylcholine, and lysophosphatidylethanolamine negatively correlated with paw withdrawal latency (r = –0.92, P \u3c 0.05). Dermal interstitial dyslipidemia precedes and may contribute to the onset of PDN
Development of Calcined-Clay and Hemp Hurd Composites for Construction
No full textThis research combines two alternative building materials in novel ways to create construction products that address current global challenges. Geopolymer cement is emerging as a high-performance, lower-impact alternative to ordinary Portland cement. It can provide equal or better strength and durability without producing considerable CO2 emissions. Calcined clays are beneficial precursors due to their mineral properties and abundance, as well as mitigating future supply challenges that may come from shifting industrial activity. Additionally, hemp hurd is gaining popularity in construction for its thermal and hygroscopic properties. This inner core of the plant’s stalk is most used with Lime binder as a moisture buffering natural insulator, which also offers the added benefit of removing carbon dioxide from the atmosphere during its rapid growth. The downside of hemp-lime insulation is that it is non-load bearing and requires structural framing. In phase one of this study, two calcined-clay-based geopolymer cement pastes were developed. In phase two, the better-performing binder was paired with hemp hurd in three different ratios to examine the thresholds of adequate compressive strength and thermal performance. Mechanical performance and thermal conductivity were examined alongside a binder-only control. Additionally, minor characterization and durability trials were performed to gain insight into this understudied material combination. Results indicated that hemp hurd with geopolymer binder could meet both compressive strength and thermal conductivity expectations, only at very different ratios. This suggests the possibility of functionally graded composites made with only geopolymer cement paste and hemp hurd which can fit a variety of construction applications
HEALTH IMPACTS, AIR POLLUTION AND ELECTRIC VEHICLES IN CALIFORNIA
No full textThis research examines the impact of electric vehicles (EVs) on air quality in California over the period from 2010 to 2021, as well as the implications of air pollution for respiratory health, organized into five chapters. The initial chapter provides background information and outlines the objectives, findings, and contributions. The second chapter examines the relationship between air quality and electric vehicles by utilizing fixed effect panel regression models. The third chapter employs panel regressions with Poisson control models to assess the correlation between changes in air quality resulting from electric vehicles and the prevalence of respiratory diseases. The fourth chapter evaluates the economic implications and advantages linked to the extensive implementation of EVs. The concluding chapter synthesizes the findings from the previous chapters. This study indicates that the widespread implementation of electric vehicles may have the capacity to substantially enhance air quality in California and reduce health hazards linked to air pollution
Analyzing Environmental Health: Air Pollution and Human Health Using Geospatial Data Science
No full textAir pollution from industrial emissions and wildfire smoke poses growing threats to public health. This dissertation employs geospatial data science to examine these challenges through three interrelated studies. The first study investigates the relationship between maternal residential exposure to industrial pollutants and low birth weight, identifying five chemicals as significant risk factors. The second study assesses the impact of industrial air pollution on lung and bronchus cancer survival, finding that exposure to 1,1,1-trichloroethane and cobalt is associated with reduced survival. The third study explores disparities in wildfire smoke PM2.5 exposure and its association with asthma exacerbations. Results show disparities of exposure to wildfire smoke among different subgroups, and significant relationships were observed between exposure to wildfire smoke and asthma exacerbation. Collectively, these findings underscore the urgent need for improved exposure assessment, targeted public health strategies, and promote equity in the face of industrial development and wildfire events