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Identifying molecular components of a fertility pathway
No full textReproductive failure is a common problem which deeply impacts those affected. Many will, unfortunately, never learn any potential cause for this issue. Treatment for reproductive complications are limited due to the lack of understanding of the molecular pathways associated with fertility, especially due to the limitations placed on studies focusing on reproductive health. Model organisms can thus be used in order to gain a better understanding of the pathways that modulate fertility in multicellular organisms. C. elegans are a common model organism notable for their large brood size, short lifespan, and affordable maintenance. They also share much of their genetic makeup with humans, notably the pam-1 gene which codes for the PAM-1 enzyme. Mutations in the pam-1 gene have been found to be detrimental to embryogenesis and fertility within C. elegans. Despite the knowledge that this highly conserved gene has these major impacts on fertility, little research has been done to uncover the molecular pathways associated with this gene. This project aims to utilize biochemical coimmunoprecipitation techniques in order to isolate novel proteins associated with the PAM-1 enzyme, with the ultimate goal to identify the specific pathways through which PAM-1 governs fertility
Alexis Love, MSU Athletic Hall Of Fame 2019 (5)
No full texthttps://digitalcommons.murraystate.edu/oh-murray-state-women/1001/thumbnail.jp
Harriet Withers, MSU Athletic Hall Of Fame (3)
No full texthttps://digitalcommons.murraystate.edu/oh-murray-state-women/1014/thumbnail.jp
Vivian Hale, The Murray State Shield 1959 pg. 104
No full texthttps://digitalcommons.murraystate.edu/oh-murray-state-women/1048/thumbnail.jp
Cleo G. Hester, The Murray State Shield 1950 pg. 17
No full texthttps://digitalcommons.murraystate.edu/oh-murray-state-women/1056/thumbnail.jp
Jill Doty Misner, The Murray State Shield 1990 pg. 124
No full texthttps://digitalcommons.murraystate.edu/oh-murray-state-women/1078/thumbnail.jp
Jill Doty Misner, The Murray State Shield 1989 pg. 98
No full texthttps://digitalcommons.murraystate.edu/oh-murray-state-women/1079/thumbnail.jp
Determining the Relationship Between Phosphorus and Blue-Green Algae Phycocyanin in Western Lake Erie Algal Blooms
No full textAlgal blooms have shown to be detrimental in the Western Lake Erie area in recent years. These algal blooms have proven to be extremely harmful to both public and environmental health, and a definitive cause of these blooms has yet to be found. Determining the parameters of the water in Western Lake Erie is key to finding the reason behind these harmful algal blooms. Harmful algal blooms are not only unsightly, but cause many issues for the people and wildlife in the area, including causing hypoxia and ultimately decimating the fish populations. Data from NOAA’s live-time buoy monitoring systems was collected from late August 2020 through 2024. The data collected included the phosphorus and blue-green phycocyanin levels as the primary focus for this study, but levels for pH, turbidity, and water temperature were also taken. No significant relationship was found between phycocyanin and phosphorus, as the levels were then analyzed using linear regression and showed phycocyanin and phosphorus as being statistically insignificant, with a p-value of 0.58. However, the relationships between phycocyanin and the respective pH, turbidity, and water temperature all proved to be statistically significant with p-values \u3c 0.05. Multiple regression analysis also revealed a significant relationship between phycocyanin and pH with turbidity, with an R2 value of 0.87 and a p-value \u3c 0.05. Research such as this could be the key to eliminating harmful algal blooms in this area, leading to a healthier public and ecosystem in Western Lake Erie
Understanding temporal changes in plant leaf traits of native and non-native Kentucky plants using long-term herbarium records
No full textHerbarium specimens are the most valuable, verifiable, and sustainable records to study the impacts of climate change on the biota. Temporal herbarium data can provide critical information on how species respond to changes in habitat conditions by tracking changes in species’ morphological and phenological traits. This study aims to use Japanese Honeysuckle (Lonicera Japonica) and Common Greenbrier (Simlax rotundifolia) to assess the impact of climate change on invasive and native plants. Further study of these changes can provide vital understanding of how the environment is adapting to major climate change and can even possibly help us know where to focus our efforts to work against global warming
Systematic Leaf Morphology Based on Anatomical Attributes of Members of the Arum Family (Araceae)
No full textThe recent literature concerning the Arum family (Araceae) has grown in number over the past few years, correlating with a rise of their popularity as ornamental houseplants (Haigh et al, 2023). However, I find that literature concerning the anatomical development and morphology of leaves across the family in a comparative study is lacking (Keating, 2002). Currently, within my own personal collection and the shared teaching collection at Murray State University, I have the opportunity to sample a significant representation of species across the family. Through harvesting, sectioning, mounting on a slide, and observation of leaf anatomical structure via a compound microscope, this study aims to provide a comparative anatomy of leaf structure across intrafamilial clades. In doing so, this study also aims to provide an insight into the differences in leaf structure across genera and to highlight the diversity therewithin. Following Yeung’s protocol (1998), I amassed 48 unique specimens and sectioned fresh material using a hand microtome. The key areas of study for this project are the leaf midrib and petiole, as well as including longitudinal sections of the leaf tip to describe hydathodes. The sections are then stained using 1% TBO suspended in a pH=4.4 benzoate buffer and mounted on slides for observation under light microscopy. Microscope images are then to be photographed of key structures throughout the sample, including vascular bundles, chlorenchyma, aerenchyma/mucilage ducts, epidermis, and calcium oxalate crystals. In the present progress of this study, I have noticed differences in the structure and number of vascular bundles, mucilage cells, calcium oxalate crystals, and other overall anatomical features of different species. I plan to examine these differences further and present how structures have changed from more basal to more recent species evolutionarily