1025 research outputs found
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Effect of Raspberry Ketone on Adipogenesis and Lipolysis in 3T3-L1 Mouse Preadipocytes
The prevalence of obesity in the United States has seen a sharp increase since the mid-twentieth century, which has led to increased research on the process of adipogenesis, or the differentiation of preadipocytes to mature adipocytes. The 3T3-L1 cell line is a mouse preadipocyte used to study the underlying mechanisms of adipogenesis. Raspberry ketone (4-(4-hydroxyphenyl) butan-2-one; RK) is a naturally occurring compound found in red raspberries and is often present in weight loss supplements. RK has a structure that is similar to other compounds, such as capsaicin and synephrine, that are known to both inhibit adipogenesis and enhance lipolysis. To test the effect of RK on adipogenesis, 3T3-l1 preadipocytes were treated with an adipogenesis inducing treatment containing IBMX, insulin, and dexamethasone. RK solutions of 200 mM, 300 mM, and 400 mM RK were added to the adipogenesis inducing treatment, and the cells were allowed to mature for eight days. In order to test rates of lipolysis, the cells were treated with the adipogenesis inducing treatment for eight days, and then given the same 200 mM, 300 mM, and 400 mM RK treatment on day eight. The cells were given this treatment for six days. To quantify rates of adipogenesis and lipolysis, Oil Red O staining was used. Western blotting was used to identify the presence of two key proteins involved in adipogenesis and lipolysis, such as Fatty Acid Binding Protein 4 (FABP4) and Peroxisome Proliferator-activated Receptor Gamma (PPARγ). RK is expected to both inhibit adipogenesis and increase lipolysis in a concentration dependent manner, resulting in lower levels of FABP4 and PPARγ expression. Gaining a deeper understanding of the effects of different compounds such as RK on obesity may allow the translation of these lab practices to a clinical setting and help combat the growing obesity epidemic
Authenticity in the Classroom
Inquiry-based teaching strategies focus on the natural discovery of learning. While the importance of testing has taken over a majority of the classroom, I think focusing more on the students and how to make learning more appealing to them is what will drive the most success. In higher education and enrichment programs you often hear of STEM or STEAM which are two programs that connect different academic contents with a hands on approach. The value of doing so is giving the students the independence to learn and also creating a work environment that allows for self discovery
Changes in Alcohol and Cannabis Use Related to Impulsivity Throughout College
This study investigates the relationship between impulsivity and alcohol and cannabis use among college students. 168 undergraduate students completed a computerized version of the Iowa Gambling Task (IGT) as well as a paper questionnaire including the Barratt Impulsivity Scale (BIS), Alcohol Use Questionnaire, and the Adult Cannabis Problems Questionnaire. We hypothesize that 1) students with more frequent alcohol use and more problematic cannabis use will exhibit higher levels of impulsivity and will be more likely to pick disadvantageous cards in the IGT 2) students who are more problematic cannabis users will show more frequent alcohol use, and 3) impulsivity will increase as years in school increase for those who exhibit more frequent alcohol and cannabis use
How Ethical Parent-Teacher Relationships Affect Student Success
An ethical parent-teacher relationship can positively impact a student’s success in their elementary school years and I wanted to incorporate this into my student teaching placements. In today’s technological era, there are many more opportunities for parents to be able to communicate with their student\u27s teacher in order to help the student than in the past. If parents have access to technology to communicate with their child’s teacher, both teachers and parents should be proactive in making an effort to form an ethical relationship in order to establish an open line of communication from the start of the school year. This poster presentation highlights how implementing ethical parent-teacher relationships impacted my student teaching experience
The Effects of Parent Attachment and Parenting Styles on Decision-Making in College Students
College students face many decisions that can shape the course of their future lives. The impact of personality on decision-making is well researched; little research explores the impact of parent attachment and parenting styles. Students (N = 80) at a small liberal arts university participated in a survey study that explored the effects of two personality variables, parent attachment, and parenting styles on decision-making in college students. We hypothesized that high levels of conscientiousness, impulse control, and authoritative parenting, and low levels of attachment anxiety and avoidance, would predict positive decision-making styles. Regression analyses revealed that results for conscientiousness, impulse control, and attachment avoidance were consistent with predictions. Parenting styles also emerged as predictors but not always in the expected direction. Our regressions explained 23%-36% of the variance for four of the five decision-making styles. We believe the impact of parent attachment and parenting styles on decision-making warrants further exploration
Adolescent Literacy Resource Menu: A Guide for Instructional Leaders
This guide is organized by commonly experienced challenges (e.g., lack of modeling) to teachers implementing evidence-based adolescent literacy practices with fidelity. Also provided are an explanation of each challenge and resources from established organizations and research centers that instructional leaders can use to address these challenges. Some of these resources are brief documents that a teacher can quickly scan; others are lengthier and may require more time to read and make sense of. Many of the resources are free (e.g., online resources), and some have an associated cost (e.g., books). This guide provides an estimate of the cost and time associated with each resource
#MeToo: A Case Study in Re-Embodying Information
This article examines the feminist hashtag #MeToo. Like other feminist hashtags, #MeToo responds to public misunderstanding,disbelief, or complacency surrounding violence against women. This problem, I argue, is in part a byproduct of digital informationsharing that separates bodies from the information that represents them, and cultural understandings of sexual assault and harassmentthat support rape culture. I draw on a new materialist approach, infused with feminist information studies, to examine the ways inwhich #MeToo acts as a rhetorical census that re-embodies information and resists rape culture.© 2019 Elsevier Inc. All rights reserved
Examining female entrepreneurial firms: can we predict growth orientation?
Both regional and global evidence presents a positive picture of increased entrepreneurial activity among females, and highlights, in particular, the rise in the rate of early stage entrepreneurs across both developed and emerging nations. However, it appears that s significant percentage of female-owned organizations remain small in size, with limited growth. Traditional growth models seem unable to account for this phenomenon and do not consider differences in gender as causal factor. Consequently, this paper examines the growth orientation of female-owned firms in Ireland. Specifically, it identifies the factors that impact this process and provides clarity on predicting the growth trajectories based upon these entrepreneurial and organizational factors. As such, it aims to provide a mechanism to predict and stimulate high growth business among female entrepreneurs both within Ireland and across similar countries
Music and Ethics: Ethical Decision Making and Treatment of Provocative Musical Works by Collegiate Ensembles
An arising problem in post-secondary music education is defining where the academic freedom of a professor ends and students’ rights to make their own decisions begin regarding ensemble performances. This research outlines potential problems that may ignite this question including when a student has an objection to a composer whose personal or political beliefs or actions may be considered questionable, an objection to a piece that may have extra-musical political implications, an objection to a piece that may constitute cultural appropriation, and/or an objection to a piece that may be proselytizing. Analytical tools are presented so that when this may happen, professors and students have several resources to assist in making ethical decisions. Specific musical works, including Bach’s St. John Passion, will be discussed in the context of ethical controversy
Growth as a mechanism of defense in Phaseolus lunatus
Plants use mechanisms of defense to combat herbivory. Extrafloral nectary (EFN) production is a form of defense present in lima bean (Phaseolus lunatus) which is positively correlated with herbivory. The plant produces nectar through EFNs which attracts the enemy of the herbivore trading food for protection. However, plants have limited resources, so they must allocate energy to their best bet of fitness. This explains why heavily damaged plants may allocate to another defense mechanism or to growth instead. In vining plants, it is common to use growth as a foraging method. For example, plants grow towards sunlight in a dark environment to increase the sunlight they receive. In this likeness, it is interesting to consider growth to evade herbivory as a defense mechanism. If Phaseolus lunatus invest in growth to evade herbivory, a high degree of herbivory damage would result in them having less EFNs and higher internode lengths than a those experiencing a low degree of herbivory. This phenomenon was tested by an 8-week experimental study in which Phaseolus lunatus was damaged in four treatments: 0%, 20%, 50%, and 80% and the internode lengths, height, leaf number, and EFN numbers were measured before and after damage. From this experiment, the idea of growth as a form of defense was supported by lower EFN numbers per leaf and higher internode lengths in the 50 and 80% damage groups when compared to the EFN numbers per leaf in the 0 and 20% damage groups