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Guest Artist Series: Clelia Iruzan & Michael Gurt (2023)
Get PDFSNC Music Department presents: a Guest Artist Series Performance featuring Two Pianists, Clelia Iruzan & Michael Gurt (2023)
Summer 2023: Africa Seminar’s Focus on Biology Evolves Into Something Bigger
Get PDFThe SNC Global Seminar trip to the African nation of Namibia in May was originally designed to focus on wildlife conservation. But since its inception in 2019, it’s become a course that opens eyes to topics far beyond nature and science, to include poverty, politics, health, communication, relationships and culture.https://digitalcommons.snc.edu/snc_magazine_archives_2019-2023/1001/thumbnail.jp
June 2023
Get PDFIn this issue: SNC to Break Ground on Business Building With Gift From Schneider Family Remembering President Emeritus William Hynes Elementary Students Get a Crash-course in Human Anatomy A Vocation by Association: “I Found My Place and Made the Most of It” In Photos: Commencement 202
Mikaela Benitez: Senior Art Exhibition Portfolio
Get PDFThis document represents the Senior Art Exhibition portfolio of Mikaela Benitez, which was exhibited in the Bush Art Center Galleries in the spring semester of 2023.https://digitalcommons.snc.edu/artportfolios/1080/thumbnail.jp
Mortal Remains as Biohazard: Chinese Repatriation, Plague Epidemiology, and Biopolitical Governance in Sài Gòn–Chợ Lớn, 1890–1898
No full textThis article examines French efforts to disrupt the transfer of 2000 Chinese remains from Sài Gòn-Chợ Lớn to Hong-Kong in 1892. French officials cited bio-hazardous threats as grounds for legal interdiction, infuriating Cantonese leaders who demanded the removal of bureaucratic obstacles to repatriations. Situating French epidemiology in a global bubonic outbreak, this article shows how colonial panic activated a racialized biopolitics that demonized Chinese “bodies” as plague-borne menaces and justified its drastic measures. As inter-imperial competitions for biomedical research intensified, transnational Chinese practices, perceived as undermining public health initiatives, became a flashpoint of conflicts over hygiene, mobility, and inter-ethnic interactions.https://digitalcommons.snc.edu/faculty_staff_works/1055/thumbnail.jp
LPS as a virulence factor of Burkholderia cepacia during plant and human infection
No full textBurkholderia cepacia is a gram-negative bacterium that is the causative agent of sour skin rot in onion crops, and is an opportunistic pathogen in patients with cystic fibrosis. There are limited treatments available for this bacterium due to its innate resistance to antibiotics, and its virulence mechanisms are not well understood. This work aims to identify and describe virulence factors necessary for B. cepacia pathogenesis. Transposon mutagenesis in B. cepacia ATCC 25416, followed by a virulence screen in an onion infection model identified mutants that generated smaller wounds at 24 hours post-infection. We chose to follow up on mutant 169 and determined that the transposon inserted in the rfbB gene of chromosome one. Expression analysis suggested that the entire rfbBDCE operon is likely disrupted. rfbB is homologous to genes encoding glucose dehydratase, an enzyme in the lipopolysaccharide (LPS) biosynthesis pathway. Production of altered LPS was confirmed in the mutant, and current work is focused on determining whether this disruption affects the pathogen’s ability to interact with host cells. Initially, we focused on designing a bacterial adhesion and invasion assay in the onion host, but this model proved inconsistent. We are currently developing a new assay using a human epithelial cell line with the goal of determining whether the altered LPS impedes binding and/or invasion into host cells. This quantitative assay will be supplemented with direct visualization of bacterial binding and invasion using confocal microscopy. Together, these data establish the B. cepacia rfbBDCE operon as critical for virulence.https://digitalcommons.snc.edu/collaborative_presentations/1095/thumbnail.jp
