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    Using Crowdsourced Exercises for Vocabulary Training to Expand ConceptNet

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    In this work, we report on a crowdsourcing experiment conducted using the V-TREL vocabulary trainer which is accessed via a Telegram chatbot interface to gather knowledge on word relations suitable for expanding ConceptNet. V-TREL is built on top of a generic architecture implementing the implicit crowdsourding paradigm in order to offer vocabulary training exercises generated from the commonsense knowledge-base ConceptNet and – in the background – to collect and evaluate the learners’ answers to extend ConceptNet with new words. In the experiment about 90 university students learning English at C1 level, based on Common European Framework of Reference for Languages (CEFR), trained their vocabulary with V-TREL over a period of 16 calendar days. The experiment allowed to gather more than 12,000 answers from learners on different question types. In this paper we present in detail the experimental setup and the outcome of the experiment, which indicates the potential of our approach for both crowdsourcing data as well as fostering vocabulary skills

    Wideband Collaborative Spectrum Sensing Using Massive MIMO Decision Fusion

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    In this paper, in order to tackle major challenges of spectrum exploration & allocation in Cognitive Radio (CR) networks, we apply the general framework of Decision Fusion (DF) to wideband collaborative spectrum sensing based on Orthogonal Frequency Division Multiplexing (OFDM) reporting. At the transmitter side, we employ OFDM without Cyclic Prefix (CP) in order to improve overall bandwidth efficiency of the reporting phase in networks with high user density. On the other hand, at the receiver side (of the reporting channel) we device the Time-Reversal Widely Linear (TR-WL), Time-Reversal Maximal Ratio Combining (TR-MRC) and modified TR-MRC (TR-mMRC) rules for DF. The DF Center (DFC) is assumed to be equipped with a large antenna array, serving a number of unauthorized users competing for the spectrum, thereby resulting in a “virtual” massive Multiple-Input Multiple-Output (MIMO) channel. The effectiveness of the proposed TR-based rules in combating (a) inter-symbol and (b) inter-carrier interference over conventional (non-TR) counterparts is then examined, as a function of the Signal-to-Interference-plus-Noise Ratio (SINR). Closed-form performance, in terms of system false-alarm and detection probabilities, is derived for the formulated fusion rules. Finally, the impact of large-scale channel effects on the proposed fusion rules is also investigated, via Monte-Carlo simulations

    Beyond the Medical Model: Thinking Differently about Medical Education and Medical Education Research

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    Issue: In medical education, teaching is currently viewed as an intervention that causes learning. The task of medical education research is seen as establishing which educational interventions produce the desired learning outcomes. This ‘medical model’ of education does not do justice to the dynamics of education as an open, semiotic, recursive system rather than a closed, causal system. Evidence: Empirical ‘evidence’ of ‘what works’ – that is, what is supposed to affect ‘learning’ – has become the norm for medical educational improvements, where generalized summary outcomes of research are often presented as must-follow guidelines for myriad future educational situations. Such investigations of educational processes tend to lack an explicit engagement with the purposes of medical education, which we suggest to understand in terms of qualification (the acquisition of knowledge, skills, and understanding), socialization (becoming a member of the professional group) and subjectification (becoming a thoughtful, independent, responsible professional). In addition, investigations of educational processes tend to rely on causal assumptions that are inadequate for capturing the dynamics of educational communication and interaction. Although we see an increasing acknowledgement of the context-dependency of teaching practices toward educational aims, the currently prevailing view in medical education and educational research limits understanding of what is actually going on when educators teach and students participate in medical education – a situation which seriously hinders advancements in the field. Implications: In this paper, we hope to inform discussion about the practice of medical education by proposing to view medical education in terms of three domains of purpose (professional qualification, professional socialization, and professional subjectification) and with full acknowledgement of the dynamics of educational interaction and communication. Such a view implies that curriculum design, pedagogy, assessment, and evaluation should be reoriented to include and integrate all three purposes in educational practice. It also means that medical education research findings cannot be applied in just any teaching context without carefully considering the value of the suggested courses of actions toward the particular educational aims and teaching setting. In addition, medical educational research would need to investigate all three purposes and recognize the openness, semiotic nature, and recursivity of education in offering implications for teaching practice

    Precarious professionality: graduate outcomes and experiences from an Initial Teacher (Further) Education programme in Ireland

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    This article presents and discusses the findings of a small-scale research project into the occupational outcomes of graduates of an Initial Teacher (Further) Education (ITE) programme at Maynooth University in Ireland. The findings from this mixed-method research indicate that many graduates experience high levels of occupational precarity and a sense of professional inequity when compared with their compulsory education teacher-peers as they attempt to make the transition into the heterogeneous field of adult and Further Education in Ireland

    ‘When it comes to what employers are looking for, I don’t think I’m it for a lot of them’: class and capitals in, and after, higher education

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    Much research on adults in higher education has focused on issues of access and participation. As a result little is known about what happens to working-class students after leaving university even though employability is high on the agenda HE research on this topic in relation to such students is sparse. This research focuses on the voices of working-class students and their aspirations in relation to employability. Using two student narratives this paper draws on the findings of two countries, England and Ireland, from a six-country European project on employability of non-traditional students using biographical research methods. Their stories reveal an awareness of class inequalities in the labour market in relation to cultural, economic and social capital and issues of locality, gender and age. The stories also indicate a sense of precarity in their lifecourse in a society which has become highly reflexive and fluid (Alheit, P., and B. Dausien. 2002. “The ‘Double Face’ of Lifelong Learning: Two Analytical Perspectives on a ‘Silent Revolution’.” Studies in the Education of Adults 34 (1): 3–23)

    Proteomic investigation of interhyphal interactions between strains of Agaricus bisporus

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    Hyphae of filamentous fungi undergo polar extension, bifurcation and hyphal fusion to form reticulating networks of mycelia. Hyphal fusion or anastomosis, a ubiquitous process among filamentous fungi, is a vital strategy for how fungi expand over their substrate and interact with or recognise self- and non-self hyphae of neighbouring mycelia in their environment. Morphological and genetic characterisation of anastomosis has been studied in many model fungal species, but little is known of the direct proteomic response of two interacting fungal isolates. Agaricus bisporus, the most widely cultivated edible mushroom crop worldwide, was used as an in vitro model to profile the proteomes of interacting cultures. The globally cultivated strain (A15) was paired with two distinct strains; a commercial hybrid strain and a wild isolate strain. Each co-culture presented a different interaction ranging from complete vegetative compatibility (self), lack of interactions, and antagonistic interactions. These incompatible strains are the focus of research into disease-resistance in commercial crops as the spread of intracellular pathogens, namely mycoviruses, is limited by the lack of interhyphal anastomosis. Unique proteomic responses were detected between all co-cultures. An array of cell wall modifying enzymes, plus fungal growth and morphogenesis proteins were found in significantly (P < 0.05) altered abundances. Nitrogen metabolism dominated in the intracellular proteome, with evidence of nitrogen starvation between competing, non-compatible cultures. Changes in key enzymes of A. bisporus morphogenesis were observed, particularly via increased abundance of glucanosyltransferase in competing interactions and certain chitinases in vegetative compatible interactions only. Carbohydrate-active enzyme arsenals are expanded in antagonistic interactions in A. bisporus. Pathways involved in carbohydrate metabolism and genetic information processing were higher in interacting cultures, most notably during self-recognition. New insights into the differential response of interacting strains of A. bisporus will enhance our understanding of potential barriers to viral transmission through vegetative incompatibility. Our results suggest that a differential proteomic response occurs between A. bisporus at strain-level and findings from this work may guide future proteomic investigation of fungal anastomosis

    FISHing in fungi: Visualisation of mushroom virus X in the mycelium of Agaricus bisporus by fluorescence in situ hybridisation

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    Agaricus bisporus is a commercial mushroom crop susceptible to a disease caused by a complex of viruses known collectively as mushroom virus X (MVX). Symptoms of MVX include bare patches and mushroom cap discolouration (browning) in the fruiting bodies, phenotypes associated with the viruses AbV6 and AbV16, respectively. Limited understanding exists of the localisation and mobilisation of these viruses within the mycelium of A. bisporus. To this end, a non-destructive fluorescence in situ hybridisation (FISH) method was developed for in situ targeting of AbV6 and AbV16 in A. bisporus mycelium. An MVX strain associated with the bare patch disease phenotype revealed predominantly high signal towards the growing edges of cultures when probed for AbV6, with a ‘halo-effect’ of high signal intensity around putative vacuoles. An MVX strain associated with the browning disease phenotype showed high signal intensities within reticulating networks of hyphae in a highly compartmentalised manner when probed for AbV16. Localisation of the two viruses in MVX-infected cultures appears independent, as both viruses were found in completely discrete areas of the mycelium in differential patterns. FISH detected low level presence of the two viruses, AbV6 and AbV16 in a number of cultures which had tested negative for the viruses by RT-PCR. This suggests that FISH may be more sensitive at detecting viruses at low levels than molecular methods. This study demonstrates that FISH is a powerful tool in the field of mycovirology

    Chemical novelty facilitates herbivore resistance and biological invasions in some introduced plant species

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    Ecological release from herbivory due to chemical novelty is commonly predicted to facilitate biological invasions by plants, but has not been tested on a community scale. We used metabolomics based on mass spectrometry molecular networks to assess the novelty of foliar secondary chemistry of 15 invasive plant species compared to 46 native species at a site in eastern North America. Locally, invasive species were more chemically distinctive than natives. Among the 15 invasive species, the more chemically distinct were less preferred by insect herbivores and less browsed by deer. Finally, an assessment of invasion frequency in 2,505 forest plots in the Atlantic coastal plain revealed that, regionally, invasive species that were less preferred by insect herbivores, less browsed by white‐tailed deer, and chemically distinct relative to the native plant community occurred more frequently in survey plots. Our results suggest that chemically mediated release from herbivores contributes to many successful invasions

    Development and validation of a real-time microelectrochemical sensor for clinical monitoring of tissue oxygenation/perfusion

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    Oxygen is of critical importance to tissue viability and there is increasing demand for its reliable real-time clinical monitoring in order to prevent, diagnose, and treat several pathological disorders, including hypoxia, stroke and reperfusion injury. Herein we report the development and characterisation of a prototype clinical O2 sensor, and its validation in vivo, including proof-of-concept monitoring in patients undergoing surgery for carpal tunnel release. An integrated platinum-based microelectrochemical device was custom designed and controlled using a miniaturised telemetry-operated single channel clinical potentiostat. The in vitro performance of different sensor configurations is presented, with the best sensor design (S2) displaying appropriate linearity (R2 = 0.994) and sensitivity (0.569 ± 0.022 nA μM−1). Pre-clinical validation of S2 was performed in the hind limb muscle of anaesthetised rats; tourniquet application resulted in a significant rapid decrease in signal (90 ± 27%, [ΔO2] ca. 140 ± 18 μM), with a return to baseline within a period of ca. 3 min following tourniquet release. Similar trends were observed in the clinical study; an immediate decrease in signal (39 ± 3%, [ΔO2] ca. 30 ± 20 μM), with basal levels re-established within 2 min of tourniquet release. These results confirm that continuous real-time monitoring of dynamic changes in tissue O2 can serve as an indicator of reperfusion status in patients undergoing carpal tunnel surgery, and suggests the potential usefulness of the developed microelectrochemical sensor for other medical conditions where clinical monitoring of O2 and perfusion is important

    Beyond VoF: alternative OpenFOAM solvers for numerical wave tanks

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    The vast majority of numerical wave tank applications are solved using finite volume-based, volume of fluid methods. One popular numerical modelling framework is OpenFOAM and its two phase solvers, interFoam and interIsoFoam, enabling the simulation of a broad range of marine hydrodynamic phenomena. However, in many applications, certain aspects of the entire set of possible hydrodynamic phenomena are not of interest and the reduced complexity could allow the use of simpler, more computationally efficient solvers. One barrier for the application of such alternative solvers is the lack of suitable wavemaking and absorption capabilities, which this paper aims to address. A wavemaking and absorption methodology is presented, which can be applied to different solvers using the same fundamental concept. The implementation is presented for interFoam and interIsoFoam, as well as two other solvers whose use as numerical wave tanks has not previously been reported in the literature, shallowWaterFoam and potentialFreeSurfaceFoam. Parameter studies are performed to guide the user in the use of the methods. Example applications for two industrially relevant test cases are demonstrated; a multi-frequency wave packet focused at one position over flat bottom and regular waves propagating over a submerged shoal. All solvers yielded useful results, but some complex wave transformations in the shoal case were only resolved by the VoF methods. Alternative methods beyond the already well established VoF methods seem worth considering because potential for significant reductions in computational effort exist

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