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    Consumers' perceived value of healthier eating: A SEM analysis of the internalisation of dietary norms considering perceived usefulness, subjective norms, and intrinsic motivations in Singapore

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    Consumers' internalisation of social norms is at work when they make routine, healthier food choices in everyday contexts. We investigate the dynamics of this phenomenon in Singapore, where over 98% of consumer food products are imported. To study this, we propose, through a consumer perspective (n = 316) via Partial Least Squares Structural Equation Modelling (PLS-SEM), a model that establishes a positive relationship between perceived usefulness, subjective norms, and intrinsic motivations and the perceived value of healthier food. Subjective norms are themselves found to be a function of perceived barriers, facilitating conditions and personal innovativeness. Our framework contributes to establish a shift in the drivers of healthier food choices toward a more socio-culturally grounded decision-making approach that is particularly relevant to understand food consumption. We show that daily food routines (opposing the exceptional healthy food item) are encapsulated in perceived value of healthier eating. The data indicates further that to support healthier food product consumption, both policy makers and food providers must facilitate imported foods that meet quickly changing lifestyle requirements

    Space-Time Spreading Aided Distributed MIMO-WSNs

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    In this letter, we consider the plaguing, yet rarely handled problem of interference resulting from superposition of multiple sensor signals in time, when sent over a multiple access channel (MAC) in wireless sensor networks (WSNs). We propose space-time spreading (STS) of local sensor decisions before reporting them over a MAC to i) minimize interference and ii) reduce energy required for combating interference due to superposition of sensor decisions. Each sensor decision is encoded on appropriately indexed space-time block of fixed duration using dispersion vectors, such that a single sensor is activated over each space-time block while all the other sensors are silent. At the receive side of the reporting channel, we assume a multi-antenna decision fusion center (DFC), thereby representing a distributed multiple-input-multiple-output (MIMO) communication scenario. We formulate and compare optimum and sub-optimum fusion rules for fusing sensor decisions at the DFC to arrive at a reliable conclusion. Simulation results demonstrate gain in fusion performance with STS-aided transmission by 3 to 6 times over performance without STS

    Amóinia? Amóinia? Cad faoi Amóinia?

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    This is a comic aimed at children from the age of eight upwards. It highlights impacts from ammonia in agriculture, plus sources and solutions to the problem

    Risk Factors for Self-Harm: Narratives from a Sample of Young People in Northern Ireland

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    Self-harm continues to be a growing concern within adolescence and is a globally recognised public health and social problem. Adolescents living in the community who self-harm are extremely common however less is known about these young people. This study focussed on capturing the voice of young people who engage in cutting behaviour to provide insight into the risks associated with this phenomenon. Single semi-structured interviews were conducted with 9 adolescents aged 16–18 years who lived within one Trust area in Northern Ireland. Thematic analysis was applied to the transcribed interviews in which themes emerged. The three subordinate themes of onset, persistence and ending of the behaviour encompassed six sub-themes which were further identified as risk factors for the behaviour. Risk factors identified were: ACE’s, poor relationships and difficulties in support networks, exposure to self-harm, psychological issues, “addiction” to self-harm, concealment of harming behaviour—to control and professional and peer support that helps or hinders. These factors support the current literature base however individual and diverse explanations are highlighted which provide further depth, particularly around the concept of addiction and support that hinders young people. Despite the small nature of the study, recommendations for social work practice, clinical practice and other relevant professional practice as well as future research are considered in view of the findings. Key direction outlines the importance of building trusting relationships, continuity of care and continuing to listen to young people as vital to the helping relationship

    Energy‐maximising moment‐based constrained optimal control of ocean wave energy farms

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    Successful commercialisation of wave energy technology inherently incorporates the concept of an array of wave energy converters (WECs). These devices, which constantly interact via hydrodynamic effects, require optimised control that can guarantee maximum energy extraction from incoming ocean waves while ensuring, at the same time, that any physical limitations associated with device and actuator systems are being consistently respected. This paper presents a moment-based energy-maximising optimal control framework for WECs arrays subject to state and input constraints. The authors develop a framework under which the objective function (and system variables) can be mapped to a finite-dimensional tractable quadratic program (QP), which can be efficiently solved using state-of-the-art solvers. Moreover, the authors show that this QP is always concave, i.e. existence and uniqueness of a globally optimal solution is guaranteed under this moment based framework. The performance of the proposed strategy is demonstrated through a case study, where (state and input constrained) energy-maximisation for a WEC farm composed of CorPower-like WEC devices is considere

    Rotors for wave energy conversion—Practice and possibilities

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    This review studies some of the existing ideas which create a fundamentally new direction for wave energy converter (WEC) development, obtaining energy from the elliptical motion of particles in water waves using a rotor. The review focuses on three main aspects of rotor-based WECs: experimental study of the developed prototypes, derivation and development of the mathematical models, and control effectors and philosophies for the proposed devices. The range of developed small scale prototypes and their experimental studies are presented. The shortcomings of the current mathematical and hydrodynamic models are identified, while an overview of the proposed and new possible control effectors and strategies is conducted. This allows us to see the state of the development of the different concepts and problems to be solved in bringing wave energy rotors to operational reality

    Experimental Implementation and Validation of a Broadband LTI Energy-Maximizing Control Strategy for the Wavestar Device

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    This study addresses the experimental validation of a linear time-invariant (LTI) energy-maximizing control strategy for wave energy converters (WECs), applied to a 1/20 scale Wavestar WEC. To fulfill this objective, system identification routines are utilized to compute a mathematical (parametric) model of the input–output dynamics of the device, suitable for control design and implementation. With this parametric model, the so-called LiTe-Con energy-maximizing strategy, recently published in the literature, is designed, synthesized, and tested under irregular wave excitation in the wave basin at Aalborg University. Given that the LiTe-Con requires instantaneous knowledge of the wave excitation effects, estimates are provided by means of an unknown-input Kalman filter, designed in close synergy with the so-called internal model principle. For the experimental assessment, both controller and estimator are directly implemented in a real-time architecture. The performance of the LiTe-Con is evaluated in terms of energy-absorption, showing consistent results with respect to those obtained in numerical simulation, hence validating the LiTe-Con controller in a realistic real-time scenari

    Towards efficient extremum-seeking control of wave energy systems: possibilities and pitfalls.

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    Given its success in other renewable energy domains, such a solar and wind, extremum-seeking control (ESC) would seem to be a promising candidate for the wave energy energy-maximising control domain. There are many advantages to ESC, principal among them the lack of a need for a mathematical system model, with effective wave energy hydrodynamic modelling being particularly challenging. However, a number of fundamental limitations of ESC for wave energy converters (WECs) can be found, with the panchromatic (stochastic) nature of the wave excitation a key issue, resulting in potentially long performance function evaluation times. This, combined with the desire to perform intra-wave control adjustment, creates a natural tension in the solution of the wave energy ESC problem. Motivated by this, we examine, in this paper, the fundamental opportunities and pitfalls of ESC for the wave energy control problem, providing a concise definition of WEC ESC and its characteristics. In particular, we investigate the intrinsic limitations behind ESC for the WEC control problem, and provide a potential set of future directions aiming at alleviating such disadvantages and directly contributing towards the development of efficient model-free control systems for wave energy device

    Mucosal Associated Invariant T Cells in Cancer-Friend or Foe?

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    Mucosal associated invariant T (MAIT) cells are a population of unconventional T cells which can bridge the innate and adaptive immune systems. Well-described roles for MAIT cells include host protection against invading bacteria, fungi and viruses. Upon activation, MAIT cells become prolific effector cells, capable of producing a range of cytokines and lytic molecules. In addition to their anti-microbial role, MAIT cells have been implicated in immune responses to cancer, with opposing beneficial and pathogenic roles reported. On the one hand, MAIT cells can home to the site of the tumour in many human cancers and can produce anti-tumour molecules. On the other, MAIT cells can display defective phenotypes in certain cancers and produce pro-tumour molecules. In this review, we discuss the current literature on the diverse roles for MAIT cells in cancer, outlining their frequencies, functions and associations with N staging and prognosis. We also discuss potential mechanisms underpinning cancer-related alterations in MAIT cells and highlight therapeutic approaches to harness or target MAIT cells in cancer

    IFN-γ and PPARδ Influence the Efficacy and Retention of Multipotent Adult Progenitor Cells in Graft vs Host Disease

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    Cell-based therapy for the treatment of inflammatory disorders has focused on the application of mesenchymal stromal cells (MSCs) and multipotent adult progenitor cells (MAPCs). Despite the recent positive findings in industry-sponsored clinical trials of MSCs and MAPCs for graft vs host disease (GvHD), cell therapy is efficacious in some but not all patients, highlighting the need to identify strategies to enhance cell-based therapeutic efficacy. Here, we demonstrate the capacity for interferon (IFN)-γ licensing to enhance human MAPC efficacy and retention following early administration in a humanized mouse model of acute GvHD (aGvHD). Activation of the nuclear receptor peroxisome proliferator-activated receptor delta (PPARδ) negatively influenced the retention and efficacy of human MAPCs as well as IFNγ-licensed MAPCs in the aGvHD model. PPARδ antagonism significantly enhanced the efficacy of human MAPCs when administered early in the humanized aGvHD model. COX-2 expression in human MAPC was significantly decreased in IFN-γ licensed MAPCs exposed to a PPARδ agonist. Importantly, MAPC exposure to the PPARδ antagonist in the presence of a COX-2 inhibitor indomethacin before administration significantly reduced the efficacy of PPARδ antagonized MAPCs in the aGvHD humanized mouse model. This is the first study to demonstrate the importance of PPARδ in human MAPC efficacy in vivo and highlights the importance of understanding the disease microenvironment in which cell-based therapies are to be administered. In particular, the presence of PPARδ ligands may negatively influence MAPC or MSC therapeutic efficacy

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