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Advising the Avengers: Guiding First-Generation College Students Through Their Hero\u27s Journey
Get PDFAdvising the Avengers: Guiding First-Generation College Students Through Their Hero\u27s Journey examines the parallels between the Heros Journey archetype and the experiences of first-generation college students (FGCS). Through pop culture references from notable figures like Harry Potter, Spider-Man, and Challa, this presentation highlights unique challenges faced by FGCS, including financial barriers, achievement guilt, hidden curriculum, and imposter syndrome. Academic advisors act as essential mentors akin to Yoda and Professor X\u27s offering guidance as students navigate their transformative journeys. This presentation equips advisors with insights into the Heros Journey framework, enhancing their ability to support FGCS in overcoming challenges and realizing their potential for success in higher education and beyond. By understanding these connections, advisors can play a vital role in fostering resilience and empowerment among FGCS. Join us to discover strategies that promote their growth and development
Brave Connections and Commitments: Retention Strategies That Affirm, Motivate, And Cultivate Cultural Wealth And Belonging For Men Of Color In Community College
No full textRetention of marginalized populations - students of color and students from low-income and/or first-generation families - remains a pervasive challenge across the nation, particularly for first-year men of color attending predominantly White community colleges. Despite efforts and best practices employed at institutions across the country, these strategies require a shift in professional practice that focuses on success factors that contribute to retaining men of color in higher education (Williams Jr, 2022). Research reveals that the first year of college can be challenging for all students, particularly first-generation populations. Men of color, in particular, encounter different issues in their pursuit of academic and social success; however, they too use various forms of community cultural wealth in their first year to overcome challenges. Using these forms of cultural wealth, Community College administrators can better support first-generation men of color as they persist academically
Building Community through a Novel Narrative Platform
Get PDFTo promote connection and community building within our diverse first-generation student community, the first-generation student chairs proposed and developed a student spotlight feature. This spotlight feature allows the student chairs to share their journey and build a network of connection and support. In collaboration with First-Generation Student Support Committee leadership and the marketing and communications team, a template was created. Student leaders are sent this template when elected to the chair position. The completed spotlights are featured through a variety of media platforms throughout the institution. Future plans are to expand the opportunity to participate to the broader first-generation student community and measure the effect on support community and connection. The presenters will share information on collaboration throughout an institution to develop and sustain a program and the importance of highlighting creative means to support narrative sharing in building community
MOLECULAR MECHANISMS OF NIEMANN-PICK TYPE C: INVESTIGATING GENE EXPRESSION, LIPID METABOLISM, AND MITOCHONDRIAL DYSFUNCTION IN FIBROBLASTS
Get PDFNiemann-Pick Disease Type C (NPC) is a progressive lysosomal storage disorder characterized by the accumulation of lipids, particularly cholesterol, within cells, leading to severe neurological manifestations and developmental issues. This study employs RNA-seq to compare gene expression profiles between fibroblasts derived from a healthy individual and a patient with the NPC1 mutation. A total of 12,978 genes were analyzed, revealing 191 differentially expressed genes. Functional enrichment analysis disclosed significant associations with biological processes related to development, lipid metabolism, embryonic organ development, vascularization, and neuroinflammation. Additionally, the connection between mitochondrial function and lysosomal impairment was explored, revealing that NPC1 mutant fibroblasts exhibit diminished mitochondrial volume and impaired response to nutrient fluctuations. Our findings indicate that while NPC1 mutant fibroblasts retain some ability to recover from serum starvation, their overall mitochondrial and developmental dysregulation may contribute to the pathophysiology of NPC. This study underscores the potential for targeting specific gene networks and signaling pathways to mitigate symptoms of NPC, providing a foundation for future therapeutic investigations aiming at restoring lipid homeostasis and enhancing mitochondrial function
A QUALITATIVE PROGRAM EVALUATION OF A COMMUNITY COLLEGE MENTORING AND ADVISING INITIATIVE FOR FIRST-TIME, FULL-TIME AFRICAN AMERICAN MEN
Get PDFDuane W. Reid A QUALATATIVE PROGRAM EVALUATION OF A COMMUNITY COLLEGE MENTORING AND ADVISING INITIATIVE FOR FIRST-TIME, FULL-TIME AFRICAN AMERICAN MEN 2024-2025 Monica Reid Kerrigan, Ed.D. Doctor of Education This study examines the experiences of African American male students within the Operation Achievement initiative at Unique College, a community college in New Jersey with an enrollment of over 8,000 students across its four campuses, located in both urban and suburban settings. The educational challenges faced by African American male students have been widely researched, with many studies highlighting the risk factors that hinder their academic achievement. Variables such as race and gender continue to affect the persistence, retention, and graduation rates of these students. This qualitative program evaluation evaluated Operation Achievement, an initiative designed to improve not only retention and graduation rates but also the overall experience of African American male students at Unique College. Through a series of structured interviews with current students, alumni, and staff, this research provides a deep understanding of the success of Operation Achievement at Unique College. By giving voice to the students and staff involved in Operation Achievement, this study contributes to the ongoing discourse surrounding educational achievement and equity for African American males, while offering valuable insights into the practices that have the greatest impact on student retention and success
LibKey Nomad
Get PDFLearning objectives:
● Install and set up LibKey Nomad on your own web browser.
● Understand how LibKey Nomad works and how it simplifies access to library content.
LibKey Nomad is a free browser extension provided by Rowan University Libraries that makes accessing electronic journal articles easier. It links you to open access and licensed library content and allows you to avoid publisher paywalls when on publisher websites, search engines, and Wikipedia.
Skill levels for attendees: Little to no experience
Software requirements: Non
Accelerated Tumor Growth and Lymphatic Spread of Transplantable Melanomas in Tumor Necrosis Factor(TNF)-Transgenic Mice
Get PDFMelanoma is the fifth most common cancer among American adults, with significant morbidity and mortality at 5 years remaining \u3e60% for patients with stage IV disease. The malignancy is due to the transformation of melanocytes, with one of the major risk factors being ultraviolet light exposure. Although as many as one in five human cancers have been linked to chronic inflammation, the role of inflammatory signals in melanoma growth and metastasis remains poorly understood.
Tumor necrosis factor (TNF)-transgenic (TNFtg) mice are a well-established model of chronic systemic inflammation, with involvement of joints and other organ systems. To assess the effect of TNF overexpression on melanoma in vivo, we investigated the growth of transplantable B16 melanomas (F1 and F10 sublines) in TNFtg mice (3647 strain). The B16 cell line and its derivatives originated from a spontaneous melanoma of C57BL/6 mouse. B16 cells were injected into the hind paws of TNFtg mice and non-transgenic (NT) littermates at 8-12 weeks of age. At this age, the mice have begun to exhibit early arthritis, creating a localized area of inflammation in the paw. TNFtg mice displayed highly accelerated B16 primary tumor growth compared to NT littermates (tumor area 43.7±15.2mm2 vs 15.0±15.5mm2 at week 2, p
To test whether the observed effects were linked to systemic TNF overexpression or to the localized inflamed microenvironment in the arthritic paws we also compared growth of tumors injected in the lower flank, and observed no primary tumor growth differences in this area (251±155mm3 vs 319±178mm3 tumor volume in TNFtg vs NT, p=0.3).
Finally, in order to establish whether the observed differences were specific to B16 cells or are relevant for melanoma growth more broadly, we compared growth in TNFtg vs NT mice of an independently derived melanoma line, YUMM1.1. Again, TNFtg mice showed accelerated paw melanoma growth compared to NT mice (32.6±14.0mm2 vs 19.1±20.8mm2 at week 5, p\u3c 0.01).
Overall, these results highlight a significant effect of TNF, and specifically of the TNF-driven inflammatory microenvironment, in transplantable melanoma growth in mice
Addressing Pain Management Practices and Potential Under-Medication of Women During IUD Insertion Procedures
Get PDFIntrauterine devices (IUDs) are among the most effective and safe contraceptive options available to women, yet their utilization often remains limited due in part to fear of pain, lack of adequate pain management during insertion, and absence of standardized clinical guidelines. This literature review explores current pain management strategies for IUD insertion and examines the potential under-medication of women during this procedure. Ten sources were reviewed, including randomized controlled trials, a clinical trial, linear regression analyses, and meta-analyses, with inclusion criteria focusing on pain interventions for IUD insertion in women over the past decade. Findings reveal that commonly used interventions—such as NSAIDs, misoprostol, self-administered lidocaine gel, and paracervical lidocaine injections—have not consistently demonstrated statistically significant reductions in pain. However, one randomized, double-blind, placebo-controlled trial showed that 10% lidocaine spray significantly reduced pain during tenaculum placement, uterine sounding, and IUD insertion compared to placebo. Despite advancements in pain mitigation techniques, there remains a lack of consensus on a standard of care. These findings highlight the need to establish evidence-based, standardized guidelines for pain management during IUD insertion. Doing so may reduce fear-related barriers, improve patient experience, and support broader access to this highly effective form of contraception
Tricyclic Antidepressant (TCA) Overdose Causing Diffuse Alveolar Hemorrhage: A Case Report
Get PDFTricyclic antidepressant (TCA) overdose is an uncommon complication that results from excessive administration of TCAs. Signs and symptoms include bradycardia, fever, dry mouth, and altered mental status. Patients can develop cardiac arrhythmia and diffuse alveolar hemorrhage, which can be fatal. This case report details a 65-year-old female who experienced a suspected TCA overdose as a suicide attempt. She had a history of depression and a previous suicide attempt. The patient was unresponsive with declining oxygen saturation, necessitating emergent intubation. Important lab findings included a decreased partial pressure of oxygen to fraction of inspired oxygen ratio (P/F ratio) and prolonged QRS duration on ECG. She was admitted to the ICU, where her condition worsened, leading to wide complex tachycardia, cardiac arrest, and diffuse alveolar hemorrhage confirmed by bronchoscopy. This case highlights the potential adverse effects of TCA use and raises awareness of an unusual presentation of TCA overdose
Modulation of Opioid Receptor Expression in the Ventral Tegmental Area Following Stress Exposure in Rats
Get PDFBackground: The ventral tegmental area (VTA) contains dopamine-producing neurons projecting to various brain regions. VTA dysfunction is linked to addiction and depression. Delta opioid receptor upregulation relates to chronic pain, inflammation, cancer, and early adversity. Kappa receptors in the VTA influence stress, drug-seeking, mood, and reward. Notably, chronic substance abuse upregulates the κ-receptor/dynorphin system, and the opioid system regulates social interaction needs.
Hypothesis: Stress will upregulate opioid receptors.
Methods: We compared group-housed and individually-housed rats using stress tests, analyzing behavior and quantifying VTA opioid receptor expression.
Results: Social isolation upregulated delta and kappa opioid receptors in the VTA.
Conclusions: Chronic stress increases addiction vulnerability through altered opioid receptor expression