17007 research outputs found
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Student Studying
No full textBlack and white photo of a student studying in Porter Library, behind him are shelves that are not full, possibly for periodicals.https://digitalcommons.pittstate.edu/porterbuilding/1149/thumbnail.jp
Haldeman & DeGruson
No full textBlack and white photo of Linda Haldeman and Gene DeGruson in the Haldeman-Julius room in Porter Library. They stand in front of the portrait of E. Haldeman-Julius, each holding one page of a newspaper article I will pay the postage to clear out the last of the \u27Little Blue Books\u27 at 5¢ each, c. 1960shttps://digitalcommons.pittstate.edu/porterbuilding/1158/thumbnail.jp
Porter Library
No full textBlack and white photo of Porter taken from across Cleveland St.https://digitalcommons.pittstate.edu/porterbuilding/1174/thumbnail.jp
Using Rock Bass\u27 (Ambloplites Rupestris) Diet to Explain Competition of Limited Resources Between Non Native and Native Species in the Spring River and Shoal Creek of Southeast
No full textRock bass (Ambloplites rupestris) are a nonnative species that negatively impact native species in Southeast Kansas streams due to competition of limited resources, such as food. A diet study was conducted on 26 collected rock bass to assess their impact on Kansas streams, which indirectly affects native fish. Rock bass were collected at three different sites in shoal creek: below Shermerhorn, Quapaw nation lands, and at Shermerhorn, as well as from two sites on the Spring River: Baxter Springs and below the Empire Lake. Rock bass were collected by the Pittsburg State Fisheries Management fall 2024 class using backpack electrofishing and seining. Each rock bass was dissected by the Fisheries Management class in order to see what each fish\u27s diet was composed of. Studies showed that the majority of rock bass consisted of a diet of crayfish (Orconectes) (39%), hellgrammites (Corydalus) (35%), and cactus fly larvae (Copestylum) (23%). From our studies, we can infer that nonnative species such as rock bass are competing for limited resources with imperiled native species such as Redspot Chubs (Nocomis asper)
A Novel Approach for Fabrication of Lactose Fibers Using Melt Centrifugal/Rotary Jet Spinning
No full textLactose is a naturally occurring disaccharide composed of one molecule of glucose and one molecule of galactose. It is primarily found in milk and dairy products and has various applications in the food and pharmaceutical industries.
Due to its non-toxic nature, we aimed to fabricate lactose fibers using the melt centrifugal/rotary jet spinning (MCRJS) process and assess their potential biological properties.
For this purpose, we fabricated lactose fibers and incorporated stearyl glycyrrhetinate as an active ingredient to evaluate its effects. Stearyl glycyrrhetinate, derived from licorice root, is known for its anti-inflammatory, antioxid ant, and skin-soothing properties.
The properties of stearyl glycyrrhetinate-loaded lactose fibers were assessed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), and Fourier Transform Infrared Spectroscopy (FTIR). Additionally, the biological properties of the fabricated lactose fibers were evaluated through microbial culture testing. FTIR spectroscopy confirmed chemical interactions between stearyl glycyrrhetinate and lactose molecules. The composite fibers also demonstrated antimicrobial properties, making them promising candidates for various biomedical applications, such as wound dressings, tissue scaffolds, and controlled drug release systems. These findings highlight the potential of the MCRJS process for producing biocompatible lactose-based fibers and emphasize the versatility of this technique in developing fibrous materials
Transcriptomic Analysis of EGFR and Downstream Pathway Expression in A549 and Healthy Lung Epithelium
No full textIntroduction: Clinical tests utilizing EGFR isoforms as a method of cancer screening, primarily for lung, breast, and ovarian, have been uncertain. These clinical tests lack specificity and sensitivity. We are interested in intronic single nucleotide polymorphisms (SNPs) in intronic regions. This work is an Insilco characterization and assessment of a lung adenocarcinoma cell line (A549) in association. With expression patterns of EGFR and associated pathways relative expression.
Purpose: Identify associated proteins from downstream pathways that are upregulated or downregulated in A549 compared to normal lung epithelium. Methods: The expression pipeline was applied to lung adenocarcinoma and healthy lung epithelium from publicly available cDNA short reads. This pipeline involved sequence alignment with a splice-aware aligner (STAR) and feature counting algorithm (feature Counts), and normalization, filtering and plotting with limma. Heteroscedasticity adjustment was performed with Voom.
Results/Conclusion: HRAS, FOS, JUN, and NFKB1 all are overexpressed, and TP53 is under-expressed in A549. This suggests typical cell cycle dysregulation for cancer. However, MAPK3/ERK1 suggests there is overactivity in a MAPK pathway. Under expression in SOS1 and AKT3 illicit the alternative MAPK pathways with careful attention to the JNK pathway. Also, CDH1/CDH2 differences in expression suggest that E-cadherin activity is much higher than N-cadherin activity and that they are abhorrently up and downregulated, respectively
Siloxane Modification of Thermoplastic Polyurethane Foam (TPU)
No full textHaving control over the grip or traction of a material allows for it to be applied in a variety of fields. These include sportswear, robotics, medical devices, and packaging. This project involves the modification of one specific material, thermoplastic polyurethane foam (TPU). This modification involves adding a blend of monohydroxyfunctional siloxanes into the polymer to reduce the surface energy and traction of the foam. Formulations containing 0%, 1%, 3%, and 5% siloxane will be prepared to identify the optimal balance between reduced traction and material integrity. The samples will undergo testing to determine the surface tension, composition, friction coefficient, as well as thermal and mechanical properties. These include angle goniometry to test the contact angle of a water droplet on the surface of the foam; ATR-FTIR analysis to determine the composition of the foam; Taber abrasion to for the wear of the foam; and analysis of the thermal stability and glass transition temperature of the foam. An inclined plane will be created to measure the coefficient of friction. Additional testing may be conducted according to ASTM 638 and ASTM 790 to determine the tensile and flexural properties of the foam. The anticipated outcome is to find a correlation between siloxane content and surface energy
The Effect of Mechanical Recycling on the Properties of HDPE for Commercial Applications
No full textModern plastics manufacturing methods create significant waste including sprues, runners, flash, trim, and out-of-spec parts. To reduce the carbon footprint of the plastic industry, post-industrial waste materials are often reprocessed into new parts. This investigation centered on reprocessing HDPE materials and the effects of mechanical recycling on material properties. Specifically, we focused on the degree of mechanical recycling that HDPE can undergo before a degradation in key material properties is observed. Virgin HDPE material was injection molded into test bars and subsequently reduced with a mechanical grinder. Injection molding was then repeated until the HDPE had been molded and ground ten times. Analysis was performed on virgin-, first cycle-, fifth cycle-, and tenth cycle-regrind, to determine if any degradation had occurred as a result of grinding and remolding. Reprocessed samples were analyzed for changes in thermal and mechanical properties. Degradation temperature was determined by TGA, and Crystallization temperature and melting temperature were analyzed by DSC. Melt rheology was analyzed by melt flow indexing. The tensile properties and impact strength were analyzed by tensile and Izod impact testing, respectively. Slight increases in tensile elongation were observed with an increased number of cycles. Notched impact strength and modulus decreased slightly as the number of cycles increased. Thermal stability, melt flow index, melting temperature, and temperature of crystallization were not significantly affected. Crystallinity calculated from Tm and Tc peak area determined by DSC showed no clear trend between percent crystallinity and the number of processing cycles. We demonstrated the recyclability of HDPE without significant loss of properties
Soybean Oil-Derived Acrylate/Methacrylateether for High-Resolution Additive Manufacturing
No full textThe field of additive manufacturing (AM) has seen tremendous growth in its possible applications with the introduction of multi-material 3D printing, which may be used to prototype complex structures and sophisticated geometries which improves the performance and adaptability of printed components in various sectors. Despite these developments, the broad-spectrum of materials for AM are mostly derived from petroleum oil which limits the technologies and economic viability for widespread application. In this context, vegetable oil is a renewable alternate feedstock for 3D printing due to its broad spectrum of applications, affordable price, and potential biodegradability. In this piece of work, we demonstrate the development of soybean oil-based photo-curable resins (ESBO_HEA/HEMA) for application in digital light processing vat photopolymerization. At first, epoxidized soybean oil (ESBO) was converted into acrylated/methacrylated soybean oil (ESBO_HEA/HEMA) by one-pot oxirane ring opening processas an alternative to conventional acrylated epoxidized soybean oil (AESO) generated via acrylation between ESO and acrylic acid. A series of 3D printable DLP inks have been formulated using synthesized resins (ESBO_HEA/HEMA) in the presence of photoinitiator (TPO) and or, reactive diluents (Trimethylolpropane triacrylate). Moreover, the resin\u27s viscosity of all formulated inks was investigated which are in good agreement with DLP 3D printing. Additionally, the impact of reactive diluents (TMPTA) on the thermal (DSC, TGA) and mechanical (DMA, tensile strength, and hardness) behavior of the 3D-printed object was also examined. After adding the TMPTA behavior of the materials is changed. It shows high mechanical properties, which are 4.17 MPa in ESBPO_HEA and 4.10 in ESBO_HEMA. Altogether, this work demonstrates the use of bio-based and inexpensive soybean oil which offered a simple method to prepare potential inks for DLP 3D printing that could be used in the additive manufacturing industry to make architectural models and automotive components which opens new avenues for sustainable 3D printing
Incremental Rehearsal
No full textRepetition is said to be the most important factor in learning (Symonds & Chase, 1992). A common instructional technique that also incorporates repetition is incremental rehearsal (IR), which is often implemented due to its potential efficiency and effectiveness. Previous research has indicated a positive effect on reading fluency, math intervention, and sight word acquisitions using IR teaching procedures; however, there is a stark lack of application of IR to individuals with autism spectrum disorder (ASD). Therefore, the purpose of the study was to evaluate IR as an instructional technique for skill acquisition, specifically within an early intervention setting with young children with ASD. The study used a concurrent multiple baseline design across participants to evaluate rate of skill acquisition and trials to criterion for target mastery with the implementation of IR procedures. Three participants were taught to vocally identify varied stimuli (e.g., flags, safety signs) through a modified IR procedure that used repetition and interspersed trials. Current results suggest that incremental rehearsal is an effective intervention strategy for promoting skill acquisition in children with ASD