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Antonii a Leeuwenhoek ... Epistolæ ad Societatem Regiam Anglicam, et alios illustres viros
No full textLeeuwenhoek, Antoni van. Antonii a Leeuwenhoek ... Epistolæ ad Societatem Regiam Anglicam, et alios illustres viros. Leiden, 1719
Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/alfred-cohn-collection/1007/thumbnail.jp
Myographia nova. Illustration. Details
No full textOne of the illustration from Myographia nova: or, a graphical description of all the muscles in the human body, as they arise in dissection. Details
Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/alfred-cohn-collection/1013/thumbnail.jp
Isaac Newton. The mathematical principles of natural philosophy
No full textNewton, Isaac. The mathematical principles of natural philosophy
Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/alfred-cohn-collection/1020/thumbnail.jp
Portrait of Louis Pasteur
No full textLouis Pasteur (1822 - 1895), French biologist, microbiologist, and chemist, by Albert Edelfelthttps://digitalcommons.rockefeller.edu/alfred-cohn-collection/1047/thumbnail.jp
The house where Louis Pasteur was born
No full textThe house where Louis Pasteur was born. Dole, Francehttps://digitalcommons.rockefeller.edu/alfred-cohn-collection/1046/thumbnail.jp
Waltersdorf’s church
No full textWaltersdorf’s church, circa 1937https://digitalcommons.rockefeller.edu/blobel-molecular-biology/1002/thumbnail.jp
Günter Blobel in Lech, Austria
No full textLech, Austria, ca. 1974
Left to right: Reiner, Reiner’s first wife, Renate, Peggy, Hans’ wife, Günter, Laura, Günter’s wife, and Hans, the oldest of the Blobel brothers
Courtesy of the Blobel family
Günter finished school in 1954 but as a member of the “capitalist” classes was barred from studying at a university in East Germany. Fortunately, travel to West Germany was not yet a problem, so he studied medicine in Frankfurt and then in Kiel, München and Tübingen, graduating in 1960 from the University of Tübingenhttps://digitalcommons.rockefeller.edu/blobel-molecular-biology/1009/thumbnail.jp
McArdle Laboratory for Cancer Research
No full textMcArdle Laboratory for Cancer Research, circa 1940s
The McArdle Laboratory for Cancer Research was established in 1940 as one of the first basic cancer research facilities in the world.https://digitalcommons.rockefeller.edu/blobel-molecular-biology/1014/thumbnail.jp
Signal hyposesis. Illustration
No full textThe signal hypothesis for secretory proteins formulated by Günter Blobel and David Sabatini.
Blobel and Sabatini hypothesized in 1971 that a nascent peptide, bearing a terminal ‘signal’, interacts with a binding factor attached to the endoplasmic reticulum (ER) membrane, allowing docking of the ribosome and its associated mRNA. Upon passage of the newly synthesized protein across the ER membrane, the ribosome is able to dissociate from the site of synthesis and re-enter the cytoplasmic pool, ready for another round of synthesis. From Blobel, G. and Sabatini, D. (1971) in Biomembranes, pp.193-195, Plenum Press, New Yorkhttps://digitalcommons.rockefeller.edu/blobel-molecular-biology/1024/thumbnail.jp
Günter Blobel: Stockholm and beyond
No full textGünter Blobel was awarded the Nobel Prize in Physiology or Medicine in 1999 for “the discovery that proteins have intrinsic signals that govern their transport and localization in the cell.” These signals have been shown to be universal in living cells. The techniques Blobel developed to study translocation are now used in laboratories around the world. Beyond resolving a basic biological problem, Blobel\u27s research has furthered scientific understanding of human physiology and pathology. His seminal work laid the foundation for the modern field of molecular biology, and generations of scientists have built on his findings.
Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/blobel-molecular-biology/1036/thumbnail.jp