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    The Rockefeller Institute Faculty and Students Club price list

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    The Rockefeller Institute Faculty and Students Club price list, 1964-65 Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/the-evolving-campus/1066/thumbnail.jp

    The Rockefeller Institute: 1901-1929

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    In the spring of 1897, Frederick T. Gates was on vacation in the Catskills when he read a book titled Principles and Practice of Medicine. The book, by Sir William Osler, was to have a profound influence on Gates, who had become the philanthropic advisor to John D. Rockefeller, Sr., in 1981. From his observations at sickbeds and his conversations with physicians, Gates had become skeptical about the current state of medicine. At the turn of the century, the toll taken by infectious disease in the United States was a sobering statistic. The thousand-page Osler survey confirmed Gate\u27s skepticism, but it also made him aware of the potential of scientific investigation for solving the mysteries of disease. ...it seemed to me, Gates later wrote, an institute of medical research ought to be established in the United States. And here was an opportunity for Mr. Rockefeller to do an immense service to his country and perhaps the world. When Gates sent his memorandum to Rockefeller, the industrialist was in the process of withdrawing from the active management of the Standard Oil Companies. Although he was preoccupied, Rockefeller did not ignore the memorandum. In January 1901, Rockefeller, Sr., agreed to establish the institute. Not long afterward, on June 14, 1901, the Rockefeller Institute for Medical Research was incorporated, and a charter was adopted stating, The purpose of the corporation is medical research with special reference to the prevention and treatment of disease. ( From Institute to University: A historical sketch of The Rockefeller University, 1983)https://digitalcommons.rockefeller.edu/the-evolving-campus/1000/thumbnail.jp

    Antique porcelain mortar and pestle

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    Antique porcelain mortar and pestle, Haldenwanger Berlin Courtesy of the Rockefeller Hospital Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/the-evolving-campus/1006/thumbnail.jp

    First keys

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    First keys, circa 1900s Courtesy of Jeff Prout Photo by Lubosh Stepanekhttps://digitalcommons.rockefeller.edu/the-evolving-campus/1009/thumbnail.jp

    River Campus Opening Celebration

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    River Campus opening celebration, May 2019 Photo by Mario Morgadohttps://digitalcommons.rockefeller.edu/river_campus/1081/thumbnail.jp

    Haochen Zhang, Piano

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    2019, March 15 Haochen Zhang, piano, performed Leoš Janáček: In the Mists; Claude Debussy: Images, Book II (L111); Pierre Boulez: Piano Sonata No.1; Franz Liszt: Piano Sonata in B-Minor.https://digitalcommons.rockefeller.edu/tri-institutional-noon-recitals/1037/thumbnail.jp

    Audrey Vardanega, Piano

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    2019, March 22 Audrey Vardanega, piano, performed Brahms: 3 Intermezzi, Op. 117; Beethoven: Piano Sonata No. 26 in E-flat Major, Op. 81A (“Les Adieus”); Debussy: Selections from Piano Preludes Book II – Brouillards; La Peurta del Vino: Mouvement de Habanera; Beethoven: Piano Sonata No. 28 in A Major, Op. 101https://digitalcommons.rockefeller.edu/tri-institutional-noon-recitals/1036/thumbnail.jp

    From Face Perception to Individual Recognition: The Missing Link

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    Recognizing other individuals is a key social aspect of our everyday lives. To recognize a familiar individual, we must establish a link between sensory inputs and a representation of that individual held in memory. In primates, faces play a particularly important role on the sensory side of this process, which is reflected in an extensive network of face-selective areas along the inferior temporal lobe. However, where and how memory is re-activated during face perception remains unclear. Using functional magnetic resonance imaging (fMRI), we measured whole brain activity in macaques while they were watching pictures of other monkey faces that were either long-term acquaintances, visually familiar, or totally unfamiliar. In comparison to unfamiliar faces, the entire face-processing network showed increased activity in response to familiar faces of long-time personal acquaintances. In contrast, faces that were only visually familiar elicited less activity than totally unfamiliar faces in most face-selective areas. The face-processing network thus distinguished personally familiar faces from visually familiar faces. Personally familiar faces also prompted the activation of two previously unknown face-selective areas in the temporal lobe. One area was located in the perirhinal cortex (PR), which has been associated with declarative memory, and the other area was embedded in the temporal pole (TP), a region previously associated with social knowledge. These two novel face areas showed a non-linear response as blurred faces became gradually visible, rapidly becoming active when the faces of personal acquaintances became recognizable. Thus, mimicking the perception of a face approaching us, this paradigm revealed a neural correlate of the \u27aha!\u27 recognition moment in face areas TP and PR. As a first step towards advancing our understanding of the neuronal processing of individual recognition, our fMRI experiments identified two novel face areas specifically involved in recognizing familiar faces. However, the hemodynamic response cannot directly assess neurophysiological properties. Using fMRI-guided electrophysiology, we investigated the responses of neurons within the novel face area TP in awake monkeys, and we provided the first systematic evidence of cells selective for familiar faces. A high fraction of neurons in face area TP were selective for familiar monkey faces, and unfamiliar faces that were physically similar failed to elicit the same neural responses. Importantly, neurons in face area AM, which is thought to compute facial identity at the top of the face perception hierarchy, were not modulated by familiarity. Within TP, neurons also responded to monkey bodies, and to monkey vocalizations. Maximum activity was elicited by the joint observation of faces and bodies, and audiovisual interactions were evident in some TP neurons. Together, these results reveal neuronal processes underlying memory re-activation during face perception and generate hypotheses for testing how individual recognition is achieved through different modalities, thus advancing our understanding into how unique representations of familiar individuals are developed at the neural level

    Historic Laboratory. View no.14, January 2019

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    Bench in the historic laboratory, detail. Flexner Hall, 1st floor, 2019 Photo by Zach Veilleuxhttps://digitalcommons.rockefeller.edu/historic-laboratory/1027/thumbnail.jp

    Geoffrey Montgomery: Discovering That Genes Are Made of DNA

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    In celebration of the 75th anniversary of the Avery-MacLeod-McCarty landmark paper: Discovering that genes are made of DNA Talk by Geoffrey Montgomery Posted with permissionhttps://digitalcommons.rockefeller.edu/dna-talk-montgomery/1000/thumbnail.jp

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