13468 research outputs found
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Final Scholarly Project: Enhanced Recovery After Surgery (ERAS) Guidelines for Pancreaticoduodenectomies
Full text linkA pancreaticoduodenectomy, or Whipple procedure, is the only curative option for pancreatic cancer. For those eligible for tumor resection, the Whipple procedure is a difficult surgery for both the patient and provider. Complications following pancreaticoduodenectomy are numerous and include infection, delayed gastric emptying, high hospital costs, and pancreatic fistulas. Enhanced Recovery After Surgery (ERAS) protocols exist to provide evidence supporting standardization of practices that lead to the improvement of these patient outcomes. An ERAS protocol for the pancreaticoduodenectomy, first established in 2012, is inconsistently implemented in healthcare facilities. Researchers collected data involving the use of the Whipple procedure ERAS guidelines in improving the following three outcomes: length of stay, incidence of incisional infection, and rates of delayed gastric emptying. After receiving approval from hospital administration, the project team will gather data from previous patients and educate staff members regarding the upcoming clinical practice change. A trial implementation period will last one year, or until 50 patients are enrolled. Following proper ERAS execution, investigators will again collect data and compare results in the three chosen outcomes. The project team expects that implementation will demonstrate an improved incidence rate of infection, delayed gastric emptying, and shorter length of stay following the pancreaticoduodenectomy. If the desired results are not realized, additional research will be necessary to investigate causative factors and ways to improve current practice
Urinetown: The Musical
No full texthttps://digitalcommons.otterbein.edu/theatre_dance_gallery/5919/thumbnail.jp
Urinetown: The Musical
No full texthttps://digitalcommons.otterbein.edu/theatre_dance_gallery/5918/thumbnail.jp
Dames at Sea
No full texthttps://digitalcommons.otterbein.edu/theatre_dance_gallery/5902/thumbnail.jp
Dames at Sea
No full texthttps://digitalcommons.otterbein.edu/theatre_dance_gallery/5895/thumbnail.jp
Characterization of RmdA and RmdB in Cyclic-di-GMP Signaling of Streptomyces coelicolor
No full textStreptomyces coelicolor is a soil bacterium known for its antibiotic production. It utilizes cyclic-di-GMP (c-di-GMP) signaling to regulate important cellular processes like cell cycle progression and antibiotic production. Our research focuses on the specific roles of two key proteins, RmdA and RmdB, in managing c-di-GMP levels, and aims to uncover the specific roles and functions of these proteins. Preliminary data from our lab suggest that RmdB may form dimers, which is important for understanding how c-di-GMP signaling is regulated in Streptomyces coelicolor.
To further investigate, our study uses various methods to examine the impact of RmdA and RmdB on bacterial growth and behavior. These include using different media plates to assess how each protein affects bacterial growth, antibiotic resistance assays to uncover possible differences in sensitivity, and interspecies plating to analyze how Streptomyces coelicolor interacts with other bacterial species. By comparing the effects of RmdA and RmdB under these experimental conditions, we aim to deepen our understanding of how these proteins regulate c-di-GMP signaling and their individual contributions to bacterial processes.
This research could provide valuable insights into bacterial signaling mechanisms and contribute to our understanding of how c-di-GMP influences processes like antibiotic production in Streptomyces. Additionally, it may offer new perspectives on how these proteins can be targeted in future medical applications, such as developing novel antibiotics or controlling bacterial behavior
2025 Otterbein University Commencement Program
Full text linkProgram for the 2025 Otterbein University Commencement Ceremonies.https://digitalcommons.otterbein.edu/commencement/1018/thumbnail.jp
Rot Collection: Psalms of Loss
Full text linkThis project is a multidisciplinary approach to understanding humanity’s role in maintaining Nature’s existence. Drawing on works of ecophilosophy and psychoanalysis, I propose a new theory—the theory of the enunciated Other—that seeks to explain humanity’s inborn tendency to destroy Nature and provides a potential framework to restore—nay instaure— Nature in a different way. This collection of poetry and illustrations serves as my attempt to restore Nature through verse—to give the natural world a novel existence through line and lyric
A Proposal: Gap Analysis on Novice Advanced Practice Provider Role Transition within the Inpatient Setting
Full text linkBackground: Healthcare specialties are an integral part of patient care yet are briefly discussed throughout the academic journey of the advanced practice provider (APP). Hiring departments or facilities must provide further education on complex specialties. Due to a decline in practicing physicians, APPs will provide more patient care within specialties by 2032.
Purpose: To emphasize the importance of a high-quality onboarding program for the success of the APP, the department, and the hiring facility.
Method: Proposed data collection involves a two-part survey using the Novice Nurse Practitioner Role Transition (NNPRT) scale and an onboarding experiences survey.
Results: A literature thematic analysis indicates a structured onboarding program enhances employee retention, improves knowledge, increases satisfaction, and positively impacts the APPs confidence level. Descriptive statistics from the survey results will be compared to the thematic analysis to identify gaps within inpatient onboarding programs and the current role transition experience.
Conclusion: Research highlights the significance of a high-quality onboarding program and the advantages structured programs offer APPs, departments, and hiring facilities. Despite known benefits, many onboarding and orientation programs still need more structure, which can impede the transition into new roles. Addressing gaps within onboarding programs is crucial with the exponential growth of APPs and the decline in physicians
ROSEATE TERN (STERNA DOUGALLII DOUGALLII) NEST SHELTER APPLICATIONS
No full textRestoration projects for endangered species like the Roseate Tern (Sterna dougallii) often rely on experimental management and research to aid reproductive success. A common practice on islands in the Gulf of Maine is to construct several rock and wood nest shelters to encourage breeding Roseate Terns to nest and raise young; however, there is limited research on what preferences and effects, if any, differing characteristics of these shelters have on their productivity. This study investigated cardinal orientation specifically, taking place on Audubon Seabird Institute’s Stratton Island (43.5051° N, 70.3117° W) during the summer of 2025 (May 13th – August 7th). Roughly 80 rock shelters were constructed, with 20 marked for the study, delegating 5 shelters to each cardinal direction, although all active shelters during the A-wave were categorized and analyzed for the study. Factors such as clutch size, hatch date, the number of chicks per nest, B-chick weight, and chick outcome for each nest were measured in relation to each nest’s orientation. All chicks were banded, and only B-chicks were weighed on days 0, 1, 2, and 3 (under proper permits designated by the Audubon Seabird Institute) to determine their success. Chick outcome was categorized as “likely fledged,” “likely died,” “indeterminate,” and “dead.” The only productivity factor of statistical significance was the weight of B-chicks on day 3 of their life, but this was likely due to a sampling inconsistency. This study found that orientation had little to no effect on various productivity factors, but a selection preference was shown for orientation, with the majority of Roseate Terns selecting West-facing shelters (58%), some selecting North-facing shelters (21%), and few (mostly B-wave birds) selecting east- and south-facing shelters (11%), with the remaining birds nesting in natural structures (10%)