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NeuN Immunoreactivity in Olfactory Epithelium and Telencephalon Across Development of Axolotls
No full textNeuN, or Neuronal Nuclei, is a protein commonly used as a biomarker of neuron maturation, however, recent findings within the lab have found that expression of anti-NeuN varies, occurring only in select regions, and not always indicating neuron maturation. We have found cytoplasmic and some nuclear NeuN expression in the olfactory epithelium and olfactory bulb. The olfactory region is a highly compelling target as it is the only location within humans that neuron proliferation continues beyond early development. Continuations of this research will investigate NeuN expression throughout the maturation process of axolotls and further elucidate the expression of NeuN
Determining the Locations of Solar Farms and Why That is Essential
No full textIt can be troublesome to find the right spot for a solar power farm. As our population grows, the need for clean and sustainable energy becomes more and more prevalent. On top of the need for space these installations often require, these farms need to be in a place that is easy to access, while also not being intrusive to both the local landscape, the environment, and local perception. Therefore, we require a consistent and efficient way to identify the proper sites for Solar Photovoltaic Farms. Several studies have created categorization techniques and calculations that can be used to identify the best places for an installation. These operations consider space, access to sun, and other factors to ensure the best space is identified. Additionally, other studies have shown that it is possible to land share with both conservation sites and agricultural farms. The presence of these panels neither affects these areas positively or negatively, while also providing another source of income and energy for landowners. Combining the algorithms with land sharing, it will be more than possible to find the space we need to keep up with energy demands
Roo
No full textPictured is Grace Lynch petting a kangaroo as he sticks his tongue out for the camera in a wildlife park in Sydney, Australia.
Submitted as part of the Spring 2025 Study Abroad Photo Contest.https://digitalcommons.ursinus.edu/study_abroad_photos/1036/thumbnail.jp
Everything But Wrestling: How Women Wrestlers Perform Dominance
Full text linkWomen’s wrestling continues to grow at the high school level, with more young girls joining the sport each year. Yet, as more women join wrestling, a heavily masculine sport, questions about gender preintimation on women’s teams arise. This study asks three questions about the role of gender on women’s teams: 1) Does an individual’s gender identity, in a heavily gendered sport like wrestling, factor into the development of team culture? 2) What, if any, forms of gendered socialization emerge as women enter wrestling? 3) In what way are women socialized because of their gender? Data was gathered via interviews, in which female and male wrestlers from club and varsity teams were repeatedly interviewed. Participants were asked about their experiences in wrestling, their self-perception as athletes, and their difficulties during their wrestling careers. The results indicate that varsity women use misogynistic jokes and male coded language to display their masculinity. In doing so, the varsity women perform dominance which is the basis of wrestling
Computational Analysis of Proton Conductivity Factors in Grotthuss-style Mechanisms
Full text linkThe mechanism and fundamental molecular properties involved in proton conduction are discussed. Four calculable properties are presented: the proton affinity, binding energy (between protonated and neutral forms), intramolecular tautomerization barrier, and proton hopping barrier. An overview of the computational methods used in this thesis, including an introduction to the many-body Schrödinger equation and Density Functional Theory, as well as a look at Plane-Wave Density Functional Theory and Gaussian-Type Orbital Density Functional Theory are presented. 4,5-dimethyl-[1,2,3]-triazole is used as a model system, with 10 variations being generated with varying amounts and positions of fluorine substitution on the methyl groups. Preliminary calculations of proton affinities and tautomerization barriers were completed using Density Function Theory, and the results discussed, as well as comparisons of calculated properties in plain [1,2,3]-triazole to experimentally determined activation energies for proton conduction. It was determined that in the orthorhombic crystal phase of [1,2,3]-triazole that the barrier to intramolecular tautomerization is likely the highest-energy barrier, and calculated results are shown to match closely with experimental data. In the liquid phase of [1,2,3]-triazole, the proton hopping barrier was shown to be the most likely highest-energy barrier, with calculated results closely matching experimental data. The currently available calculations of the proton hopping barriers are discussed, and future directions are established. In addition, the implications of binding energies on the distribution of conformers in a liquid phase are discussed, and a map of eight identified conformers of 4,5-dimethyl-[1,2,3]-triazole and 4,5-dimethyl-[1,2,3]-triazolium with their relative binding energies are presented and discussed. The results presented provide insight into the decisions made during the design of novel proton conducting materials, and promise to improve our understanding of proton conduction
Nothing About Us Without Us : State-Level Disability Accommodation in the Wake of the ADA
Full text linkThe Americans with Disabilities Act (ADA) was passed in 1990 and protects people with disabilities (PWDs) from discrimination and includes provisions to make society more accommodating. The issue is that the ADA is federal legislation, but most of the implementation occurs at the state-level which means that some states are more accommodating than others. This project attempts to answer the following question: What factors contribute to the discrepancies in state-level disability policy and accommodation? It includes a quantitative study of all 50 states and investigates the impact of state income per capita, state partisanship, and business and disability interest group strength to understand the difference in state-level disability policy. There is also a comprehensive case study on Maryland to analyze entities like the governor, attorneys general, and specific interest groups that may make a state more accommodating than others. Both state partisanship and business interest groups significantly influence state-level accommodation suggesting actors at the state-level can enforce, implement, or change policies. Broader implications demonstrate that politics, partisanship and interest groups matter, and that states have a greater impact on disability policy, and policy in general, than previously reported
Live Art
No full textThis is a photo of a beautifully placed window in an art museum in Merida, Mexico that makes the view look like the paintings on the wall.
Submitted as part of the Spring 2025 Study Abroad Photo Contest.https://digitalcommons.ursinus.edu/study_abroad_photos/1059/thumbnail.jp
Food & Drugs Unite: Targeting Leukemia with a [6]-Gingerol and 5-Fluorouracil Combination Chemotherapy
No full textLeukemia is a cancer found in the blood characterized by rapid growth of blood cells. This study examines the effect of [6]-Gingerol and 5- Fluorouracil (5-FU) on the proliferation of the Jurkat cell line, a cell line that is a model for T-cell leukemia due to similar mechanisms. MTT assay technique was used to measure cell proliferation and viability. We expected to see high cell fractional affect and reduced proliferation as the concentrations of the combinational therapy of [6]-Gingerol and 5-FU increased. These two cell compounds were selected because of their anti-carcinogenic effects: [6]-Gingerol is used aid in the inflammation of cancer and 5-FU initiates apoptosis on cancer cell because cancers often thrive in inflamed environments. To complete our overall project, we will need to run more trials with different concentrations of the cell compounds
Analyzing CIE Texts Through History Using R
No full textIn this presentation, we analyzed three separate CIE texts from different time periods. First, “The Allegory of the Cave” from 380 BC, then “The Declaration of Independence” from 1776, and lastly “The Lottery” from 1948. We compared them using tidy text techniques like sentiment lexicons, creating word clouds, and bigram analysis to see if the types of words and sentiments used have changed over time in these short texts
Sex Differences in Anxiety and Locomotion After Cervical Spinal Cord Injury
No full textGlobally, more than 15 million people are living with spinal cord injuries (SCI) . Despite these great harms, research has yet to discover a cure. The Perlmutter lab is developing an electrical spinal stimulation protocol, with preliminary findings revealing that stimulation has a significantly greater motor impact on female rodents. Recent findings have identified possible sex differences in SCI recovery, with several studies finding increased recovery in females . We sought to investigate sex differences in recovery using behavioral assays such as the open-field test (OFT) and light-dark box (LDB) as part of an ongoing study exploring effects on recovery of emotional factors, such as chronic pain, depression, and anxiety