16812 research outputs found
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Biophysical Characterizations and Applications of DNA-Lipid Micelles
No full textDNA–lipid conjugates are amphiphilic molecules where a lipid is covalently attached to DNA, enabling applications that leverage both DNA programmability and lipid micelle self-assembly. This work describes two independent but conceptually linked projects using DNA–lipid conjugates for drug delivery and chemical synthesis. In the first project, DNA–lipid conjugate micelles are explored for drug delivery to resolve the instability of lipid micelles upon dilution or interaction with serum proteins like albumin. DNA–lipid conjugates synthesized by solid-phase chemistry self-assemble into micelles whose stability is enhanced through DNA-DNA interactions, such as G-quadruplex or duplex formation. The second project explores DNA–lipid conjugates as catalysts for enantioselective organic synthesis, where the lipid promotes reagent– DNA interactions and the DNA serve as a chiral scaffold for a metal catalyst. Complexation of a copper–bipyridyl catalyst with the DNA scaffold and successful catalysis of a Michael addition demonstrate the feasibility of this micellar DNA-based catalytic system as a potential alternative to traditional organic solvent-dependent synthesis
Ursinus Colloquium on Liberal Education: Liberal Arts on Offense
No full textThis program for Ursinus College\u27s third Colloquium on Liberal Education lists the speakers, panel discussions and activities of the two-day event. It includes alumni reflections on the value of a liberal education and provides introductory remarks about the relationship between liberal education and pre-professional education.https://digitalcommons.ursinus.edu/cole/1003/thumbnail.jp
2025-2026 Ursinus College Course Catalogue
No full textA digital copy of the 2025-2026 Ursinus College Catalog. It contains details of the curriculum, departmental requirements and courses of instruction as well as the Open Questions core requirements, experiential learning and the Common Intellectual Experience (CIE). Academic policies, special opportunities and scholarships, off-campus programs and graduation requirements are also outlined.https://digitalcommons.ursinus.edu/uccatalog/1112/thumbnail.jp
Causes of Voter Wait Times During the 2022 U.S. Midterm Elections
Get PDFVoter wait times have been an enduring issue in American Elections, with significant variation across individuals, voting precincts, and states. Past research has found that waiting in lines at the polls negatively impacts future voter turnout and public confidence in voting institutions. Additionally, a racial gap in voter wait times and resource allocation has been found in numerous studies that implies serious issues with the equality of our elections. The exact causes of the racial gap and voter wait times in general are still somewhat unclear, but prior work has considered as causes the allocation of voting resources, the procedural aspects of voting, as well as other non-structural issues. This study investigates the causes of voter wait times, with a specific focus on the role of wealth versus racial make-up of districts. Using several regression analyses on a combined dataset from the CCES, SPAE, and the U.S. Census, I examine the role of different causes of voter wait times in the 2022 midterm elections. To better understand how resource allocation is determined, I conducted a qualitative interview with a Philadelphia election official to identify how unequal allocation could occur. My findings suggest that community wealth is not a significant driver of voter wait times, but that racial gaps in wait times persist at the individual and local level. My findings also show that a racial voter wait gap exists in a number of states, and that differing laws or other factors at the state level either cause or contribute to the gap. Ultimately, this means that other factors must cause the racial voter wait time gap, including institutions and how resource allocation is determined
The Grizzly, March 6, 2025
Get PDFBears\u27 Basketball Season Comes to an End • Tidbits About Title IX • Bears Together Strong • Saher on the Modern Rainbow Scare • Fundamentals • Opinions: Ranking Dining Options on Campus • Gymnastics Looks to Finish Strong! • Women\u27s Wrestling Ready to Rumblehttps://digitalcommons.ursinus.edu/grizzlynews/2049/thumbnail.jp
American Story
No full textThis book stack was created by a first-year student at Ursinus College participating in a Common Intellectual Experience event. After a group Stacks on Stacks activity in Fall 2024, students were invited to submit their own individual creations in Spring 2025.https://digitalcommons.ursinus.edu/cie_stacks/1053/thumbnail.jp
A Life\u27s Journey
No full textThis book stack was created by a first-year student at Ursinus College participating in a Common Intellectual Experience event. After a group Stacks on Stacks activity in Fall 2024, students were invited to submit their own individual creations in Spring 2025.https://digitalcommons.ursinus.edu/cie_stacks/1070/thumbnail.jp
Untitled Book Stack
No full textThis book stack was created by a first-year student at Ursinus College participating in a Common Intellectual Experience event. After a group Stacks on Stacks activity in Fall 2024, students were invited to submit their own individual creations in Spring 2025.https://digitalcommons.ursinus.edu/cie_stacks/1071/thumbnail.jp
Untitled Book Stack
No full textThis book stack was created by a first-year student at Ursinus College participating in a Common Intellectual Experience event. After a group Stacks on Stacks activity in Fall 2024, students were invited to submit their own individual creations in Spring 2025.https://digitalcommons.ursinus.edu/cie_stacks/1091/thumbnail.jp
The Historical Enemy
No full textThis book stack was created by a first-year student at Ursinus College participating in a Common Intellectual Experience event. After a group Stacks on Stacks activity in Fall 2024, students were invited to submit their own individual creations in Spring 2025.https://digitalcommons.ursinus.edu/cie_stacks/1093/thumbnail.jp