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Antibiotics and Cellular Proliferation in Infected Burn wounds
No full textResearch will be conducted on the effect of antibiotics used to treat a S. aureus-caused infection on the rate of cellular proliferation in Burn Wounds. A burn wound that compromises the skin barrier allows for pathogens to enter and triggers the body’s immunosuppression response. This response inhibits or completely prevents the immune system of an individual from resisting any pathogens that may enter the body, causing the incidence of infection in burn victims to be high. The antibiotics used to treat these infections have been found to affect the proliferation rate of stem cells when used to isolate a cell culture. In burn victims, wound healing time is especially important to quickly cover the open and compromised skin barrier, to prevent other infections. If, due to the antibiotics used to treat a primary infection, the wound takes more time to heal, a secondary infection is more likely. Unlike other studies, this study will use the antibiotics as the independent variable and will use earthworms to simulate burns using hot metal, and make a connection between these burns in earthworms to burns in humans. By testing the proliferation rate of the via samples taken from the worms in the antibiotics and with Staphylococcus aureus, it is possible to find if antibiotics affect the wound healing time in burn victims with Staphylococcus aureus
Dissecting Distant Galaxies Using Normalized High-Redshift Quasar Spectra
No full textQuasar-absorber systems are integral to the study of distant objects that are too dim to be observed on their own. These objects, distant in both space and time, tell us the story of the early universe, including the evolution of galaxies. Using quasars as backlights, we can analyze the composition of faraway galaxies via their spectra. This project analyzed spectra taken by the VLT in Chile by normalizing them in the program Linetools. This required the calculation of both the quasar and the galaxy’s redshifts, as well as the manual fitting of the continuum. Once the spectrum was normalized, effectively removing the quasar’s emission lines, the absorption lines of the galaxy were measured using equivalent width and column density. These measurements were used to calculate metallicity, which revealed that the galaxy is very young due to its low quantity of metals. However, the presence of FeII indicated Type II supernovas, proving that it has existed through the lifetimes of some stars within it. Both the redshift and the presence of highly ionized metals indicated that the galaxy is very near the quasar. Ultimately, this galaxy is a piece in the much larger puzzle that is the study of quasar-absorber systems, and each analysis of such a system brings us one step closer to revealing the greater picture of the evolution of the universe around us
An Opportunity To Help\u27
Get PDFCampaign co-chairs Robert Hill \u2783 and Margaret Platt Hill \u2783 stress the importance of giving back
Power Their Promise
Get PDFWe all want to leave the world better than we found it. Here\u27s one way to do it
The New Ball Coach
Get PDFAfter a two-decade climb, Billy Napier \u2703 reached the top of the college football mountain in 2021, when he was named head coach at the University of Florida
The Race To Reduce
Get PDFClimate change threatens our health and hopes for the future. Here is what Furman is doing about it
The driving effects of common atmospheric molecules for formation of clusters: the case of sulfuric acid, formic acid, hydrochloric acid, ammonia, and dimethylamine
No full textOne of the main sources of uncertainty for understanding global warming is understanding the formation of larger secondary aerosols. The beginning stages start with the formation of prenucleation complexes from precursor monomers of acids, bases, and organic molecules. The detailed interactions responsible for prenucleation and subsequent aerosol formation are difficult to decipher experimentally. We present a computational chemistry study of the interactions between three different acid molecules and two different bases. By combining a comprehensive search routine covering many thousands of configurations at the semiempirical level with high level quantum chemical calculations of approximately 1000 clusters for every possible combination of clusters containing a sulfuric acid molecule, a formic acid molecule, a hydrochloric acid molecule, an ammonia molecule, a dimethylamine molecule, and 0–3 water molecules, we have completed an exhaustive search of the DLPNO-CCSD(T)/CBS//ωB97X-D/6-31++G** Gibbs free energy surface for this system. This first detailed study of HCl interacting with two other acids and two bases reveals the subtleties that exist in the formation of prenucleation complexes for this system. We find that nitric acid forms stronger interactions in dry clusters than hydrochloric acid does. Often as the clusters grow larger with hydration, the sequential energies of clusters containing hydrochloric acid become more favorable than those with nitric acid. The detailed geometries of each minimum free energy cluster are often more important than traditional acid or base strength, which makes a priori prediction of which atmospheric species will be most important for driving prenucleation growth quite difficult. The results presented in this paper add to the conclusions that hydrogen bond topology and the detailed structural interactions that are subtle interplays between enthalpy and entropy are as important as conventional ideas such as acid/base strength