10368 research outputs found
Sort by
Shelf Life
Get PDFAn examination of eulogies, a charmer and humorist\u27s asides, the ABCs of neuroscience for young children, a deadly engagement party and Greenville histor
The Novel Advancement of An Opioid Antagonist Used to Treat Dissociation in DID
No full textDissociative Identity Disorder (DID) is a disorder caused by extreme trauma. When someone is young and goes through abuse, the brain of an individual that develops DID doesn’t know how to process the trauma, so it creates one or more identities to hold the traumatic memories. These identities alternate based on life experiences, stress, and trauma. DID and alternation of identities is often accompanied by dissociation and derealization. Activation of the Kappa opioid receptor (KOR) has been found to induce dissociation, and the KOR is implicated in dissociative disorders. KOR antagonists can thus be used to help with dissociative symptoms. JDTic is a long lasting opioid antagonist primarily for the KOR. Using the Schrodinger Maestro software, I docked this antagonist using the GLIDE ligand docking module. I was able to decrease the docking score of a JDTic derivative by 3.14 kcal/mol through removing repulsive interactions and increasing the hydrophilicity of certain regions of the molecule. Since this was only determined through computational methods, these modifications would need to be tested before use. If it passes the testing, hopefully JDTic will be used to help those with DID and other dissociation and derealization disorders
Development of a Superhydrophobic Oleophilic Motorized Polypropylene Skimmer-Boom Collector Oil Tanker Attachment to Decrease Oil Spill Dispersion
No full textToday, the impacts of oil spills have become more severe due to an increasing population that creates an increasing oil demand. Current oil spill recovery methods such as skimmers and oil booms only have a 10-30% recovery rate during a successful cleanup. Thus, there needs to be an improvement in current recovery methods because oil spills do occur and the recovery process needs to be perfected. The purpose of this research was to create a prototype device capable of collecting at least 25% of all oil during experimentation and combining modern recovery methods with oleophilic (oil-absorbent) material. The device was created by 3D printing a coil wrapped with polypropylene strips which act as an oleophilic substance with an additional layer of hydrophobic spray. The coil was attached to a ball and socket joint primarily controlled by a motor that moved the device left and right within a simulated saltwater environment and used engine oil to represent a spill. The results showed that the device was able to collect an average of 13.3 mL of oil, which is about 8.87% of all total oil. A Chi-Square goodness of fit test concluded that the null hypothesis was rejected since the ��2 value was 94.850, greater than the critical value of 16.919. The engineering goal was not met, but the device can be improved using a fourbar linkage would help improve the stability of the design since it uses two pivots and a bar instead of relying on supports
Evaluating the Efficiency of Application Methods for Microbe-Based Formulations on Reducing Glyphosate Levels in Soil
No full textGlyphosate, one of the most prominent herbicides globally, produces a harmful byproduct (aminomethylphosphonic acid) (Carretta et al., 2022), with glyphosate contamination beginning to form concerns for ecosystems and human health (Botten et al., 2021). The purpose of this study was to determine the most effective method of bioremediating glyphosate using three microbe applications (liquid, granules, and powder) in two moisture levels (40 and 80 mL). It was hypothesized that of the microbe formulations, the liquid form would perform the best in the 40 mL of water and the granular form would perform best in 80 mL of water (due to the fact that the granules would absorb the excess water in the environment to make contact with the glyphosate for remediation). PVC pipes were layered on small-pore filters, mesh, and containers to collect the leachate. The columns were filled with soil, glyphosate, water, and three microbe applications, then a spectrophotometer was used to measure glyphosate absorbance at 570 nm. The results concluded that the liquid formulation was the most suitable for both water environments as shown by a Two-Way ANOVA test and a Tukey HSD. The results indicated a significance for water level, F(1, 232) = 6.24 , p = 0.013, as well as significance for microbe application method, F(3, 232) = 345.38, p = \u3c0.001, and interactions between water level and microbe applications, F(3, 232) = 3.80, p = 0.011. This suggests that in future works, liquid formulations should be considered for bioremediation of glyphosate in soil
Drop Stop
No full textDropping items out of a tree stand is a problem that all hunters will face. Our research from Deer and Deer Hunting said that 1 in 3 hunters fall out of their stand due to reaching for falling gear. One common issue for many hunters includes losing or dropping items like gloves, arrows, hats, and bows. These items will directly affect hunters well being and fun on their trips. Our project design allows hunters to have a safer and more enjoyable experience in the outdoors. We are introducing a recovery system to retrieve their gear like Bows, Bags, and medical equipment in a safe manner without putting the hunter at risk. Our product doesn\u27t prevent hunters from dropping items but instead offers a revolutionary way to help them get their fallen gear back without having to climb down the tree or risk falling and ruining the hunt
Microwave Spectrum and Analysis of 2,3,6-trifluorophenol
No full textWe have measured the microwave spectrum of 2,3,6-trifluorophenol for the first time. Using a custom-built chirped-pulse Fourier transform microwave (CP-FTMW) spectrometer, we measured the spectrum in the 8 – 18 GHz range. To support our analysis, we performed ab initio calculations at the B3LYP/6-311+G(d,p) level of theory. We will present on the spectrometer design, the rotational constants of the 2,3,6-trifluorophenol, and the distortion constants of the same molecule. This study is one of a series of studies performed in our laboratory on di- and tri-fluorophenols
The Creation of a Prototype Dashboard Indicating COMET Bus Transit Ride Reliability Using General Transit Feed Specification Data
No full textIn response to the escalating impact of climate change, there is a growing imperative for the widespread adoption of alternative transportation methods throughout the United States. However, challenges within public transport, particularly reliability issues involving delays and service disruptions, pose significant hurdles to an optimal commuting experience. This paper focused on enhancing the reliability of bus transit services, specifically within the context of the COMET (Central Midlands Regional Transit Authority) system. The current application that the COMET utilizes, Transit, restricts readily accessible transit line information by implementing a paywall for lines outside the user\u27s area. Thus, this project aimed to develop a dashboard with information regarding the transit system’s predicted arrival times, stop times, average travel time, and so on. The study employed publicly available General Transit Feed Specification (GTFS) data, encompassing real-time (rt-GTFS), obtained from the COMET Trillium Transit database. By utilizing a Kalman filter, various analyses are conducted on the aforementioned data to interpolate bus positions based on periodic measurements, average travel time calculations, etc
Cost Effective Turbidity Meter
No full textCurrent lab-grade turbidity meters are oftentimes too costly for the majority of nonprofits, including global organizations like Water Mission. The typical turbidity meter suited for industrial settings (notably the HACH meter) can cost upwards of $4000. This is why creating a cheaper, but still accurate, meter is vital for organizations with financial restraints and communities who do not have enough money. Turbidity meters are used to ensure that water is safe to drink or if the water needs to be treated. This research focuses on the cheap DfRobot meter being an alternative to expensive industrial meters. Although the hardware of the meter is adequate, the code of the meter is riddled with errors. The meter takes measurements in volts and the software converts these measurements into NTU. The code in the DfRobot meter is corrected by establishing the relationship between Volts and Nephelometric Turbidity Units(NTU) by measuring water samples with different known turbidities and recording the volts from the cheap meter and NTU from the accurate one. The actual relationship is linear and as the volts increase, the turbidity (NTU) decrease. The cheaper meter is then tested against the more expensive, but perfectly accurate HACH 2100 meter. A Paired T-test is used to confirm that the DfRobot meter is suitable for industrial, humanitarian, and professional purposes