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Effect of Lung Carcinoma Exosomes on the Tumor Microenvironment and Characterization of Contents as Novel Therapy
Cancer uses intercellular communication to induce tumor growth and metastasis. Fibroblasts can become specifically transformed and associated with cancer to aid in the process. Extracellular vesicles, specifically exosomes, contain proteins, RNA, and DNA that are taken up by local cells to affect cellular behavior. Exosomes were isolated from lung carcinoma using total exosome isolation reagent and quantified. These exosomes were used to treat lung fibroblasts and enrich lung carcinoma cells, and the effects of exosomes on cancerous properties, cell viability and cell migration, were studied. An increase of cell viability was found with exosome treatment for both cell lines while migration only increased for enriched lung carcinoma cells. Additionally, mass spectrometry-based proteomics of exosomes isolated from hepatocellular carcinoma was analyzed. Through a survey of differentially expressed proteins between high and low grade hepatocellular carcinomas against normal liver cells, several pathways of interest were identified. Some common motifs in underexpressed genes were the regulations of cell signaling, cell metabolism, and cell death. A study of miRNAs in exosomes along with potential theraputic exosome uses was performed
How Gender Biases Affect Perceived Competence
We investigated whether participants\u27 gender biases had an effect on their ability to learn a new task. To study this, participants either watched a knot tying or macrame tutorial taught by a male or female instructor. Participants then completed two surveys, one that measured their perceived competence on the task, and another that measured their own gender biases. To measure gender biases we used the Ambivalent Sexism Inventory which had no effect on the results. No significant results were found between instructor gender and type of task when measuring perceived competence
From the Ouachitonian : Drs. Amy and Doug Sonheim
The infectious laughter of Dr. Amy Sonheim and the careful clicking of a keyboard from Dr. Doug Sonheim would help fill the language and literature department for years before their combined retirement from Ouachita in Spring 2022. In the years that they have worked at Ouachita, the couple has made some amazing changes to the university
From the Ouachitonian : Gabe Goodman
It was the fourth quarter with 57 seconds left. The Henderson Reddies and the Tigers were tied at 28-28. The Ouachita fans were silent as Gabe Goodman, a junior finance major from Arkadelphia, Ark., prepared for a 53-yard field goal to win the game. The Henderson Reddies’ cheers shook Cliff Harris Stadium as he approached the football
Hope grows in a nourished imagination: 2022 Convocation address
I like Chapel and seldom miss attending. I like being with students in Chapel. There are probably fewer than 100 universities in the country where essentially the entire student body can all be together. In my first six years, I’ve appreciated how students respect and engage in Chapel. I believe it’s an important part of what makes Ouachita, Ouachita. Each academic year, we choose a theme. This year, it’s “Love God and Love Learning” from our vision statement. We also develop a commemorative patch. You’ll find all the patches on my backpack. And it makes me happy when others display their patches
Jonathan Sandy in a Senior Percussion Recital
This is the program for the senior percussion recital of Jonathan Sandy held on April 22, 2022, in the McBeth Recital Hall in the Mabee Fine Arts Center
Dr. Jeremy Greer returns to Ouachita as the next dean of the Pruet School of Christian Studies
Dr. Jeremy Greer, a 1998 Ouachita graduate and second generation pastor, has completed his first semester as the new dean of Ouachita’s Pruet School of Christian Studies. Greer has long ties to the university as well as Arkansas Baptists in addition to higher education experience through teaching and administrative roles.
“My overarching feeling is gratitude,” Greer said. “I am grateful to once again be an Arkansas Baptist. I am grateful to serve an institution for which I have such deep affections and appreciation. I am grateful to serve alongside faithful men and women whom God has used to transform me and countless others.
“As we look into the future,” he added, “we can know that God will continue to work and will continue to call young men and women into service. I trust that he will continue to use the Pruet School to train these called ones and send them out. This is our task, and we will be faithful to it.
Robert S. Moore Jr. given distinguished alumni award
Arkansas Highway Commission Chairman Robert S. Moore Jr. received the Distinguished Alumni Award for Public Service to the State of Arkansas from Ouachita during an August luncheon held on campus in his honor.
The award was presented to Moore by Dr. Ben R. Sells, Ouachita president, and Taylor King, chair of the university’s Board of Trustees