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Phase variation and mechanical properties of waste calcium carbonate to substitute quartz in composite slab production
No full textOwing to the fast-emerging nature and rapid advancements in the construction industry, huge volumes of marble dust (MD) are generated as reject during slab cutting in marble processing, causing significant environmental hazards. Nowadays, quartz composite slabs have increasingly been preferred in building works due to their excellent hygienic property and mechanical strength. Composite slab is produced using micronized quartz as filler, the grinding of which is an energy-intensive process. Substitution of micronized quartz with MD at different percentages was investigated in natural form and after roasting. Natural MD offered appreciable physical properties closer to those of a quartz composite slab. Physical properties slightly retrograded by quartz supplementation in the raw form. Roasting the filler led to the formation of rounded Ca–silicate. Wollastonite was the first phase formed after sintering at the lowest MD percentage and shortest roasting times. Larnite became dominating phase first by increasing MD percentage and roasting time, and then calcio-olivine formed. Physical characterization test results demonstrated that hardnesses of new phase and particle shape were the key parameters that improved slabs’ mechanical properties of. Hard rounded larnite particles improved mechanical behavior of slabs having the synergic effect of quartz, whereas wollastonite did not show a significant effect
The effects of the Rheum ribes plant extract on inflammation, extracellular matrix remodeling, and obesity suggest a therapeutic potential
No full textBackground: The prevalence of obesity is increasing in the world, and the Type II diabetes associated with obesity led researchers to seek alternative methods to treat these two chronic diseases. In the case of obesity and diabetes, changes occur in the levels of inflammatory mediators. A study was conducted to investigate the molecular mechanism of the Rheum ribes L. plant regarding obesity and inflammation. Methods and Results: Differentiated 3T3-L1 mouse cell lines were used as an experimental model. A dose–response relationship was established to determine at what dose and time of treatment the R. ribes L. plant extract would act effectively. To assess expression on the transcriptional level, q-PCR analyses were performed. The primers to evaluate the expression levels of genes such as Dgat1, Lpl, Fasn, ColV, Il-6, and Mcp1, which are known to be associated with obesity and insulin resistance, inflammation, and cell skeletal restructuring was designed using NCBI sequences. 18S was chosen as the housekeeping gene for normalization. Conclusion: It was found that applying 50 µg/mL and 100 µg/mL of R. ribes root extract to 3T3-L1 adipocyte cells for 24 and 48 h resulted in anti- obesity and anti-inflammatory effects on the genes examined at the transcriptional level. It is an effective study to understand the molecular mechanisms by which R. ribes, which is known to have anti-diabetic, anti-obesity and anti- inflammatory activities, and to establish a link between these activitie
Citrus Honeys from Three Different Regions of Turkey: HPLC-DAD Profiling and in Vitro Enzyme Inhibition, Antioxidant, Anti-Inflammatory and Antimicrobial Properties with Chemometric Study
No full textThe objectives of the present study are to compare the phenolic profiles and biological activities of 15 citrus honey samples from three different locations in Turkey using a chemometric approach. The HPLC-DAD analysis was used to determine phenolic profiles. Nineteen phenolic compounds were identified. Gallic acid (107.14–717.04 μg/g) was recorded as the predominant compound. AF (Antalya-Finike) had the highest antioxidant activity in ABTS⋅+ (IC50: 18.01±0.69 mg/mL), metal chelating (IC50: 6.20±0.19 mg/mL) and CUPRAC (A0.50: 12.05±0.68 mg/mL) assays, while it revealed the best anti-inflammatory activity against COX-2 (17.28±0.22 %) and COX-1 (43.28±0.91 %). AM (Antalya-Manavgat) was the most active in β-carotene-linoleic acid (IC50: 10.05±0.19 mg/mL), anti-urease (38.90±0.69 %), anti-quorum sensing and antimicrobial activities. AKO1 (Adana-Kozan-1) in DPPH⋅ (IC50: 34.25±0.81 mg/mL) assay, AKU1 (Antalya-Kumluca-1) in tyrosinase inhibition activity (37.73±0.38 %) assay, AKU2 (Antalya-Kumluca-2) in AChE (10.55±0.63 %) and BChE (9.18±0.45 %) inhibition activity assays showed the best activity. Chemometric tools were applied to the phenolic compositions and biological properties. PCA and HCA ensured that 15 citrus honey samples were grouped into 3 clusters. The results showed that myricetin, kaempferol, vanillin, protocatechuic acid, rosmarinic acid, rutin, vanillic acid, gallic acid, catechin and p-hydroxyphenyl acetic acid are phenolic compounds that can be used in the classification of citrus honeys
An Emphatic Perspective: How Do Pre-School and Classroom Teacher Candidates Interpret Child Abuse and Neglect?
No full textThis study aims to evaluate the perceptions of teacher candidates regarding child abuse and neglect as well as propose preventive measures. Utilizing a phenomenological design, a qualitative research method, the study focuses on understanding the unique experiences of individuals. The sample was selected through purposive random sampling and homogeneous sampling techniques. Data was gathered from 13 participants, including 7 elementary education candidates and 6 pre-school education candidates, at the Faculty of Education of a public university in Turkey during the 2018-2019 academic year. The participants' work was analyzed using "content and descriptive analysis" methods.The study found that teacher candidates depicted child abuse and neglect as "a distressing situation that makes children unhappy." In their drawings, they predominantly used black to represent abused children, while abusers were symbolized through metaphors such as "dirty, darkened hands." The research demonstrated that the teacher candidates were capable of defining child abuse, understanding its various forms, empathizing with the emotions of abused children, and proposing potential solutions
The Effect of Fish Meal and Plant-Based Diets on the Growth and Nutritional Composition of White Worms (Enchytraeus albidus Henle, 1837) in Various Substrates
No full textIn this study, the growth and nutritional composition of Enchytraeus albidus (white worm) were investigated using different combinations of culture substrates and feeds. The aim was to determine the utilization of White worm for recycling the fish feeds in case of expiration. The white worms were either given a plant-based diet or a fish feed-based diet (commercial extruded Seabass feed) in four different culture substrates (rice husk, peat, cocopeat, garden soil). There were altogether eight experimental groups with triplicates. The initial stocking density of white worms was 150 worms/unit (2.2 Liters of cylindrical containers), and all the experiments were carried out in the dark at a constant temperature at 18oC. Worms were collected from the substrate by heat treatment and the counting was done manually, using dissection tools. Proximate composition of the produced white worms was measured with regard to given ratios of the protein, carbohydrate and lipid sources provided from the feed materials. The plant-based diet yielded the highest worm density of the study (2220 worms/unit) while the garden soil was used as substrate. In comparison, the fish feed-based diet fed white worms reached a significantly lower density (627 worms/ unit) although the optimal nutritional value for the fish diet was ensured. These results showed that the carbohydrate content of the feed for white worm should be adjusted for optimal growth. Furthermore, the use of a combined plant- and fish feed-based diet can result in high growth performance and improved nutritional value during fish feed production
A Survey on The Effects of R&D, Advertising Spendings on Businesses Revenue and The Competitive Parity Method
No full textOne of the main problems faced by business managers from the past to the present is how to use their resources in the most profitable way. It is the planning of what, where, how much, when, how, for whom it will be produced or presented, and their financing. The aim of this study is to examine the effects of advertising spendings on operating profit, which is the most important element of the promotion mix in the marketing function with R&D spendings using regression analysis, additionally to explain how the competitive parity method has an impact on budget planning by performing cluster analysis by sector
The effect of fractional order mathematical modelling for examination of academic achievement in schools with stochastic behaviors
No full textAcademic achievement is very important, as it enables students to be well-equipped for professional and social life and shapes their future. In the case of a possible academic failure, students generally face many cognitive, social, psychological, and behavioral problems. This problem experienced by the students has been addressed with the mathematical model in this study. This mathematical model will be handled with the help of the fractional operator, and the existence, uniqueness, and positivity of the solutions to the model equation system will be examined. In addition, local and global stability analyses of the equilibrium points of the model are planned. Numerical simulations are performed with different values of fractional orders and densities of randomness. This study is very important in terms of its original and multidisciplinary approach to a subject in the field of social sciences
A multicenter retrospective analysis of patients with nasopharyngeal carcinoma treated in IMRT era from a nonendemic population: Turkish Society for Radiation Oncology Head and Neck Cancer Group Study (TROD 01-001)
No full textBackground: We aimed to evaluate patients with nasopharyngeal carcinoma (NPC) in a nonendemic population. Methods: In a national, retrospective, multicenteric study, 563 patients treated with intensity modulated radiotherapy at 22 centers between 2015 and 2020 were analyzed. Results: Median age was 48 (9–83), age distribution was bimodal, 74.1% were male, and 78.7% were stage III-IVA. Keratinizing and undifferentiated carcinoma rates were 3.9% and 81.2%. Patients were treated with concomitant chemoradiotherapy (48.9%), or radiotherapy combined with induction chemotherapy (25%) or adjuvant chemotherapy (19.5%). After 34 (6–78) months follow-up, 8.2% locoregional and 8% distant relapse were observed. Three-year overall survival was 89.5% and was lower in patients with age ≥50, male sex, keratinizing histology, T4, N3 and advanced stage (III-IVA). Conclusions: Patients with NPC in Turkey have mixed clinical features of both east and west. Survival outcomes are comparable to other reported series; however, the rate of distant metastases seems to be lowe
The Role of Ali Suad’s Article “Religious Literature” in Turkish Religious Literature
No full textİslami Türk edebiyatı hakkında derli toplu bir inceleme yapabilmek için, Türk dinî edebiyatına dair öncü çalışmalar oldukça önemlidir. Dinî edebiyat kavramının Türk edebiyatı içindeki anlamı ve yerinin saptanması, söz konusu öncü çalışmaların değerlendirmesiyle mümkün olabilir. Türk dinî edebiyatı üzerine düşünen öncü makalelerden biri olan ve Ali Suad tarafından Mihrâb mecmuasında kaleme alınan “Dinî edebiyat” başlıklı makale de Türk dini edebiyatını teorik olarak konu edinen erken makalelerdendir. Yazarın ilgili makalesine odaklanan bu çalışmada ise henüz 1920’lerin başında dinî edebiyatın iki farklı döneme ayrıldığını ortaya koyan bir Osmanlı aydınının Türk dinî edebiyatı hakkındaki düşünceleri tartışılmıştır. Çalışmada ayrıca, Ali Suad’ın “mutlak” ve “mukayyed” kavramlarını kullanarak ayırdığı, Türk edebiyatının eski ve yeni dönemlerinde kaleme alınan eserler ve bu eserleri üreten edebî şahsiyetlerden bahsedilmiştir. Çalışmanın sonunda Türk dinî edebiyatının Türk edebiyatı içindeki yeri, Türk dinî edebiyatının teorik arka planını kuran metinlerden biri olan “Dinî edebiyat” makalesine odaklanarak sorgulanmıştır.The article “Religious literature”, one of the pioneering articles on Turkish religious literature, written by Ali Suad and published in Mihrâb journal is one of the early articles on the theory of Turkish religious literature. This study which focuses on the author’s related article provides the opportunity to see the thoughts about Turkish religious literature of an Ottoman intellectual from the early 1920’s, who revealed that religious literature was divided into two different periods. Moreover, it tells about the works written in the old and new periods, which Ali Suad distinguishes by using the concepts of “absolute” and “bounded”, and how the literary figures who produced these works established and continued Turkish religious literature. At the end of the study, the place of Turkish religious literature in Turkish literature is questioned by focusing on “Religious Literature”, one of the texts that establish the theoretical background of Turkish religious literature
Aspirin Use in Patients Aged 80 years and over in Turkey: Snapshot of Results from the ASSOS Study
No full textObjectives: Acetylsalicylic acid (aspirin) is commonly used with various indications, especially in the elderly population. This study aims to evaluate the prevalence of polypharmacy and aspirin use in patients aged ≥80 years. Methods: The ASSOS trial is a cross-sectional, national registry study. This nonrandomized study was conducted by 30 cardiologists in 14 cities on the elderly (over the age of 80 years) who used aspirin (80–325 mg). Polypharmacy is described as an intake of five or more medicines daily. Results: A total of 309 patients were included in the study, and 146 (47.2%) of them were females. Aspirin treatment for primary prevention (PP) was reported to be given to 101 (32.7%) patients, and polypharmacy was detected in 198 (64.1%) patients. Major gastrointestinal bleeding was reported in 7 (3.5%) patients in the polypharmacy group and 0 (0.0%) patients in the without polypharmacy group (p=0.043). Minor bleeding was reported in 58 (29.3%) patients in the polypharmacy group and in 8 (7.2%) patients in the group without polypharmacy (p[removed