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A new species of Saxifraga (Saxifragaceae) from northeastern Anatolia, Turkey
No full textSaxifraga kavrunensis, a new species endemic to Turkey, is described and illustrated. Samples from its natural population were collected from the Kaçkar Mountains in Rize Province. Although it has similar features to S. paniculata subsp. paniculata, it differs in its longer multi-flowered stem and maroon-spotted corolla. In this study, the diagnostic characteristics of S. kavrunensis were elucidated at the morphological, micromorphological and molecular level. In the molecular-based phylogenetic analyses, S. kavrunensis was compared with S. paniculata subsp. paniculata, to which it bears the closest morphological resemblance. After PCR analyses, reproductive band profiles were obtained from three of the eighteen ISSR primers tested. The 66 polymorphic band profiles, ranging from 230 bp to 4000 bp, were obtained from the agarose gel electrophoresis images of these three primers. According to a distance matrix based on the Jaccard coefficient, significant variation was detected at the species level, with indices varying between 0.395 and 0.614 between both species
The use of coffee for the prevention of ileus following abdominal surgery: A review of the current evidence
No full textPostoperative ileus (POI) is a form of intestinal paralysis that is seen especially after surgical procedures performed by entering the abdominal cavity. POI is common, particularly after abdominal surgery, with an incidence of 8-30%. The initial phase of postoperative paralytic ileus is treated with decompression using a nasogastric tube to correct electrolyte imbalances, with analgesia applied as needed. Prokinetic compounds have been used to prevent ileus and control pain (such as serotonin receptor antagonists, neostigmine, alvimopan, and ghrelin agonists), along with early mobilization, minimally invasive surgery, early introduction of solid food into the diet, thoracic epidural analgesia, and fluids. Coffee has been shown to accelerate postoperative bowel movements. However, despite extensive research on the physiological impacts of coffee, little is acknowledged regarding how it affects the gut. Coffee increases colonic motility within 4 min of consumption. In the postoperative period, the number of intestinal vocals heard by auscultation of intestinal vocals, first gas and first defecation times of patients who consume coffee are smaller/shorter than patients who do not consume coffee. Patients who drink coffee also have shorter hospital stays
Magnetic properties of the FCC and BCC phases of (MnFeCoNi)(80)Cu(20_x)Z(x()Z(1)& nbsp;Al, Ga) high-entropy alloys
No full textIn this work, the FCC-BCC phase transition in (MnFeCoNi)80Cu20 (Al, Ga) high entropy alloys were investigated on the basis of structural, magnetic, hardness and thermal expansion properties. It is found that the equiatomic MnFeCoNiCu alloy is FCC and exhibits mixed ferromagnetic/anti-ferromagnetic interactions with a Curie temperature, , close to room temperature. However, the BCC structure emerges with increasing amount of Al (10 at%) and Ga (15 at%) with additional ferromagnetic interactions and associated. It is evidenced that in terms of the valence electron concentration and the average magnetic moment values, the investigated HEAs obey the Slater-Pauling rule in a region close to the Heusler alloys. Additionally, they may exhibit similar physical properties like Invar property with low thermal expansion coefficient with the 3d-transition metal-alloys having same valence electron concentration
Synthesis, spectroscopic characterization, crystal structure and biological properties of novel co-crystal copper(II) complex containing dioxime ligand
No full textThe title compound, co-crystal [(aqua) (1E,1′E,2E,2′E)-2,2′-(propane-1,3-diylbis(azaneylylidene)) bis(2-phenylacetaldehyde)dioximato] copper(II)chlorate, [Cu(HL1)ClO4]3, was synthesized from 1,3-diaminopropane and isonitrosoacetophenone. Its molecular and crystal structures were determined by single crystal X-ray analysis. The asymmetric unit of the newly synthesized co-crystal contains three crystallographically independent copper complex molecules and three uncoordinated chlorotetraoxide anions. The DNA binding activity of the Cu(II) complex was carried out by absorption spectra measurements and fluorescence spectroscopy. The results revealed that the binding mode of the complex with DNA is via minor groove. The concentration and time dependent DNA cleavage studies including cleavage mechanism of the complex were performed by employing gel electrophoresis assay, where the complex has been found to cleave supercoiled DNA with high efficiency. Topoisomerase I and IIα inhibition assays with Cu(II) complex were performed and complex showed strong inhibition against both enzymes. The cytotoxic activity of the complex was performed on human cell lines, lung carcinoma cell line (A549), colorectal adenocarcinoma cell line (HT29), hepatocellular carcinoma cell line (HepG2), breast cancer cell line (MDA-MB-231) and prostate cancer cell lines (LnCaP) by MTT assay. Annexin V, MMP and ROS assays were also performed. The complex was exhibited significant in vitro cytotoxicity against HepG2 and LnCaP
Generative Artificial Intelligence in the Hospitality and Tourism Industry: Developing a Framework for Future Research
No full textGenerative artificial intelligence (GAI) offers important opportunities for the hospitality and tourism (HT) industry in the context of operations, design, marketing, destination management, human resources, revenue management, accounting and finance, strategic management, and beyond. However, the implementation of GAI in HT contexts comes with ethical, legal, social, and economic considerations that require careful reflection by HT firms. The purpose of this study is to offer a critical examination of the effects of GAI applications across a broad spectrum of stakeholders in the HT industry, in an effort to integrate practical and academic insights and foresights and drive academic research forward. Through the contributions of a purposeful selection of scholars, educators, and industry-practitioners, along the tenets of the stakeholder theory of the firm, this study highlights the potential challenges and opportunities of GAI and considers how academics can navigate the (research) complexities of this rapidly evolving technological phenomenon
Letter to the Editor: “The Effect of Bariatric Surgery on Irisin Level: a Systematic Review and Meta‐analysis”
No full textLetter to edito
AFORS-HET simulation for investigating the performance of ZnO/n-CdS/p-CdTe /Ag solar cell depending on CdTe acceptor concentration and temperature
No full textIn this study, a single junction dc photovoltaic solar cell simulation was carried out. ZnO/n-CdS/p-CdTe/Ag cell properties were investigated through the recognized 'Automatic Heterostructure Simulation (AFORS-HET)'. In the theoretical simulation process, the temperature was between 200 K and 400 K and the acceptor concentration of the CdTe layer was in the range of 1014 cm-3-1019 cm-3. The variation of Voc (open circuit voltage), Jsc (short circuit current density), FF (filling factor) and ii (efficiency) values with T (temperature) and Na (acceptor concentration) were investigated. It was observed that as Na increased, Voc values increased and Jsc values decreased. Voc, FF and ii decreased as the temperature was increased. Also, the sensitivity of FF to Na increased for acceptor concentration values greater than 1018 cm-3. It has been also shown that the filling factor decreased with photovoltaic current. ZnO/n-CdS/p-CdTe/Ag cells with an acceptor concentration greater than 1018 cm-3 exhibited high efficiency for all studied temperatures
A Series-Based Deep Learning Approach to Lung Nodule Image Classification
No full textAlthough many studies have shown that deep learning approaches yield better results than traditional methods based on manual features, CADs methods still have several limitations. These are due to the diversity in imaging modalities and clinical pathologies. This diversity creates difficulties because of variation and similarities between classes. In this context, the new approach from our study is a hybrid method that performs classifications using both medical image analysis and radial scanning series features. Hence, the areas of interest obtained from images are subjected to a radial scan, with their centers as poles, in order to obtain series. A U-shape convolutional neural network model is then used for the 4D data classification problem. We therefore present a novel approach to the classification of 4D data obtained from lung nodule images. With radial scanning, the eigenvalue of nodule images is captured, and a powerful classification is performed. According to our results, an accuracy of 92.84% was obtained and much more efficient classification scores resulted as compared to recent classifiers. © 2023 by the authors
Investigation of Pomegranate ( Punica granatum L.) Flowers' Antioxidant Properties and Antibacterial Activities against Different Staphylococcus Species Associated with Bovine Mastitis
No full textMastitis is one of the most considerable and costly diseases for dairy herds, and Staphylococcus spp. is known to be the main causative agent. Although antibiotics are widely used in the treatment of mastitis, this can cause both antibiotic residues in milk and the risk of antibiotic resistance occurrence in bacteria. Thus, in recent years, researchers have focused on alternative treatments for this disease and plants extracts are investigated for this purpose. Pomegranate is widely used as a dye, ornament, and medicinal plants in the industry, and the species has a particularly high economic value in Turkey. This study aims to investigate in vitro the antioxidant and antibacterial properties of the pomegranate flower's extracts against different Staphylococcus species associated with bovine mastitis. To this aim, pomegranate flowers were collected from different regions in Turkey and extracts were prepared with three different solvents (methanol, ethanol, and water). The retention factor values of the ethanol extract were determined by thin-layer chromatography. The antibacterial activity tests were carried out via the disk diffusion method. In addition, the extracts were tested against the stable DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free radicals for antioxidant activity. Four retention factors (0.79, 0.67, 0.58, and 0.33 points) were found for the ethanol extract. The methanol extract showed the highest inhibition zones against coagulase-negative Staphylococcus-37 (CNS-37) and S. aureus-18. The lowest MIC was 6500 μg/mL. The highest antioxidant activity was observed in methanol extracts. As a result, the extracts of pomegranate flowers showed a high antioxidant and antibacterial potential against the examined mastitis pathogens
Formal Verification of Bit-Vector Invertibility Conditions in Coq
No full textWe prove the correctness of invertibility conditions for the theory of fixed-width bit-vectors—used to solve quantified bit-vector formulas in the Satisfiability Modulo Theories (SMT) solver cvc5— in the Coq proof assistant. Previous work proved many of these in a completely automatic fashion for arbitrary bit-width; however, some were only proved for bit-widths up to 65, even though they are being used to solve formulas over larger bit-widths. In this paper we describe the process of proving a representative subset of these invertibility conditions in Coq. In particular, we describe the BVList library for bit-vectors in Coq, our extensions to it, and proofs of the invertibility conditions