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Digital Collections of Sermons
No full textThis session focused on the Gateway to Early Modern Manuscript Sermons (GEMMS). The panel used their experience with GEMMS to discuss how the use of digital sermon collections has contributed to Sermon Studies, and how researchers might use such collections to open up new avenues of scholarship in the future. They also considered how to make digital collections more sustainable, and what creators of other digital sermon collections can learn from GEMMS. Presenters included Jennifer Farooq (Project Manager) and other members of the GEMMS team: Mary Morrissey (Advisory Board Member), Brent Nelson (Principal Investigator), Jeanne Shami (Principal Investigator), and Hannah Yip (Research Assistant)
On Hamilton cycle decompositions of complete multipartite graphs which are both cyclic and symmetric
Get PDFLet G be a graph with v vertices. A Hamilton cycle of a graph is a collection of edges which create a cycle using every vertex. A Hamilton cycle decomposition is cyclic if the set of cycle is invariant under a full length permutation of the vertex set. We say a decomposition is symmetric if all the cycles are invariant under an appropriate power of the full length permutation. Such decompositions are known to exist for complete graphs and families of other graphs. In this work, we show the existence of cyclic n-symmetric Hamilton cycle decompositions of a family of graphs, the complete multipartite graph Km×n where the number of parts, m, is odd and the part size, n, is also odd. We classify the existence where m is prime and prove the existence in additional cases where m is a composite odd integer
COVID-19 Disease and Viral Characteristics in a Long-Term Care Facility
Get PDFBackground
Due to the combination of age, comorbidities, and close living quarters, residents at long-term care facilities (LTCFs) are at particularly high risk of severe symptoms and death due to COVID-19.
Methods
This cross-sectional study examines the relationship between demographic characteristics, symptom severity, and length of viral shedding in 49 residents testing positive for SARS-CoV-2 at a LTCF in West Virginia (WV).
Results
Over half of the residents were asymptomatic, while nearly a quarter experienced severe symptoms. Women were more likely to be asymptomatic, and age was not associated with symptom severity. While no specific medical condition was associated with symptom severity, having more chronic illnesses was associated. The length of time from initially positive to PCR negative ranged from 2 to 63 days, with an average of 29 days.
Conclusion
Given the variability in PCR testing reliability, 30 days of isolation and two consecutive negative PCR tests are recommended before reintegrating residents
Factors Associated with Mutations: Their Matching Rates to Cardiovascular and Neurological Diseases
Get PDFMonogenic hypertension is rare and caused by genetic mutations, but whether factors associated with mutations are disease-specific remains uncertain. Given two factors associated with high mutation rates, we tested how many previously known genes match with (i) proximity to telomeres or (ii) high adenine and thymine content in cardiovascular diseases (CVDs) related to vascular stiffening. We extracted genomic information using a genome data viewer. In human chromosomes, 64 of 79 genetic loci involving \u3e25 rare mutations and single nucleotide polymorphisms satisfied (i) or (ii), resulting in an 81% matching rate. However, this high matching rate was no longer observed as we checked the two factors in genes associated with essential hypertension (EH), thoracic aortic aneurysm (TAA), and congenital heart disease (CHD), resulting in matching rates of 53%, 70%, and 75%, respectively. A matching of telomere proximity or high adenine and thymine content projects the list of loci involving rare mutations of monogenic hypertension better than those of other CVDs, likely due to adoption of rigorous criteria for true-positive signals. Our data suggest that the factor–disease matching rate is an accurate tool that can explain deleterious mutations of monogenic hypertension at a \u3e80% match—unlike the relatively lower matching rates found in human genes of EH, TAA, CHD, and familial Parkinson’s disease
Side-to-differences of medial elbow anatomy adaptations in youth throwing athletes
Get PDFBackground: Injuries to the medial elbow are common in overhead sports, with the most common occurring at the medial/ulnar collateral ligament (UCL). Injury to the UCL is associated with elbow joint laxity which tends to develop over time in athletes who place their elbows under chronic valgus forces like those present during throwing. 27, 37 This instability is well documented in professional, collegiate, and high school athletes.
Purpose: The purpose of this study was to investigate the medial elbow joint width and common flexor tendon thickness in the arms of youth baseball players. The hypotheses were (1) the medial elbow joint space would be greater on the dominant arm compared to the non-dominant arm in a resting position, (2) the medial elbow joint space would be greater on the dominant arm compared to the non-dominant arm in the stressed position; and (3) the common flexor tendon would have a greater thickness on the dominant arm compared to the non-dominant arm.
Methods: Six participants were included in this investigation.. The width of the medial elbow was measured on ultrasound images of the medial elbow and common flexor tendon. The medial elbow joint space was measured at rest and with an applied valgus stress.
Results: There was no significant difference in medial elbow joint space width between the dominant and non-dominant sides at rest or with an applied valgus stress. There was no significant difference in common flexor tendon thickness at the elbow between the dominant and non-dominant sides within subjects. The mean medial elbow joint space width at rest was 3.39mm ± 0.96mm on the dominant side and 3.47mm ± 0.87mm on the non-dominant side. When a valgus stress was applied, the dominant side mean increased to 3.92mm ± 1.02mm and the non-dominant side increased to 4.04mm ± 1.04mm. The mean flexor tendon thickness was 3.8mm ± 0.54 on the dominant side and 3.92mm ± 0.59mm on the non-dominant side.
Conclusion and Practical Significance: No side-to-side difference in medial elbow joint space width or flexor tendon thickness was observed in youth baseball/softball athletes. These findings are expected in youth throwers due to their relative inexperience with overhead throwing and lack of accumulated stress on the medial elbow. Maintaining the stability of the elbow as youth throwing athletes age is a vital step in preventing costly injury later in their careers
Help Patients Safely Handle Medications to Improve Adherence
Get PDFMedication nonadherence can cause many drug-related adverse effects (AEs), and pharmacists are in a prime position to use every patient interaction as an opportunity to address barriers, improve adherence, and increase the safe management of medications
Moore-Penrose Inverses of the Signless Laplacian and Edge-Laplacian of Graphs
No full textThe signless Laplacian Q and signless edge-Laplacian S of a given graph may or may not be invertible. The Moore-Penrose inverses of Q and S are studied. In particular, using the incidence matrix, we find combinatorial formulas of the Moore-Penrose inverses of Q and S for trees. Also, we present combinatorial formulas of the inverses of Q and S for odd unicyclic graphs