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Strategies to Help Eliminate Drug Exposure Risks in the Workplace
No full textEnsuring the safe handling of hazardous drugs (HDs) has been a top priority in health care settings. The American Society of Health-System Pharmacists (ASHP) has continually updated guidelines and standards to guide pharmacists in safely handling HDs
Artificial Intelligence Is Revolutionizing Controlled Substance Diversion Detection
Get PDFIn community and institutional health care sectors, artificial intelligence (AI) use is expanding. AI is being tapped broadly in operations, customer service, and scheduling, with major pharmacy chains such as Kroger, CVS, and Walgreens, already starting to implement AI applications in their pharmacies. So far, Kroger has begun to use AI for employee onboarding and training processes, CVS is applying AI in negotiations with suppliers, and Walgreens is using it to streamline vaccine scheduling. With these advances in major pharmacy chains, the next extensive application for AI has become clearer: diversion monitoring. Diversion occurs in health care settings when a drug is redirected from its lawfully prescribed purpose to illicit use, regardless of criminal intent (eg, sharing medication with family or friends)
In Memoriam Rolando Teruel Ochoa (1974 – 2023)
Get PDFThis is an obituary of Rolando Teruel Ochoa (1974–2023), a great Cuban arachnologist. A full list of his works is appended, as well as a list of scorpions and other arachnids described by Rolando
Trends in the Number of Authors and Institutions in Papers Published in AJPE 2015-2019
No full textObjective. To investigate the number of authors and unique institutions per paper published in the American Journal of Pharmaceutical Education (AJPE) in 2015 through 2019, and to examine the number of authors and unique institutions for papers that were nominated for the Rufus A. Lyman Award in the same period.
Methods. Articles published in AJPE from 2015 through 2019 were reviewed. Data collected for each article included article type, number of authors, and number of institutions.
Results. Of the 811 articles published in AJPE during this period, the number of authors increased significantly from a mean (SD) of 3.5 (1.8) to 4.5 (2.2). The number of unique institutions also increased significantly from 1.7 (1.1) to 2.4 (1.8).
Conclusion. There is a trend toward a greater number of authors and unique institutions for the publications in one pharmacy education journal. Explanations for this trend may include pressure to publish, increased research complexity, and expanded interprofessional collaboration
Feeding on Butterflies: Lucille Sharpe as the Monstrous Woman in Crimson Peak
No full textGothic literature, which is based in dark scenery, melodramatic narratives, and feelings of dread and horror, often focuses on women and the terror that accompanies their vulnerable position in the patriarchal order. In recent years, the Gothic has been revived, the genre taking on a new light that is referred to as “Neo-Victorian” which takes a contemporary approach to genres of the long Victorian era, including the Gothic. These narratives use and subvert the themes and tropes of Gothic literature to reveal and explore important issues as they relate to both time periods, one example being women’s place in society. In his 2015 film Crimson Peak, Del Toro also takes classic Gothic tropes involving women, such as the “Mad Woman in the Attic,” the home as a site of patriarchal terror, and women’s lack of agency, and subverts them to create a Neo-Victorian narrative that not only focuses on women but is controlled by women. This paper will explore the ways in which the film subverts classic Gothic portrayals of gender to create a narrative that reverses gender roles, specifically regarding the character of Lucille Sharpe. By exploring the character of Lucille using feminist and psychoanalytical lenses, I argue that, through her control over Allerdale Hall and her brother, Thomas, Lucille is shown as a monstrous female figure whose feminine control upsets the patriarchal order by crossing and erasing gender binaries, which is shown through the deteriorating state of the Sharpe ancestral home and Lucille’s untraditional feminine power
Hypermasculinity and Gender Performance Among Adolescent and Teenage Boys
No full textThe overarching goal of this study is to explore hypermasculinity and the gender performance of young boys in middle and high school. More specifically, this project investigates how and to what extent adolescent and teenage boys exhibit hypermasculinity and gender performance when placed in groups of similarly-aged boys. This study allows us to determine what, if anything, influences a hypermasculine ideal, if a hypermasculine ideal exists in the school setting at all, and what attitudes surrounding gender performance exist in the school. Data collection activities (i.e., observations and survey) are taking place at Collins Career and Technical Center. More specifically, surveys are being conducted at Collins Career and Technical Center on the campus with teachers of any subject. Fieldwork is being conducted in several classrooms at the school where a large groups of boys are being taught. The benefits of this research are to advance scholarship on hypermasculinity and gender performance among adolescent boys
Evictions: Huntington, West Virginia
No full textTitle: Evictions: Huntington, West Virginia
Kristi M. Fondren, Professor and Principal Investigator, Marshall University Matthew Adkins, Student, and Co-Investigator, Marshall University
The Purpose of the Research: The overall purpose of this study was to evaluate why the eviction rate in Huntington, WV is higher than the national average.
The Scientific or Scholarly Rationale: The primary goal of this research project was to answer the following question: What is happening in Huntington, West Virginia that is leading to higher rates of people being evicted, a rate which is higher than the national average? The national average according to Evectionlab.org (a national database and a government-sanctioned website) is that 2.3% of all renters will and do face eviction as of 2016. This website also ranks Huntington, WV as 114 out of every city in 13 total states surveyed. This is around 80 million different records associated with evictions. In 2016 alone Huntington had 616, ranking the city at 53 in a total number of evictions. This research project also provides more up-to-date information regarding rates of eviction in Huntington pre- and post-pandemic.
Complete Inclusion/Exclusion Criteria: Individuals were selected on their availability and willingness to participate, as well as on their experiences with eviction. The main purpose was to get at the root causes of eviction, landlords, those never evicted, housing corporations, and those who provide overnight accommodations (e.g., hotels, motels, inns)
High body mass index changes Peri-tumor adipose tissue which in turn promotes triple negative breast cancer
Get PDFCancer is one of the leading causes of death worldwide, responsible for over half a million deaths each year. There are multiple risk factors associated with the development of cancer. Some of these risks include genetics, smoking, and most recently, obesity (Lewandowska et al., 2019) (De Pergola & Silvestris, 2013). Research has shown that obesity is linked to the promotion of fourteen different cancers, including aggressive triple negative breast cancer (TNBC). Patients that are obese are more likely to develop cancer (Park et al., 2014). In addition, if the patient is obese at the time of a cancer diagnosis, they tend to have a larger tumor size and higher tumor grade (Neuhouser et al., 2015; Thompson et al., 2021; Yang et al., 2011). According to the world health organization, 41.9% of the world’s population is obese. While the link between obesity and its impact on the clinical outcome of cancer has been made, the mechanism by which obesity promotes cancer remains understudied, especially in TNBC. TNBC is the deadliest form of breast cancer due to the limited amount of treatment options and aggressive phenotype. The role of obesity in TNBC remains understudied compared to estrogen receptor positive breast cancer. This work provides insight into the role of obesity on the pathogenesis of TNBC. In this study deidentified peritumor breast adipose tissue was obtained from breast cancer patients being treated by the Edwards Comprehensive Cancer Center. Peritumor breast adipose tissue was cultured in cell culture media for 24 hours, and media containing adipose tissue secretions was collected. Peritumor breast adipose tissue obtained from patients with BMIs \u3e 30 were deemed high BMI adipose-derived secretome (ADS), conversely, BMI \u3c 30 was deemed low BMI ADS. TNBC MDA-MB-231 and MDA-MB-436 cells were treated with high BMI ADS or low BMI ADS in serum free media. Cell migration and invasion assays were performed on treated TNBC cells. Images were taken at time 0, and 24 hours to assay changes in cell migration with Image J software. Treated TNBC cells were then processed for western blot analysis to determine changes in the levels and activity of signaling pathways.
This work is the first to characterize the effects of BMI on human peritumor adipose tissue on TNBC cells, demonstrating a novel new system for studying the effect of obesity on peritumor ADS regulation of TNBC cell signaling and invasiveness. In addition, we investigate the effect of BMI on the regulation of signaling and invasiveness of TNBC cells by peritumor breast adipose tissue secreted factors. We hypothesize that high BMI ADS has a stronger cancer promoting effect on TNBC cells than low BMI ADS and this could in part underly the mechanism by which obesity promotes TNBC progression