Kerman University of Medical Sciences

Simorgh Research Repository
Not a member yet
    16687 research outputs found

    Factors affecting pre-pregnancy care among women based on the theory of planned behavior in Larestan, Iran, in 2016

    No full text
    Aim: Pre-pregnancy care is a series of interventions aimed to identify and modify behavioral and social risk factors and improve women�s health before pregnancy. The aim of this study was to investigate the factors affecting pre-pregnancy care based on the theory of planned behavior in women aged 15�49 years in Larestan city, Shiraz, in 2016. Subjects and methods: In this descriptive-analytical, cross-sectional study, all women aged 15 to 49 years, who agreed to complete a self-administered questionnaire based on the theory of planned behavior, were included. Predictors of pre-pregnancy care intention and behavior were identified using linear and logistic regression. Results: The results showed that 46.4 of women had received pre-pregnancy care. The most important predictors of intention were attitude (P < 0.001) and subjective norm (P < 0.001), and the most important predictors of the behavior were knowledge (P < 0.001) and perceived behavioral control (P = 0.010). Conclusion: To increase women�s tendency to perform pre-pregnancy care, physicians and health care providers should increase women�s knowledge by emphasizing the benefits of pre-pregnancy care for the mother, child and family, and they should try to encourage women to perform pre-pregnancy care. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature

    The assessment of apoptosis, toxicity effects and anti-leishmanial study of Chitosan/CdO core-shell nanoparticles, eco-friendly synthesis and evaluation

    No full text
    Leishmaniasis is a parasitic disease that can be transmitted to individuals by a species of the Leishmania flagellated protozoan. Due to problems such as toxicity, high cost, long duration of treatment, increased drug resistance, painful injections, and side effects, leishmaniasis is considered as an important epidemic in people with systemic deficits. Therefore, in this study, new core�shell nanostructures were introduced as anti-leishmanial drugs for the first time. The expression of IFN-γ, TNF-α, IL-4, and IL-12 genes were evaluated by real-time PCR. Investigations revealed that CdO/Chitosan core shell nanostructures decreased the proliferation of promastigotes (p &lt; 0.0001). The number of promastigotes were reduced in the presence of different concentrations of the nanostructures. The average value of IC50 for promastigotes was about 0.6 µg/mL. The concentration of the drug that prevented the growth of 50 of macrophages for core shell nanostructures was 1.256 μg/mL. The level of apoptosis in leishmania promastigotes in the presence of nanodots at the concentrations of 1, 0.5, and 0.25 µg/mL was 56, 31, and 23, respectively. Furthermore, according to the results, it can be concluded that the level of gene expression pertaining to Th1 was significantly up-regulated (p &lt; 0.001). This study showed that the core�shell nanodots of chitosan/cadmium oxide inhibit the proliferation of promastigotes and increase the apoptosis of leishmania promastigotes. © 2021 The Author

    13,094

    full texts

    16,687

    metadata records
    Updated in last 30 days.
    Simorgh Research Repository
    Access Repository Dashboard
    Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇