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A Systematic Review Comparing Dexmedetomidine and Fentanyl for Attenuation of the Sympathetic Response to Direct Laryngoscopy
Sympathetic activation, manifesting as tachycardia and hypertension, is a known occurrence following direct laryngoscopy and endotracheal intubation. Although considered transient and benign in most patients, the marked hemodynamic changes can precipitate perioperative cardiac events in patients with preexisting cardiac risk factors. Perioperative cardiac events are associated with increased morbidity and mortality, prolonged hospitalizations, and increased hospital costs. A multitude of pharmacologic agents have been employed to mitigate the tachycardia and hypertension associated with airway manipulation. Fentanyl is the adjuvant agent most commonly administered to facilitate induction of anesthesia and subsequent airway manipulation. Dexmedetomidine, another adjuvant, has demonstrated effectiveness in suppressing the hemodynamic response to intubation as well as potentially reducing perioperative ischemic events. The purpose of this systematic review was to compare the effectiveness of dexmedetomidine to fentanyl for attenuating the sympathetic response to direct laryngoscopy and endotracheal intubation. Literature and pertinent randomized control trials were searched for inclusion within this review. Four trials were included in this systematic review using the PRISMA checklist. Data was collected from each study and critically appraised using the CASP tool, and a cross analysis was then performed. This systematic review found dexmedetomidine to be superior to fentanyl in attenuating the hemodynamic response to airway manipulation. However, further research is necessary to better determine the effectiveness of these medications on patients with preexisting cardiovascular disease
It\u27s Not Busy Work
When the COVID-19 pandemic hit Kansas State University, all campuses closed, and staff were sent home. While many staff members\u27 work could easily be done outside of the library, there were a significant number of people whose work was tied to the physical building or campus. Several weeks into the pandemic, some staff were running the risk of not getting paid due to lack of work.
An archivist and the web services librarian got together to develop several digital projects that could be completed at home without any special equipment other than a computer and internet. Those four projects included documenting the histories of people and departments at K-State, creating a timeline of university activities, and two citizen archivist projects. These projects help make university history and information accessible and visible to people around the world
When will my reflection show who I am inside? : Queering Disney Fantasy
In this thesis, I argue that the treatment and seemingly progressive representation of gender and queer identity in Disney films serves merely as a form of baiting to modern audiences, a baiting that suggests Disney wants to be understood as having embraced the ideas of progressive feminism and homosexually-inclusive ideologies, only to undermine and disavow them with a bait and switch narrative maneuvering that undercuts the film\u27s ostensible message. I analyze and interpret the ways in which classic Disney animated features represent gender and sexual identity binaries through a close reading of Bambi (1942), Mulan (1998), and Frozen (2013). I bring together Lacan\u27s notion of the mirror stage, the Symbolic order, and the idea that at the heart of identity lies a fundamental misrecognition, which leaves children especially vulnerable to the hail of ideology as it informs nearly the entirety of a child\u27s headspace. Today, gender and sexual binaries are challenged at every level, and Disney seems to have embraced this progressive trend. Yet the lack of proper representation of LGBTQ characters and the negative subsequent treatment of those allowed to be seen in its films complicates this evolutionary progress that Disney claims it has achieved
Dispatches from Kindergarten Felix
https://digitalcommons.ric.edu/hbs_time_cap/1003/thumbnail.jp
Function of spiny dorsal fin erector muscles in the bluegill, Lepomis macrochirus
Local motor control directly contributes to stability, which can be compromised by injury or multiple neuromuscular disorders. In addition, lack of sensory perception as experienced by decreased limb sensation can further deteriorate one’s quality of life. The goal of this study is to use bluegill (Lepomis macrochirus) fins as model systems to study and gain insights on local motor control and sensory perception to improve stability and locomotion in humans, especially in a rehabilitative state. We hypothesize that 1) when exposed to turbulence (T), bluegill will use the spiny dorsal fin to recover stability and muscle intensity and duration will increase in the spiny dorsal fin erector muscles; 2) we expect the removal of afferent information, by injection of lidocaine, to decrease muscle intensity and duration compared to saline (control); and 3) the removal of muscle control by injection of flaxedil, to dramatically decrease muscle intensity and duration compared to saline. Upon sedation of the bluegill, the epaxial and spine erector muscles were implanted bilaterally with double insulated electrodes via hypodermic needles, followed by injection of 0.6 mL (0.1 mL per erector muscle) with one of the three treatments: flaxedil (0.04mg/mL), lidocaine (1.25mg/mL), or buffered saline. Muscle activity was recorded with an iWire-BIO8 biopotential recorder module and two high-speed cameras for the top and side views of the tank. The findings showed that turbulence within each treatment did not affect magnitude, relative intensity, burst duration, cycle duration, or duty factor of erector or epaxial muscle bursts. However, within no turbulence conditions, lidocaine treated fish had higher muscle activity in the spiny erector muscle magnitude than the flaxedil treatment. Activity bursts of spiny erector muscle were shorter under flaxedil than control under turbulent conditions. While under no turbulence relative intensity also decreased under flaxedil conditions. We found that in lidocaine treated fish, the erector muscles were unable to correctly modulate muscle activity and that in flaxedil fish, erector muscle function was compromised. Findings on impaired motor control and blocked sensory perception may be applied to enhance human prosthetic control and thus achieve stability
Considering Disability
This independent study concentrated on using collage to visually manifest intangible concepts and experiences related to disability. This objective was addressed through the techniques used in each piece’s subject matter and their physical construction. The main concept behind these collages was inspired by contemporary philosopher Elizabeth Barnes who among other researchers, has argued that disability should in no way be considered as a sub-optimal lifestyle, but maintains that in and of itself, disability can be a harm. My aim in completing this study was to investigate different methods in which I could achieve effective visual communication of abstract concepts and experiences. More specifically, my intention was to work with the given attributes of magazine paper such as line, color, and value in order to capture and convey this discussion surrounding disability
An Investigation of Form and Function in Greek Pottery
This work investigates the relationship between form and function in Greek Pottery. Vessels are recreated in different ways that experiment with tipping the scales between form and function