Engineering Conferences International
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Evolution of higly efficient t7 Rna polymerase for Mrna production using aptamer-based fluorescence-activated droplet sorting
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Enzyme Engineering in Synthetic Biology
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Enzyme engineereing of glutamate dehydrogenase for production of L- amino acids
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The Engineering of Directed Evolution
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Expanding the enzymatic toolbox with de novo protein design
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Clean dry etching of Cu and Ni alloy metal thin film by reactive proton assisted etching
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Ultra-sensitive and portable organic electrochemical transistors for noninvasive saliva glucose monitoring
Get PDFAbstract: Currently, there is no available approach for non-invasive glucose monitoring in the human saliva fluid because of its low glucose density, complex salivary composition, and poor blood correlation. Here, we report a non-invasive, ultra-sensitive, enzymatic stable, and continuous saliva glucose monitoring system based on an organic electrochemical transistors (OECTs), which can be real-time and wirelessly monitored and analyzed saliva glucoses with a portable meter and a mobile smartphone. The system presents a stable sensing performance in monitoring saliva glucose for over 12 hours with high sensitivity (1 × 10-9 M). The clinical trials results for saliva glucose showed a monoclinic relationship between the fasting glucose levels of saliva and blood with little deviation (~10%) in 102 human samples in different gender/age groups of with and w/o diabetics. A delay of glucose level in saliva to blood with a more complicated relationship was obtained in continuous saliva glucose measurement. This approach paves the way to clinically non-invasive and continuous glucose monitoring based on thin film transistors.
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Tissue classification of breast cancer by hyperspectral unmixing
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High-density speckle contrast optical tomography of cerebral blood flow of the adult brain
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