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Environmental Stimuli and Intragenerational Epigenetics
Epigenetics is the study of any change in gene expression that is not mediated by DNA sequence. The effects of environmental stimuli on epigenetic changes have been studied extensively in recent years. Multiple reviews have provided comprehensive summations of the effects of environmental stimuli on transgenerational epigenetic changes, but few reviews have focused upon environment-induced intragenerational epigenetic changes. This review will summarize current knowledge of the intragenerational epigenetic changes that are induced by two groups of well-studied environmental stimuli: nutritional deficiencies and carcinogens. This survey of intragenerational epigenetic changes will focus upon the mechanisms behind them, the disorders associated with them, and the interactions between them
Spice Nuggets
Spice Nuggets
These are the products –
Silk saris,
dyed in
purple, pink, yellow, and orange,
transported from Xinjiang to Beijing.
Wool rugs,
woven in
blue, gold, brown, and burgundy,
carried from Kashmir to Xanadu.
Spice bundles,
composed of
anise, mace, nutmeg, and cloves,
shipped from Molluca to Lisbon.
Gold nuggets,
molded into
rings, pendants, swords, and coins,
hauled from Kathmandu to Madrid –
That motivated the formation
of so many roads and routes.
These are the crafts
That created the connections
Between so many cultures and natures