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South Africa PhD programme
No full textPresentations SA PhD Project Conference: Free State 25-26 February 201
Completing your PhD while in full time employment: supervisor reflections?
No full textPresentations SA PhD Project Conference: Free State 25-26 February 201
NRF Open Access Statement: role of students, requirements and impact of NRF Funded Electronic Theses & Dissertations (ETDs) submissions
No full textPresentations SA PhD Project Conference: Free State 25-26 February 201
Completing my PhD whilst working full time
No full textPresentations SA PhD Project Conference: Free State 25-26 February 201
Infrastructure funding instrument
No full text6th Annual NRF Research Administrators Workshop, 30th September - 2nd October 2015, Summerstrand Hotel, Port Elizabeth Theme: Optimising research partnerships for a sustainable future
Gas bubble formation in fermenting and non-fermenting yeasts
No full textLiterature previously suggested that intracellular gas bubble formation cannot occur in microorganisms even under high gas supersaturation. This observation was disproved with the discovery of gas bubbles in the yeasts Saccharomyces cerevisiae (baking industry) and Saccharomyces pastorianus (Brewing industry). As a result the missing link between the excessive production of carbon dioxide (CO2) by alcoholic fermentation inside the yeast cells and the vigorous release of this CO2 into the surrounding environment was uncovered. Further investigations proved that CO2 was indeed the gas contained inside these gas bubbles yet additional analysis of this gas composition was still needed.
Here we investigate the occurrence of gas bubbles in yeasts that are fermenting and non-fermenting to identify any occurring differences and conserved status of gas bubbles formation in yeasts. Gas bubbles occurring in Crabtree-positive fermenting yeasts were observed to be more than those formed in the other yeasts (Crabtree-negative and strictly respiring yeasts). Although this was observed only on fermentable media, while on non-fermentable media less or no gas bubbles were formed. Furthermore, the Crabtree-negative fermenting and strictly respiring yeasts revealed similar results on both fermentable and non-fermentable media, with little to no gas bubble formation. Gas composition analysis was also carried out on three Crabtree-positive yeasts and it indicated the occurrence of five elements that were expected to be present in our samples. Moreover detection of sulphur compounds was observed in the same three samples with varying intensities. Nonetheless further research is still needed to confirm the point of production for these compounds, using more specific and sensitive techniques. From these findings it can be concluded that gas bubble formation is conserved in yeasts, with the amount of bubbles formed depending on the mode of CO2 production. In addition, it is possible that other gases or compounds such as sulphur compounds can be contained inside these gas bubbles.National Research Foundatio
Public science engagement and communication: surveying current trends in SARChIand CoE’s
No full textDevelopment of organosilane-containing bioorganometallic compounds evaluated as antiparasitic agents against plasmodium falciparum and trichomonas vaginalis
No full textMany successful initiatives have been employed to stem the spread of the diseases such as malaria and trichomonas's. However, in cases where infection has occurred, pharmaceutical treatments are required. A problem seen across the board is the development of resistance to known treatments. An even bigger problem has been the development of resistance to promising compounds during the clinical trial phase. This has led to the need for effective treatments which are able to overcome the resistance problem. This study investigated the synthesis, characterisation and pharmacological evaluation of new bioorganometallic organosilane-containing compounds based on thiosemicarbazone (TSC),quinoline and benzothiazole scaffolds. Selected thiosemicarbazone-containing ruthenium(II), rhodium(III) and palladium(II) metal complexes were also studied. The compounds were screened for antiplasmodial and antitrichomonal activity, along with their activity against A2780 human ovarian carcinoma and WHCO1 oesophageal cancer cell-lines.National Research Foundatio
Understanding your subject : the case of human and social sciences in African higher education
No full textPresentations SA PhD Project Conference: KwaZulu-Natal Province 17 August 2016.Introduction
African Higher Education and its Relevance for Sustainable Socio-economic Development
African Higher Education and its Contribution to Innovation and Community Engagement
The Value Proposition of Integrating African Indigenous Ways of Knowing and Knowledge Production in Higher Educatio
Fictional responses from Vonesh et al.
No full textVonesh et al. (2017) in their critique of Dick et al.
(2017) erect a straw man with their thought experiment;
they look for reasons why comparative functional
response (CFR) might fail, when CFR clearly
and repeatedly succeeds