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Community violence and mental health symptoms among adolescents in South Africa: a systematic review and meta-analysis
Get PDFThere is a global prevalence of youth exposure to community violence. This is notably pronounced in South Africa, where children and adolescents face elevated levels of violence. Existing systematic reviews have predominately focused on international contexts, leaving a gap that requires comprehensive analysis within the South African context to understand the situation in comparison to global trends. The objective of this study was to synthesise the available literature on adolescent exposure to community violence and its impact on mental health outcomes in South Africa. The study aimed to determine the prevalence of such exposure among South African adolescents, explore associated internalising and externalising mental health symptoms, and assess the extent of this relationship. A systematic search of electronic databases was conducted, encompassing studies published between 2010 and 2022. Eighteen studies focusing on adolescents aged 10 to 19 years, investigating exposure to community violence and mental health outcomes were included. Meta-analytical procedures revealed that South African adolescents face elevated levels of both witnessing and direct victimisation of community violence, accompanied by heightened mental health symptoms, particularly in depression and posttraumatic stress disorder. Although a moderate positive correlation between community violence exposure and depression was identified, statistical significance was not achieved. Subgroup analyses, to explore gender as a potential moderating factor was conducted. This study underscores the urgent need for targeted interventions and policy measures to address the impact of community violence on adolescent mental wellbeing in South Africa. These findings contribute to the existing literature by providing an understanding of the situation in the South African context compared to global estimates, offering recommendations for future research to inform more effective public health strategies.Thesis (MA) -- Faculty of Health Science, School of Behavioural & Lifestyle Sciences, 202
Bioprospectin of medicinal cannabis from Eastern Cape, South Africa
No full textCannabis sativa L. (Family Cannabaceae) has continued to attract much interest among natural product scientists in recent time because of its known medicinal values and remarkable chemical diversity. This study reports the investigation of C. sativa cultivated in the Eastern Cape Province of South Africa, with a view to obtaining its chemical fingerprint and isolating compounds from its stem bark for possible biological applications. Fresh and dried leaves, flowers, stem barks and roots of two Cannabis cultivars were obtained under permit NO. PIA-HP-EC-2022-0023. The fresh and dried plant materials were extracted for their essential oils (EOs), using hydro-distillation method on a Clevenger apparatus set at optimum extraction condition. The EOs were characterized by a gas chromatography coupled to a mass spectrometer (GC-MS). The chemical components of the EOs were elucidated based on their retention indices, as well as with reference to literature report. Other portions of the dried leaf, inflorescence and stem bark of each cultivar were extracted with methanol. The methanol extract was profiled for its cannabinoid content using liquid chromatography mass spectrometry (LCMS) based metabolomics approach, with reference to standard cannabinoids (∆9-THC, ∆9-THCA, and CBD). Lastly, the dried stem bark of Cultivar II was investigated for its compounds. The stem bark powder was subjected to sequential extraction at room temperature with n-hexane, dichloromethane, ethyl acetate and methanol. Based on the TLC analysis, the afforded n-hexane and ethyl acetate extracts were further individually fractionated on a repeated column chromatography, using silica gel and Sephadex LH20 as stationary phases. The column fractionation process led to the isolation of seven compounds, E1-E4, A20, A21, and A23. The isolated compounds were characterized by spectroscopic and spectrometric methods on nuclear magnetic resonance (NMR) spectrometer and ultra high-performance liquid chromatography hyphenated to a mass spectrometer, respectively. The results from the study showed that the EOs of the C. sativa cultivars contain majorly sesquiterpenes in their oxygenated and non-oxygenated forms. Caryophyllene (0.6421.4%), caryophyllene oxide (1.27-20.34%), -pinene (0.35-13.21%), D-limonene (0.51-10.99%), humulene (0.37-10.56%), humulene-1,2-epoxide (0.45-5.98%), pinene (0.16-5.22%), nerolidol (0.32-4.99%), -myrcene (0.31-4.23%), -selinene (0.92-2.51%), and trans--bergamotene (0.50-2.70%), were the main terpene constituents of the EOs in both cultivars. Neutral cannabinoids were also detected in both cultivars with cannabidiol found in significant amount up to 85.03% in the fresh stem oil (LSO) of Cultivar I (Lifter). LC-MS fingerprints revealed that Cultivar I had the highest accumulation of cannabinoids with CBDA having the highest amount (88.65%) in the stembark and CBD at about 23% in the leaves. The inflorescence (flower) contained 51.55% of CBDA. Cultivar II had the least number of cannabinoids but contains the highest amount of ∆9-THCA (94.8%) in the leaf sample. Cultivar II showed ∆9-THCA and ∆9-THC dominant profiles with less than 2% of ∆8-THC. ∆9-THC, ∆8- THC were the only neutral cannabinoids detected in Cultivar II while CBD, ∆9-THC, and ∆8- THC were found in significant amounts in Cultivar I. The compounds isolated from the stem bark of Cultivar II were elucidated as five triterpenoids: Sativalenic acid ethyl ester (E1), Phyllanthone (E2), Friedelin (E3), Sativalonone (A20) and Sativaol (A23); an alkaloid, Sativacherine (E4); and a fatty acid ester, Ethyl stearate (A21). Four of these compounds are newly described, while all the compounds are reported for the first time from the Eastern Cape Cultivar (Cherrywine) of C. sativa stem.Thesis (PHD) -- Faculty of Natural Sciences, 202
The rise of ‘violent non-state actors’ in South Africa: an analysis of the taxi industry in the Eastern Cape Province
No full textThis study investigated the rise of ‘violent-non state actors’ in South Africa, with specific focus on the taxi industry in the Eastern Cape Province. Contemporary South Africa has been a playground for violent non-state actors often evidenced by sporadic service delivery protests and gun violence in public spaces. Many authors attribute these to the failure of the state to provide public services such as security, water, employment, etc. Amongst these non-state actors, are taxi associations called mother-bodies. The deregulation of the taxi industry by the then apartheid government in 1987 resulted in the exponential inflow of previously oppressed black people into the taxi industry, which had now become the most accessible form of informal business for previously disadvantaged people. This resulted in the formation of many mother-bodies that subsequently became ‘law unto themselves’ due to the absence of formal state regulation amongst other things. Since then, violent conflicts amongst these mother bodies have become the order of the day. The study sought to determine the commuter’s perspectives about the taxi industry and violence in the Eastern Cape Province, to determine ways in which the taxi industry has challenged the monopoly of the state over the legitimate use of force and to explore the reasons why taxi violence has largely gone unchecked by the state. Part of the key findings of the study were that there is a general sense of fear and insecurity amongst commuters especially female commuters who use taxis. Various cases of sexual assault, intimidation and psychological traumas caused by exposure to violence amongst commuters have been reported. It has also been determined that in order to effectively challenge the monopoly of the state over the legitimate use force, some taxi operators have resorted to the use of self created laws to intimidate their competitors, use of mafia-like tactics, extortion and coercion amongst other things in order to impose monopoly over some lucrative routes, individuals and associations. In resolving some of these challenges, the study inter alia recommends for the formalization of the taxi industry by government, which will result in the subsidisation of the industry.Thesis (PhD) -- Faculty of Social Sciences and Humanities, 202
Decolonizing Journalism Education in South Africa
No full textThe British, French, and Portuguese regimes colonized most African countries. This colonization took away African languages, cultures, religions, and practices, only to replace them with colonial traditions. Decolonization debates are now rife in South Africa: decolonizing higher education, the economy, the law, and the justice system. All these debates and attempts are made to achieve equity and justice in the country. To contribute to these debates, this chapter examines how journalism education can be decolonized in South Africa from a sociolinguistic perspective. To achieve its aim, the chapter will review course descriptions of journalism curriculums at three universities in South Africa that offer journalism education and possible ways to decolonize the curriculums from the sociolinguistics perspectives. The chapter has concluded that sociolinguistics is critical in decolonizing journalism education. Journalism is a verbal medium; it uses language to communicate. Hence, it is essential for journalism curriculums in South Africa to teach students that language and identity can influence journalism practice to reflect its context and speak to its people in a language and forms that they understand
Zulu Ethnolinguistic Nationalism
No full textLanguage is more than just a communication medium; it exists within interrelated social and political processes. Therefore, language never appears by itself; it always represents a system of social and political interests, reflecting the prevailing discursive and ideological strategies. The current chapter investigates the notion of “Zulu ethnolinguistic nationalism” as a language ideology in South African television. Having watched a series of television programs in South Africa and utilizing the corpus linguistic approach, the author asserts that there is a clear dominance of isiZulu in South African television. Ultimately, this dominance created a language ideology that privileges isiZulu over other indigenous languages on South African television
Ideologies of Colonial-Apartheid Linguistic Order
No full text7de Laan uses primarily Afrikaans and English, with indigenous languages used instantly; My Desire is dubbed from Hindi to English only. The chapter aims to demonstrate how using English and Afrikaans in 7de Laan and dubbing Hindi into English in My Desire promote ideologies of Colonial-Apartheid linguistic order. The chapter argues that the use of Afrikaans in 7de Laan and English dubbing in My Desire are primarily homogenous. When indigenous languages are excluded in 7de Laan and dubbing in My Desire, it is not just about 7de Laan being an Afrikaans soap opera or My Desire promoting English over indigenous languages. This is also about creating an environment where the Colonial-Apartheid linguistic order can be established and sold to viewers. It is about rejecting the post-Apartheid notion of the Rainbow Nation
Challenges and opportunities of Facebook during bereavement
Get PDFBereavement is something that we experience in one way or another. It involves many steps from one culture to the other. Many scholars have documented the role of social media tools in bereavement processes. In this study, I look at the challenges and opportunities offered by Fa-cebook during bereavement, especially in a community that is still tradi-tional and has yet to fully comprehend the importance of social media, particularly in matters considered sacred. The study used interviews with residents from Taung to collect data. Thematic analysis was used to analyze the collected data from the interviews. The study findings indicate some challenges associated with bereavement on Facebook: emotional shock, lack of sensitivity, misinformation, and cultural dilution. There are also opportunities: fast news sharing, ongoing emotional support, and sharing of memories. The study argues that the findings should expand our understanding and knowledge of bereavement in some African cultures and use social media tools to complement and not destroy African beliefs and practices
Black Twitter and Digital Counterpublics in South Africa
Get PDFThe growth of technology has made the Internet an essential tool in so-ciety. Scholars have argued that the Internet supports a more delibera-tive democracy. However, scholars have also raised concerns about the role of the Internet in political matters. While scholars agree that the Internet has facilitated broader public discussion, in many regards, its ‘virtual public sphere’still mirrors existing social structures. Twitter has become a common social media platform for many South Africans. This has led to a virtual community of Twitter users engaged in real-time dis-courses primarily related to Black South Africans. Black Twitter in South Africa is used for social, political, and economic motivations. This study argues for the practice of Black Twitter as a digital counterpublic in South Africa. The aim is to spotlight how black people in South Africa have used Black Twitter as a digital counterpublic for the marginalized groups within South Africa. The research will investigate the potential challenges and opportunities associated with Black Twitter functioning as a digital counterpublic. Utilizing digital ethnography, the study gath-ered a dataset of tweets from Black Twitter in 2022, focusing on those addressing social, political, and economic issues. More than 700,000 tweets were identified under these specific thematic hashtags
Household food security status and its determinantsin Mthata Eastern Cape Province
Get PDFFood security remains a critical issue worldwide, and South Africa is no exception. This national challenge is especially acute in the Eastern Cape Province, known as one of the poorest regions in the country. The highest rates of poverty are observed in the Eastern Cape Province, with the population largely dependent on social grants to secure their food needs. The primary objective of the study was to examine the household food security status and its determinants in Mthatha, Eastern Cape Province of South Africa. The study was conducted in Tabase and Ncise in Mthatha. The purposive sampling technique was employed in the study and 336 data points were achieved. The study used the Household Food Insecurity Access Scale (HFIAS), developed by the USAID-funded Food and Nutrition Technical Assistance II (FANTA), and leveraged Tobit regression analysis, particularly advantageous for handling censored dependent variables, to examine the determinants of food household food security. The results revealed that gender, age, crops and social grants have no statistical significant relationship with food insecurity. Education, employment status, income, livestock and dietary diversity have a statistical significant relationship with food insecurity. Results further revealed that 40.36% of households were food insecure while 4.22% were food secure, 7.83% were mildly food insecure and 40.36% were severely food insecure. The study recommends the formation of agricultural cooperatives with government support, prioritising education incentives, and strengthening existing food support initiatives. It emphasizes promoting savings clubs and subsidising nutrient-rich foods to enhance accessibility. These multifaceted recommendations aim to address household food security in Mthatha, providing a comprehensive framework for intervention and policy considerations.Thesis (Masters) -- Faculty of Economics and Finacial Sciences, 202
An in vitro assessment of pharmacodynamic interactions between selected herbal extracts and anticancer chemotherapeutic agents
Get PDFCancer is a disease caused by uncontrolled growth and spreading of abnormal cells to distant body parts. Approximately 19.3 million and 10 million new cancer cases and cancer deaths, respectively were recorded in 2020. Despite advancements in prevention and therapeutic strategies, cancer remains a global health problem. Cancer patients are increasingly seeking complementary and alternative medicines, of which herbal medicines are the most common form of CAM used by patients. Numerous in vitro and in vivo studies of herbal medicines in cancer have shown that they have antioxidant and anticancer (antitumor and anti-proliferative) properties. While concurrent use with conventional cancer treatments may improve treatment efficacy, alleviate chemotherapy-related side effects, boost the immune system, or impede drug resistance, it can also prompt drug-herbal interactions, and this may affect the pharmacodynamics and pharmacokinetics of the chemotherapeutic drug. This study aimed to determine relevant pharmacodynamic interactions with chemotherapeutic drugs and investigate such interactions' mechanisms. The objectives of the study were to screen the cytotoxicity effects of drug compounds, herbal extracts, and drug-herb combinations, to determine the ability of treatments to induce apoptosis, and to determine the most beneficial treatment. The cytotoxic effects of cisplatin in HeLa cells, tamoxifen in MCF7 cells, 5-fluorouracil in Caco-2 cells, and grapeseed, green tea, fermented rooibos, and green rooibos in all the listed cell lines were evaluated individually and in combination using the bis-Benzamide H 33342 trihydrochloride/propidium iodide (Hoechst 33342/PI) dual staining method. CompuSyn 1.0 Software was used to quantify synergism and antagonism. The mechanism of apoptosis induction of the different synergetic combinations, drug compounds, and herbal extracts was illustrated by quantitative fluorescence image analysis, specifically cell cycle analysis, phosphatidylserine translocation, mitochondrial membrane potential analysis, caspase 3 activation, and reactive oxygen species production using the relevant contrast dyes. Grapeseed displayed cytotoxicity towards MCF7 and HeLa cells (IC50 57.98 and 83.28 μg/mL, respectively). Green tea was only cytotoxic against HeLa cells at an IC50 of 91,92 μg/mL. None of the extracts displayed cytotoxicity against Caco-2 cells (IC50 values > 200μg/mL). If the herbal extracts had inconclusive IC50 values in the three cell lines subsequent experiments were conducted using 100 μg/mL. The results showed that most of the combinations were antagonistic but, some combinations had synergistic or enhancement effects(1:3 for cisplatin with grape seed or green tea and tamoxifen with grapeseed or green tea, and 3:1 for cisplatin with green tea as well as for tamoxifen with fermented rooibos or green rooibos, and all the 1:1 combinations of 5- fluorouracil with all herbal extracts) with a combination index (CI) < 1. Grape seed and green tea were found to induce apoptosis in the three cell lines. Assays that were conducted to detect apoptosis induction showed positive staining for phosphatidylserine (PS), activated caspase 3, and reactive oxygen species (ROS), mitochondrial membrane depolarization. Analysis of the cell cycle showed two things; 1) that grape seed and green tea were apoptotic in HeLa and MCF7 cells only, and 2) the extracts of green tea and green rooibos, and the combinations of grape seed with all drug compounds arrested the cell in more than one phase of the cell cycle. The combinations of grapeseed and green tea potentially induced apoptosis in various manners but those with both rooibos extracts were unclear in all the cell lines. The results for combinations with grapeseed and green tea are promising and provide a basis for further research as combinations of chemotherapeutic drugs and herbal extracts may be effective therapeutic strategies.Thesis (MPharm) -- Faculty of Health Sciences, School of Clinical Care & Medicinal Sciences, 202