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    Analyzing agricultural financing for resettled farmers in Zimbabwe: the case of targeted Command Agricultural program in Mutare District

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    Agriculture plays a paramount role in the economy of many countries including Zimbabwe where more than 70 percent of the population depends on agricultural activities for their livelihoods. Smallholder farmers’ access to agricultural credit is vital for the development and growth of Zimbabwe’s agricultural sector, hence agricultural financing is crucial in rural development. Despite the Government’s efforts to provide affordable agricultural credit services to its majority smallholder farmers’ participation is still meager. The aim of this study is to analyze agricultural financing for resettled farmers in Zimbabwe, with special focus on the command agricultural loans in the Mutare district. A multistage sampling technique was employed in this study. Firstly purposive selection of Manicaland province was carried out because it is endowed with the five natural farming regions found in Zimbabwe. The second stage involved a random selection of 4 out of 7 districts with favorable climatic conditions for maize production. Thirdly, the study also carried out a purposive selection of Mutare district among the four districts with favorable climatic conditions, given the time and financial constraints. The last stage involved the use of stratified sampling technique, where the sample was divided into two strata. Stratum 1 with A1 farmers and stratum two consisting of A2 farmers, and a random sample was selected from each stratum. The study involved 301 A1 farmers and 49 A2 farmers, making a total sample of 350 farmers used for this study. Double hurdle was employed to examine the factors influencing A1 and A2 farmers` participation in command agriculture loans in the study area. Multinomial logistic regression model was also applied to investigate the determinants of command agriculture loan repayment, while propensity score matching technique was used to examine the impacts of command agriculture loans on maize productivity and profitability of A1 and A2 farmers. The results revealed that family size, and distance from the market GMB positively influence farmers likelihood to participate in in the command agricultural loan. While family size, farmer type and distance from the market were proven to have a positive significant influence on the extent of participation in command agriculture. Also training on the command agriculture loan and gender were proven to have a negative signification influence on the extent of farmers` participation in command agriculture loan. The maximum likelihood estimates of the multinomial logistic regression revealed that age and output levels significantly influence resettled farmers` likelihood to partly pay their loans. Also, the likelihood estimates of the multinomial logistic regression showed that distance from the market and output levels have a positive influence on resettled farmers` likelihood of fully paying the command agriculture loan. Access to extension services to extension services was proven to negatively influence farmers` likelihood to fully pay the loan. The results also revealed that participating in command agriculture significantly impacted productivity at the 1 percent level, while it was not significant in the participants' profitability. The results show that participating in command agriculture increases productivity by 0.93 tonnes hectare. The study recommends the intensification of extension service supply to ensure that farmers are receiving relevant agricultural training, mainly on climate change adaptation strategies. This will help resettled farmers to adjust and adapt to their new farming environments and, in turn, have a positive impact on their production levels. Also, to improve farmers’ profitability the GMB selling price should be in American dollars USD and not paid in part RTGS and part USD, because the RTGS part is always outstripped by inflation.Thesis (MSc) -- Faculty of Science and Agriculture, 202

    Enhancing the electrocatalytic activity of phthalocyanines through finding the ideal combination of substituents in push-pull phthalocyanine-based systems

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    Phthalocyanines (Pcs) are a class of synthetic pigments with a similar structure to porphyrins. The work presented in this thesis is centred around these electron-rich macrocycles and their use in electrocatalysis. This body of work provides a more rigorous analysis on asymmetric Pcs, focusing on finding the “ideal” combination of substituents in the synthesis of A3B-type Pcs and how these asymmetric structures compare with their symmetric counterparts (A4) in the electrocatalysis of hydrazine and nitrite. The choice in substituents in the syntheses of the Pcs was such that there is both electron-donating and electron-withdrawing groups to induce a push-pull effect. In the studies involving the electrocatalysis of hydrazine, asymmetric cobalt Pcs (CoPcs) possessing alkyl groups as the primary substituents, with variations in the acid-containing group, along with their symmetric counterparts, probes with potential for further improvement were identified. Using voltammetric and amperometric techniques, the analyte-electrode kinetics, mechanism in which the electrochemical reaction proceeds along with the limits of detection (LoD) were determined. In the general sense, the pentadecylphenoxy-derived CoPcs performed better than those containing the tert-butyl substituent as the dominant substituent with the asymmetric CoPcs producing more favourable results than their symmetric analogues. With respect to the probes designed for nitrite, a multi-dimensional approach was undertaken in that acetaminophen was chosen as the primary substituent whilst multiple changes in the asymmetric component were made. In addition to varying the carboxylic acid-containing substituent, alkyne- and amine-based substituents were also explored in which the alkyne-containing Pc was anchored onto the electrode surface through click chemistry while the amine-bearing Pc was covalently linked (and π-stacked) to nitrogen-doped graphene quantum dots (NGQDs). Another component that was altered was the central metal where CoPcs were compared to manganese Pcs (MnPcs). The most desirable peak oxidation potential for nitrite was observed in the MnPcs as it was the lowest with adsorption sometimes being a better suited method of electrode modification relative to clicking. The inclusion of NGQDs was found to be beneficial when combined with the symmetric CoPc whilst in the presence of an asymmetric Pc complex, less desirable results were observed. Overall, there were variations in the results with the symmetric CoPc sometimes being better than some of the asymmetric CoPcs demonstrating that a blanket-approach in terms of synthesizing and applying asymmetric Pcs is not always viable.Thesis (PhD) -- Faculty of Science, Chemistry, 202

    Coastal movements and estuarine use of sub-adult and adult leervis, lichia amia: results from long-term acoustic tracking

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    Information on fish movement is important not only for understanding a species’ ecological importance, but also for developing appropriate conservation and management policies that are critical for food security and biodiversity preservation. This information is particularly important for species that occupy different habitats at different life history stages, and display predictable movement patterns, such as an annual spawning migration. Leervis Lichia amia is an estuary-dependent fishery species of high ecological and recreational importance in South Africa. There has been a steady decline in catch-per-unit-effort in the marine recreational fishery for this species over the past 20 years, and the most recent stock assessment classified the adult stock as collapsed. This study investigates L. amia multi-year coastal migrations and estuarine habitat use of sub-adult and adult fish tagged with long-life acoustic transmitters Seventy-eight L. amia (two juveniles, fifty-four subadults, and twenty-one adults) were tagged throughout their South African distribution and monitored between 2011 and 2020 producing a decade long dataset. Results show that regardless of the tagging region, clear migration patterns were observed, demonstrating that both sub-adult and adult L. amia migrate annually to KZN in the austral winter and predictably return to the WC and EC waters in the summer. The likelihood of partial migration was also identified, with the coexistence of migratory and resident behaviors within a single L. amia population. In addition, Overwintering behaviour was also observed with L. amia adults that remained resident throughout the year, foregoing the annual migration, phenomenon known as skipped spawning, and homing behaviour, where L. amia, particularly those tagged in the EC and WC, were recorded returning to previously occupied tagging locations and surrounding areas. The importance of estuaries to sub-adult and adult fish was also assessed and identified the importance of estuaries not only to subadults but also to adults. Estuary visits were strongly influenced by the environment which the fish was tagged in, temporal and seasonal changes, and life-history stages. The predictability of their migrations (almost to the day), the varied migratory behaviour (overwintering), returning to sites of familiarity post-migration, and long-term dependency on estuaries even as sub-adults and adults, provide motivation for increased protection of this species, including extending the network of estuarine protected areas in the country, and a closed fishing season, particularly during the annual winter migration.Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 202

    Identification of novel Arf1 GTPase inhibitors for cancer target validation

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    The key regulators of both anterograde and retrograde vesicular traffic, adenosine diphosphate-ribosylation factors (Arfs), also coordinate various signalling pathways and regulate cellular processes required for cell survival and function. In addition to its role in mediating secretory trafficking in the Golgi apparatus, the involvement of Arf1 in signalling pathways that contribute to the formation and progression of cancer has become apparent, and the overexpression and deregulation of Arf1 activity has been associated with cancer cell invasion, proliferation and metastasis. As with other small GTPases, Arf1 must cycle back and forth between an inactive (GDP-bound) and active (GTP-bound) conformation to carry out its function. However, the cycle of Arf1 inactivation and activation is controlled by Arf GTPase activating proteins (Arf-GAPs) that stimulate Arf1 to hydrolyse the bound GTP to GDP and Arf guanine nucleotide exchange factors (Arf-GEFs) that facilitate GDP for GTP exchange on Arf1, respectively. The identification of Arf1 inhibitors that indirectly disrupt Arf1 function by blocking its interaction with Arf-GAPs or Arf-GEFs has generated interest in their use as possible anti-cancer agents. The suppression of Arf1 activation (by targeting Arf-GEFs) has been investigated as a potential cancer therapeutic target and resulted in inhibitor compounds that have micromolar-range activity against cancer cells and targets and promising results in mouse models, but experience problems with bioavailability when used in vivo. This motivates the search for novel Arf1 inhibitors for validation purposes to question whether Arf1 is a viable target for cancer therapy. The purpose of the study was to employ a recently developed colourimetric screening assay to identify inhibitors of Arf1 activation (Arf-GEF inhibitors) and deactivation (Arf-GAP inhibitors), with a focus on evaluating the potential of Arf1 deactivation as an entirely novel anti-cancer target. The proteins required for the assay (Arf1, Arf-GEF and -GAP domains and a reporter protein, GST-GGA3) were expressed in E. coli. and purified using affinity chromatography. The assay could detect the activation of Arf1 by the catalytic Sec7 domain of the three Arf-GEFs chosen for this study, but reproducibility was compromised by the occasional spontaneous activation of Arf1 in the absence of the Arf-GEFs. By contrast, the assay could reproducibly detect Arf1 deactivation by an Arf-GAP domain (Arf-GAP1GAP) and was subsequently used to screen a library of α-helix mimetics. Thirteen hit compounds with IC50 values ranging from 0.53 to 20.95 μM were found to inhibit Arf-GAP1GAP-mediated stimulation of GTP hydrolysis by Arf1-GTP in this assay format, however, they did not effectively suppress the proliferation of three tested cell lines (HeLa, MCF-7 and MCF-12A). Interestingly, the results obtained from fluorescence microscopy studies suggested that the compounds disrupt Golgi structure and Arf1 localisation, presumably by keeping Arf1 in its active conformation by blocking Arf-GAP1 function. This suggests that the compounds affect Arf1 function in cells, and may be used to explore the feasibility of targeting Arf1 deactivation for anti-cancer purposes in a wider range of cell lines and experiments. It has been reported that Arf-GAP1 inhibition is associated with the suppression of cell migration, and the potential of the compounds as metastasis inhibitors may also be explored.Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 202

    The use of a Subjective wellbeing scale as predictor of adherence to neuroleptic treatment to determine poor prognostic factor in African population with Schizophrenia

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    Objectives: To investigate and identify demographic and clinical predic-tors of subjective well-being in a sample of Xhosa people with schizo-phrenia on neuroleptic treatment. Methods: As a part of a large genetic study, 244 study participants with a confirmed diagnosis of schizophre-nia completed the translated SWN-K 20 scale. Internal consistency analysis was performed, and convergent analysis and exploratory analysis were conducted using Principal Component Analysis (PCA). Linear regression methods were used to determine predictors of SWBN in the sample population

    The nexus between oil prices, exchange rate and foreeign direct investment in South Africa

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    The 2000 to 2020 relationship between oil prices, exchange rates, and foreign direct investment (FDI) in South Africa presents a fascinating case in the global economics. Noteworthy is that this period is marked by some important geopolitical events, technological advancements, and economic shifts that provide a rich ground for analyzing how these three critical factors interact in an emerging country. South Africa, with its unique economic and political landscape, offers an exemplary context for exploring the dynamics of these variables and their collective impact on the nation's economic health and growth. This study conducted an empirical analysis to investigate the association of oil prices, exchange rates, and foreign direct investment (FDI) in South Africa from 2000 to 2020. The research applied the autoregressive distributed lag bounds technique (ARDL) after initial unit root tests indicated different orders of integration (1(0) and 1(1)) for the variables. The results align with the risk aversion theory, revealing a significant and negative relationship between exchange rates and foreign direct investment in the long-term. Conversely, the interaction term EXCH_OIL, interest rates, and inflation demonstrated a significant and positive relationship with foreign direct investment in both the short-run and the long-run. The Granger causality test identified a unidirectional causality from foreign direct investment to exchange rates. This study recommends implementing policies aimed at stabilizing oil prices and exchange rates to entice foreign investment into South Africa.Thesis (Masters) -- Faculty of Economic and Financial Sciences, 202

    Health capital and labour productivity in selected Southern African Development Community (SADC) Countries

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    Health plays a critical role in economic development, as it directly affects productivity and ultimately leads to higher per capita income. Within the Southern African Development Community (SADC) countries, health capital has immense significance for labour productivity, serving as a catalyst for growth. This study investigated the relationship between health capital and labour productivity in selected SADC countries from 2000 to 2020, with the chosen period primarily based on data availability and coverage for the selected countries during this timeframe. To accomplish this, the study employed the panel autoregressive distributed lag (ARDL) models and techniques, which leverage the advantages of panel data and ARDL models, enabling the analysis of both short-run and long-run relationships, providing a comprehensive understanding of the dynamics between variables over time. The data for the study period was obtained from a single reliable source, The Global Economy, ensuring credibility. The primary finding from the pooled mean group (PMG) estimator indicates a positive and significant relationship between health capital and labour productivity in the short run, suggesting that investments in healthcare can boost productivity. However, contrary to the expected theory and prior assumptions, the long-run findings reveal a negative and significant relationship. This discrepancy highlights the complexity of the health-productivity relationship and necessitates further investigation to comprehend the underlying mechanisms and design effective policy interventions. Policymakers must carefully consider these mixed findings and tailor their strategies accordingly to promote both health and productivity in the long term. It is crucial to strike a balance between immediate gains and sustainable long-term outcomes.Thesis (Masters) -- Faculty of Economics and Financial Sciences, 202

    Gender and shifting urban property relations: the impacts of tenure upgrading on women’s access to land and housing in Mdantsane, South Africa

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    A detailed empirical focus on the social impacts of progressive land policy shifts on women in Africa remains limited, particularly when it comes to urban property rights. This study examined contemporary dynamics of gender and access to urban property in the context of South Africa’s post-apartheid radical policy changes that attempt to address primarily the historical exclusion of blacks from urban property rights and housing. The thesis adopted a gendered approach to the concept of ‘access’ as an overriding concept to analyse the impacts of land tenure upgrading on women’s access to urban land and housing in Mdantsane, South Africa’s second-largest township. This study also adopts a liberal feminist perspective, particularly egalitarian liberal feminism (emanating from the works of John Stuart Mill) to explore how the post-apartheid progressive institutional and legal reforms have influenced the autonomy and power of women to access urban property rights. Through this perspective, the study also draws on several key theoretical concepts to put together a conceptual schema – a framework – that provides enhanced understanding of gendered dimensions of access to urban landed property (in this case housing). In many developing countries, there has been a shift from indigenous land tenure systems to private land ownership. These shifts were caused by several factors, including population pressure, rising land income, urbanisation, and land grabbing. International organisations such as the World Bank, the United States Agency for International Development and Department for International Development have expanded their land tenure reform programmes in developing countries from the 1970s until the late 1990s. These have suggested individualised land rights (land titling) as a precondition for investment, economic progress, poverty alleviation, and a framework for secure, transparent, and enforceable property rights. Gender equity became a growing concern among donor institutions that promote and fund titling and registration programmes. Land titling was viewed as a solution to bring an end to gender inequalities in land ownership. In South Africa, the Upgrading of Land Tenure Rights Act 112 of 1991 (ULTRA) was enacted for upgrading and converting ownership of certain rights granted in respect of land. The study used a case study of women in sections of Mdantsane. Qualitative methods, mainly in-depth interviews and life histories enabled the researcher to obtain detailed personal accounts of the historical and contemporary struggles of black women in accessing land and property in South Africa’s urban peripheries. The findings demonstrate that tenure upgrading produced differential outcomes among women in Mdantsane, and some diverse meanings that women attach to their land and houses in the context of tenure upgrading in post-apartheid South Africa. While tenure upgrading has guaranteed non-eviction for most house occupants (including women), it resulted in eviction for others. Male occupants, who secretly and fraudulently acquired the title deeds for family houses, displaced some of their women relatives. The study also established that these displacements were mostly done by those men who were regarded as heirs to property in many of the urban households. As such, they took most decisions about the formal registration of family homes, thus weakening the rights and power of women over urban property. Among the dominant meanings attached to land after tenure upgrading, women in Mdantsane generally viewed the ownership of urban property – no matter how small – as a form of empowerment, socially and economically. This study also found that after tenure upgrading, other women lost access to the accommodation they rented for more than a decade, even though they qualified to become the owners. In some instances, the politicians fraudulently sold the houses, and the occupants were thus displaced. Poor housing administration by the municipal officials was one of the reasons most occupants lost access to housing. In general, the results indicate that post-apartheid, urban land laws and policies afforded women better access to land and housing. Furthermore, in several instances, titling afforded women equal ownership rights as men compared to other tenure systems. Nonetheless, the history of exclusion still negatively affects women’s access to land and housing. Even in cases where they are not excluded, women still face social, political, and cultural constraints in acquiring urban land. Such a finding indicates that, gender-sensitive land laws and policies do not automatically lead to positive outcomes for women in South Africa’s urban peripheries. Therefore, the struggle for equal property rights does not begin and end with gender-progressive laws. Urban land policy should also grapple with past and contemporary obstacles in the implementation of legislation.Thesis (PhD) -- Faculty of Social Sciences and Humanities, 202

    Psychobiographical study of Daisy De Melker

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    Daisy Louisa C. de Melker, born on 1 June 1886, was a qualified nurse who is famously known to have poisoned two husbands with strychnine in order to receive life insurance money while living in Turffontein, Johannesburg. Later on, she poisoned her only son with arsenic for reasons which are still unclear, and he passed away soon after. She is notoriously known in history to be the second woman to have been hanged in South Africa due to receiving the death penalty. The primary aim of the study is to explore the life of de Melker to gain an understanding of her personality development, with the aim of acquiring insight into the motivation behind her behaviour. The secondary aim includes exploring apparent Cluster B personality traits. The study is exploratory-descriptive in nature and the subject was chosen through purposive sampling. The study uses a qualitative, psycho-biographical, single-case research design to study De Melker, in order to explore and describe the personality development of her from the theoretical perspectives of Kernberg’s Object Relations Theory. This specific theory was chosen as it allowed the researcher to explore Daisy de Melker’s early childhood and upbringing that impacted the formation of ‘internal representations’ of herself and other people. The theory suggests that when there is a lack of integration of object relations, which is made up of internal and external representations, it may result in the development of a personality disorder, as it places a focus on relationships being more crucial to personality development than individual drives and abilities. Data was collected by triangulating multiple sources of information. Miles and Huberman’s (1994) strategy were used to analyse the data according to three steps, which include data reduction, data display, and conclusion drawing and verification. The significance of doing a psychobiography study lies in merging of personality psychology and historical evidence which represents a growing field in the realm of biography and provides insight into personality development through a theoretical framework.Thesis (Ma) -- Faculty of Health Science. 202

    Impact of relaxing flood policy interventions on fish production: lessons from earthen pond‑based farmers in Southwest Nigeria

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    These days, aquatic (fish) welfare is a major issue and a significant component that affects fish output. Although numerous factors can be involved, climate-induced floods are one of the most critical limiting factors in the aquaculture and fisheries industry’s development. Understanding the extent of losses and damages caused by floods at the farm level will thereby exacerbate pre-emptive policy responses. Thus, the impact of floods on fish production by focusing on catfish earthen pond-based farmers in Southwest Nigeria is presented. A survey is conducted for 150 fish farms in the region. A marginal treatment effects (MTE) approach is employed to determine the heterogeneity across the households and the policy-relevant treatment effects (PRTE). The results show significant heterogeneity in the effects of floods on fish production, considering both observed and unobserved characteristics of the farmers. It is shown that flood significantly increases output loss. Furthermore, farmers with high propensity scores to flood tend to have a high likelihood of incurring output loss. The estimates of PRTE reveal that relaxing policy strategies, such as access to climate information and climate-related training and workshops, would significantly exacerbate output loss due to flood incidences. Thus, intensifying awareness and sensitization on climate change policies will address the flood menace and still increase food production

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