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LU-167.023a, View of the Rotunda
No full texthttps://digitalcommons.longwood.edu/postcard/1026/thumbnail.jp
LU-167.027a, View of the Rotunda with students sitting on bench
No full texthttps://digitalcommons.longwood.edu/postcard/1030/thumbnail.jp
The Effect of Social Media on Artists\u27 View of Their Own Art and Desire to Create
No full textThis exploratory study examined the effect posting art on social media has on artists’ views of their own art and desire to create. The role of social media in the production, sharing, and purchasing of art has increased significantly in the past years. Thus, the importance of advertising one’s art through social media has also increased. Using a 35-question survey completed by 43 people, this study investigated how the emergence of online communities, and the pressure to gain a following and please their online audiences, has influenced artists’ views of their own work. The results of this study provides some indication regarding whether social media is helpful or harmful to artists and their careers
Modeling Chilean Long-Term Swap Yields Based on the Short-Term Interest Rate: A Garch Approach
No full textThis paper models the dynamics of Chilean interest rate swap yields. It examines whether the change in the short-term interest rate exerts a decisive influence on the change in long-term swap yields after controlling key macroeconomic and financial variables, such as inflation, the growth in industrial production, the percentage change in the equity price index and the percentage change in the exchange rate of the Chilean peso (CLP). It applies the generalized autoregressive conditional heteroskedasticity (GARCH) approach to econometrically model the dynamics of the long-term swap yield to mitigate the variation in volatility exhibited in the financial markets. The results of the estimated GARCH models show that the change in the short-term interest rate has an economically and statistically significant effect on the change in the swap yield after controlling for key macroeconomic and financial factors. These findings imply that the monetary policy of the country’s central bank, the Banco Central de Chile (BCCH), has an important influence on swap yields in Chile through its effect on the short-term interest rate
LU-167.046a, Colonnade and Student Building (French)
No full texthttps://digitalcommons.longwood.edu/postcard/1054/thumbnail.jp
LU-167.045a, Student Building (French) and Colonnade
No full texthttps://digitalcommons.longwood.edu/postcard/1052/thumbnail.jp
LU-167.032a, Inside of the Rotunda with Joannie on the Stony in center
No full texthttps://digitalcommons.longwood.edu/postcard/1036/thumbnail.jp
LU-167.013b, View of the Rotunda looking towards the east wing
No full texthttps://digitalcommons.longwood.edu/postcard/1017/thumbnail.jp
Effects of supplemented methionine on the efficacy of platinum drugs in the yeast model organism
No full textPlatinum (Pt) drugs are used in half of all anticancer treatments. A common way to study Pt drugs is by using S. cerevisiae (brewer’s yeast) as a model cellular organism. One of the most commonly used strains of yeast is BY4741, which is auxotrophic for several small-molecule nutrients, including some amino acids and the base uracil. Therefore, these must be supplemented in the cell culture medium. One of the amino acids is methionine, which is known to be able to bind and even chelate heavy metals. Methionine-supplemented media continues to be used to study Pt drugs in yeast, especially BY4741, yet the potential for methionine to interfere with the activity of Pt drugs appears to be a possibility in some studies. We have investigated the toxicity of the Pt drug cisplatin in such systems and shown that methionine supplementation of the culture media affects the measured toxicity (IC50) of cisplatin and may potentially affect the uptake or localization of the drug. We have also shown that methionine inhibits the binding of Pt to model DNA in vitro. A more complete understanding of the Pt–yeast model system will clarify its use with this important class of anticancer drug