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Are nanohedgehogs thirsty? Toward new superhydrophobic and anti-icing carbon nanohorn-polymer hybrid surfaces
Full text link85% of the world’s polymers production is made up of thermoplastics, and among them, one can find: polyethylene (PE), polypropylene (PP) and polyethylene terephthalate (PET). In this study, these three polymers were applied for the first time as supports for superhydrophobic and anti-icing surfaces created using single walled carbon nanohorns (SWCNH). A facile method of thermal “feathering” was used and the obtained materials were deeply characterized using thermal (thermogravimetry, differential scanning calorimetry) and microscopic (scanning electron microscopy, atomic force microscopy, confocal microscopy) methods as well as tribological and nanoindentation tests. We show that, depending on the polymer, the process of thermal “bulk” or “surface feathering” occurs. The results supported by Hansen Solubility Parameters calculation combined with Molecular Dynamics Simulations allow to explain the stability of surfaces as well as the wetting behavior revealing that all new materials are superhydrophobic. Moreover, some of them exhibit ice-phobic properties, while droplet freezing process is well described by the dynamic growth angle model. Finally, by discussing the mechanical stability, superhydrophobic and anti-icing properties two optimal surfaces (PP + SWCNH 5 min, PE + SWCNH 10 min) are chosen. Both of them possess intermediate values of Young’s modulus and show intermediate values of static contact angle hysteresis. Since the PE-based solids show enhanced tribological performance, tests, PE + SWCNH 10 min sample emerges as the most perspective in practical hydrophobic and anti-icing applications
Comparing the effectiveness, safety and tolerability of interventions for depressive symptoms in people with multiple sclerosis: A systematic review and network meta-analysis protocol
Full text linkBackground Comorbid depression is prevalent in people with multiple sclerosis (MS). Depression is commonly untreated or undertreated, thus, there is a need for effective and safe interventions and current guidelines recommend psychological and pharmaceutical interventions for people with MS. However, research suggests that other interventions, such as exercise, could also be effective. The comparative efficacy and safety of intervention modalities have not been quantified.
We plan to conduct a systematic review and network meta-analysis to compare efficacy and safety of psychological, pharmaceutical, physical and magnetic stimulation interventions for depression in people with MS.
Methods and analysis We will search EMBASE, Medline, Cochrane CENTRAL, APA PsycINFO, Web of Science, CINAHL and PEDro from inception to 31 December 2021. Search terms will stem from three concepts: MS, depression and randomised controlled trials. Included studies will be randomised controlled trials, where participants are people with MS randomised to receive one of the aforementioned intervention types, and depression or depressive symptoms is the primary outcome, only outcome or secondary outcome with an a priori power calculation. Screening, data extraction and risk of bias assessment (using the Risk of Bias 2 tool) will be conducted independently by two reviewers. If possible, we will synthesise the evidence by fitting a frequentist network meta-analysis model with multivariate random effects, or a pairwise random-effects meta-analysis model. For each model, efficacy will be measured using a standardised mean difference, and safety using an OR. We plan to provide summary measures including forest plots, a geometry of the network, surface under the cumulative ranking curve, and a league table, and perform subgroup analyses. Otherwise, a narrative review will be provided.
Ethics and dissemination Ethics is not required for a systematic review and network meta-analysis. Results will be published in a peer reviewed journal
Deep sequencing analysis of individual HIV-1 proviruses reveals frequent asymmetric long terminal repeats
Full text linkEffective strategies to eliminate human immunodeficiency virus type 1 (HIV-1) reservoirs are likely to require more thorough characterizations of proviruses that persist on antiretroviral therapy (ART). The rarity of infected CD4+ T-cells and related technical challenges have limited the characterization of integrated proviruses. Current approaches using next-generation sequencing can be inefficient and limited sequencing depth can make it difficult to link proviral sequences to their respective integration sites. Here, we report on an efficient method by which HIV-1 proviruses and their sites of integration are amplified and sequenced. Across five HIV-1-positive individuals on clinically effective ART, a median of 41.2% (n = 88 of 209) of amplifications yielded near-full-length proviruses and their 5′-host-virus junctions containing a median of 430 bp (range, 18 to 1,363 bp) of flanking host sequence. Unexpectedly, 29.5% (n = 26 of 88) of the sequenced proviruses had structural asymmetries between the 5′ and 3′ long terminal repeats (LTRs), commonly in the form of major 3′ deletions. Sequence-intact proviruses were detected in 3 of 5 donors, and infected CD4+ T-cell clones were detected in 4 of 5 donors. The accuracy of the method was validated by amplifying and sequencing full-length proviruses and flanking host sequences directly from peripheral blood mononuclear cell DNA. The individual proviral sequencing assay (IPSA) described here can provide an accurate, in-depth, and longitudinal characterization of HIV-1 proviruses that persist on ART, which is important for targeting proviruses for elimination and assessing the impact of interventions designed to eradicate HIV-1
Financial risk protection in health care in Bangladesh in the era of Universal Health Coverage
Full text linkBackground
Ensuring financial risk protection in health care and achieving universal health coverage (UHC) by 2030 is one of the crucial Sustainable Development Goals (SDGs) targets for many low- and middle-income countries (LMICs), including Bangladesh. We examined the critical trajectory of financial risk protection against out-of-pocket (OOP) health expenditure in Bangladesh.
Methods
Using Bangladesh Household Income and Expenditure Survey data from 2005, 2010, and 2016, we examined the levels and distributions of catastrophic health expenditure (CHE) and impoverishment incidences. We used the normative food, housing, and utilities method, refining it by categorizing households with zero OOP expenses by reasons.
Results
OOP expenditure doubled between 2005 and 2016 (USD 115.6 in 2005, USD 162.1 in 2010, USD 242.9 in 2016), accompanied by rising CHE (11.5% in 2005, 11.9% in 2010, 16.6% in 2016) and impoverishment incidence (1.5% in 2005, 1.6% in 2010, 2.3% in 2016). While further impoverishment of the poor households due to OOP expenditure (3.6% in 2005, 4.1% in 2010, 3.9% in 2016) was a more severe problem than impoverishment of the non-poor, around 5.5% of non-poor households were always at risk of impoverishment. The poorest households were the least financially protected throughout the study period (lowest vs. highest quintile CHE: 29.5% vs. 7.6%, 33.2% vs. 7.2%, and 37.6% vs. 13.0% in 2005, 2010, and 2016, respectively). The disparity in CHE among households with and without chronic illness was also remarkable in 2016 (25.0% vs. 9.1%).
Conclusion
Financial risk protection in Bangladesh exhibits a deteriorated trajectory from 2005 to 2016, posing a significant challenge to achieving UHC and, thus, the SDGs by 2030. The poorest and chronically ill households disproportionately lacked financial protection. Reversing the worsening trends of CHE and impoverishment and addressing the inequities in their distributions calls for implementing UHC and thus providing financial protection against illness
Cross country determinants of investors' sentiments prediction in emerging markets using ANN
Full text linkThe paper models investor sentiments (IS) to attract investments for Health Sector and Growth in emerging markets, viz., India, Mainland China, and the UAE, by asking questions such as: What specific healthcare sector opportunities are available in the three markets? Are the USA-IS key IS predictors in the three economies? How important are macroeconomic and sociocultural factors in predicting IS in these markets? How important are economic crises and pandemic events in predicting IS in these markets? Is there contemporaneous relation in predicting IS across the three countries in terms of USA-IS, and, if yes, is the magnitude of the impact of USA-IS uniform across the three countries' IS? The artificial neural network (ANN) model is applied to weekly time-series data from January 2003 to December 2020 to capture behavioral elements in the investors' decision-making in these emerging economies. The empirical findings confirmed the superiority of the ANN framework over the traditional logistic model in capturing the cognitive behavior of investors. Health predictor—current health expenditure as a percentage of GDP, USA IS predictor—spread, and Macro-factor GDP—annual growth % are the common predictors across the 3 economies that positively impacted the emerging markets' IS behavior. USA (S&P 500) return is the only common predictor across the three economies that negatively impacted the emerging markets' IS behavior. However, the magnitude of both positive and negative impacts varies across the countries, signifying unique, diverse socioeconomic, cultural, and market features in each of the 3 economies. The results have four key implications: Firstly, US market sentiments are an essential factor influencing stock markets in these countries. Secondly, there is a need for developing a robust sentiment proxy on similar lines to the USA in the three countries. Thirdly, investment opportunities in the healthcare sector in these economies have been identified for potential investments by the investors. Fourthly, this study is the first study to investigate investors' sentiments in these three fast-emerging economies to attract investments in the Health Sector and Growth in the backdrop of UN's 2030 SDG 3 and SDG 8 targets to be achieved by these economies
Swiping right for “Mr Right”: An investigation into the relationship between tinder use and relationship attitudes and behaviors in Australian female emerging adults
No full textTinder is a popular mobile dating application among emerging adults (18 to 29-years-old) seeking new romantic and sexual partners. Tinder’s design features are proposed to encourage hookups (casual sexual relationships) while undermining romantic relationship commitment (David & Cambre, 2016). Research into female dating application users is particularly underinvestigated despite research suggesting that female Tinder users report their application use to have a greater impact upon their dating behaviors compared with male users (Newett et al., 2018). This quantitative study explores relationships between Tinder use and attitudes and behaviors surrounding hookups and committed romantic relationships in female Tinder users. It was hypothesized that Tinder users (n = 146) would engage in more hookups and place less importance on committed relationships than nonusers (n = 103). Data were collected using online surveys. As expected, Tinder users reported less-strict sexual standards scripts, lower soul-mate beliefs, greater sexual permissiveness, have greater numbers of relationships, and hookup more than nonusers. Contrary to expectations, no differences were observed between Tinder users and nonusers on sexual communion. Obtained findings suggest that Tinder may facilitate greater sexual liberality or alternatively that those already high in liberality are drawn to nontraditional forms of dating. Further research should qualitatively investigate the extent to which female dating application users are active agents in pursuing casual sex. Obtained findings have implications for emerging adults to enable informed decision-making about their Tinder use and to ensure their motivations for use are aligned with potential attitudinal and behavioral outcomes. (PsycInfo Database Record (c) 2022 APA, all rights reserved
Influence of institutional arrangements on invasive plant species management from multilevel perspectives: A case study in Vietnam’s National Parks
No full textInvasive plant species (IPS) management in national parks is a complex problem often characterised by the involvement of various organisations with different responsibilities, legal mandates, and jurisdictions. These institutional arrangements shape the structure, function, and decision-making behaviours of organisations and influence management effectiveness. Drawing on institutional theory, this study analysed institutional arrangements and how these influenced IPS management in national parks of Vietnam. Data were collected between May and July 2017 using in-depth interviews with 39 key informants with responsibilities for IPS management at different institutional levels (national, provincial, local national parks). Results demonstrated that IPS management in Vietnam’s national parks was characterised by centralised management with overlaps and gaps in vertical institutional relationships that limited the effectiveness of horizontal relationships. These characteristics resulted in a lack of clear guiding regulations and limited resources that restricted decision making and hindered implementation at the local national park level. The study highlights the need for a common set of principles across agencies, governed by an overarching body to promote constructive relationships across the vertical and horizontal institutional dimensions of IPS management
Antecedents and outcomes of open innovation
Full text linkThis doctoral research examines the drivers and outcomes of open innovation (OI). Drawing on the resource-capability based view and contingency theory, the research quantitatively analyses meta-data and firm-level data from Vietnam and reaches four main findings. First, firms with capability constraints in developing new products and business models tend to adopt OI, whereas firms with capability constraints in organising innovation team tend to stick to closed innovation. Second, the OI-performance relationship is conditional on the type of OI, the level of organisation at which OI is undertaken, the industry with which the firm is affiliated, and the level of development of the country in which the firm is based. Third, national culture dimensions moderate the OI-performance relationship in different fashions, including linear (power distance), U-shaped (individualism, long-term orientation, and indulgence), and inverted U-shaped (uncertainty avoidance). Fourth, capability training in R&D and capability training in business models mediate the OI-performance relationship, respectively. The research contributes to the innovation literature, and enhances our understanding of the antecedents of OI, the contexts in which OI enhances innovation performance, and the mechanisms by which OI leads to innovation outcomes. The research has practical implications for managers.
Keywords: open innovation, Vietnam, antecedent, outcome, resource-based view, contingency theory, capacity innovation building, meta-analysis
Cereal and oil seed crops response to organic nitrogen when grown in rotation with annual aerial-seeded pasture legumes
No full textNitrogen fixation from pasture legumes is a fundamental process that contributes to the profitability and sustainability of dryland agricultural systems. The aim of this research was to determine whether well-managed pastures, based on aerial-seeding pasture legumes, could partially or wholly meet the nitrogen (N) requirements of subsequent grain crops in an annual rotation. Fifteen experiments were conducted in Western Australia with wheat, barley or canola crops grown in a rotation that included the pasture legume species French serradella (Ornithopus sativus), biserrula (Biserrula pelecinus), bladder clover (Trifolium spumosum), annual medics (Medicago spp.) and the non-aerial seeded subterranean clover (Trifolium subterraneum). After the pasture phase, five rates of inorganic N fertilizer (Urea, applied at 0, 23, 46, 69 and 92 kg/ha) were applied to subsequent cereal and oil seed crops. The yields of wheat grown after serradella, biserrula and bladder clover, without the use of applied N fertilizer, were consistent with the target yields for growing conditions of the trials (2.3 to 5.4 t/ha). Crop yields after phases of these pasture legume species were similar or higher than those following subterranean clover or annual medics. The results of this study suggest a single season of a legume-dominant pasture may provide sufficient organic N in the soil to grow at least one crop, without the need for inorganic N fertilizer application. This has implications for reducing inorganic N requirements and the carbon footprint of cropping in dryland agricultural systems
Risk factors for momentary loss of control and subsequent abandonment of self-devised dietary restraint plans in adults with weight-loss goals: a behaviour sequence analysis approach
No full textObjective
The current study aims to improve understanding of events leading to lapses of dietary restraint, and to identify pathways to perseverance or abandonment of weight loss efforts in response to lapses. In addition, Behaviour Sequence Analysis (BSA) was also evaluated as an analytical tool in dietary behaviour.
Design
A sample of 176 adults who were engaging in self-imposed dietary restraint for weight loss were recruited to participate.
Main outcome measures
Participants were instructed to provide a detailed written timeline of an episode where they lapsed in their dietary restraint plan. They were instructed to report their preceding behaviours and internal states, and social and environmental contexts, leading up to and after their lapse in dietary restraint.
Results
Lapses in dietary restraint were precipitated by negative internal states in the presence of cues for highly palatable foods. In addition, abandonment of weight loss efforts after lapsing was preceded by dichotomous thinking, whereas perseverance was preceded by a more neutral, flexible interpretation of the lapse in self-control.
Conclusion
BSA has identified that neutral evaluation of inevitable lapses in dietary restraint are predictive of continuation with weight loss efforts, highlighting the importance of individual tolerance of lapses in self-regulation